Zobrazeno 1 - 10
of 1 096
pro vyhledávání: '"Nicholson, Jk"'
Autor:
Posma, JM, Perez, IG, Karaman, I, Gao, H, Chan, Q, Daviglus, M, Van Horn, L, Holmes, E, Nicholson, JK, Elliott, P
Publikováno v:
29th Scientific Meeting of the International Society of Hypertension (Hypertension Kyoto 2022)
E240
E240
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1032::b7141fb5647aa892b8bab09ceb6c3178
http://hdl.handle.net/10044/1/104596
http://hdl.handle.net/10044/1/104596
Autor:
Izzi-Engbeaya, C, Comninos, AN, Clarke, SA, Jomard, A, Yang, L, Jones, S, Abbara, A, Narayanaswamy, S, Eng, PC, Papadopoulou, D, Prague, JK, Bech, P, Godsland, IF, Bassett, P, Sands, C, Camuzeaux, S, Gomez-Romero, M, Pearce, JTM, Lewis, MR, Holmes, E, Nicholson, JK, Tan, T, Ratnasabapathy, R, Hu, M, Carrat, G, Piemonti, L, Bugliani, M, Marchetti, P, Johnson, PR, Hughes, SJ, Shapiro, AM, Rutter, GA, Dhillo, WS
Publikováno v:
Diabetes, Obesity & Metabolism
Aims To investigate the effect of kisspeptin on glucose‐stimulated insulin secretion and appetite in humans. Materials and methods In 15 healthy men (age: 25.2 ± 1.1 years; BMI: 22.3 ± 0.5 kg m−2), we compared the effects of 1 nmol kg−1 h−1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::413b3f52c882e3ca6c1906a624df50cf
http://europepmc.org/articles/PMC6282711
http://europepmc.org/articles/PMC6282711
Publikováno v:
Alzheimer's Research UK Research Conference 2018
Exploring Human Host-Microbiome Interactions in Health and Disease
Exploring Human Host-Microbiome Interactions in Health and Disease
Production of short-chain fatty acids (SCFAs) from dietary substrates by the gut microbiota is associated with health, with these metabolites influencing the host via the ‘gut–brain axis’. Micromolar quantities of microbially derived SCFAs are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::f329967d9503004db55d2077fef3acc6
http://hdl.handle.net/10044/1/62966
http://hdl.handle.net/10044/1/62966
Autor:
Rodriguez Martinez, A, Posma, JM, Ayala, R, Neves, AL, Anwar, M, Petretto, E, Emanueli, C, Gauguier, D, Nicholson, JK, Dumas, M
Publikováno v:
Rodriguez-Martinez, A, Posma, J M, Ayala, R, Neves, A L, Anwar, M, Petretto, E, Emanueli, C, Gauguier, D, Nicholson, J K & Dumas, M E 2018, ' MWASTools : An R/bioconductor package for metabolome-wide association studies ', Bioinformatics, vol. 34, no. 5, pp. 890-892 . https://doi.org/10.1093/bioinformatics/btx477
Summary: MWASTools is an R package designed to provide an integrated pipeline to analyze metabonomic data in large-scale epidemiological studies. Key functionalities of our package include: quality control analysis; metabolome-wide association analys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::08116e4537f951ead77cb1fd1b19730e
https://research-information.bris.ac.uk/ws/files/152520269/Emanueli2017Bioinformbtx477.pdf
https://research-information.bris.ac.uk/ws/files/152520269/Emanueli2017Bioinformbtx477.pdf
Autor:
Dumas, M-E, Rothwell, AR, Hoyles, L, Aranias, T, Chilloux, J, Calderari, S, Noll, EM, Péan, N, Boulangé, CL, Blancher, C, Barton, RH, Gu, Q, Fearnside, JF, Deshayes, C, Hue, C, Scott, J, Nicholson, JK, Gauguier, D
Publikováno v:
Cell Reports
Cell Reports, 2017, 20 (1), pp.136-148. ⟨10.1016/j.celrep.2017.06.039⟩
Cell Reports, Elsevier Inc, 2017, 20 (1), pp.136-148. ⟨10.1016/j.celrep.2017.06.039⟩
Cell Reports, Vol 20, Iss 1, Pp 136-148 (2017)
Cell Reports, 2017, 20 (1), pp.136-148. ⟨10.1016/j.celrep.2017.06.039⟩
Cell Reports, Elsevier Inc, 2017, 20 (1), pp.136-148. ⟨10.1016/j.celrep.2017.06.039⟩
Cell Reports, Vol 20, Iss 1, Pp 136-148 (2017)
Summary The influence of the gut microbiome on metabolic and behavioral traits is widely accepted, though the microbiome-derived metabolites involved remain unclear. We carried out untargeted urine 1H-NMR spectroscopy-based metabolic phenotyping in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8ade711b283e249f5aa41ce1fbcf5134
https://ora.ox.ac.uk/objects/uuid:bb30e12a-8ecc-4451-9fa6-5cfb552927b3
https://ora.ox.ac.uk/objects/uuid:bb30e12a-8ecc-4451-9fa6-5cfb552927b3
Publikováno v:
IUNS 21st ICN International Congress of Nutrition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1032::5c266cd0a2166631f45ba2905dca1e33
http://hdl.handle.net/10044/1/64043
http://hdl.handle.net/10044/1/64043
Autor:
Hoyles, L, Fernández-Real, JM, Federici, M, Serino, M, Azalbert, V, Blasco, V, Abbott, J, Barton, RH, Puig, J, Xifra, G, Ricart, W, Woodbridge, M, Tomlinson, C, Cardellini, M, Davato, F, Cardolini, I, Porzio, O, Gentilieschi, P, Lopez, F, Foufelle, F, Postic, C, Butcher, SA, Holmes, E, Nicholson, JK, Burcelin, R, Dumas, ME
Publikováno v:
Exploring Human Host-Microbiome Interactions in Health and Disease
Non-alcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease, increasing in worldwide prevalence as a result of the obesity epidemic. It manifests in hepatic cells as steatosis with or without lobular inflammati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1032::ce72d63487682d34ad67a66c505df308
http://hdl.handle.net/10044/1/52673
http://hdl.handle.net/10044/1/52673
The need for rapid and efficient high throughput metabolic phenotyping (metabotyping) in metabolomic/metabonomic studies often requires compromises to be made between analytical speed and metabolome coverage. Here the effect of column length (150, 75
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1032::caa1e92cd5a03ccb0f7227a8d2735932
http://hdl.handle.net/10044/1/49269
http://hdl.handle.net/10044/1/49269
Autor:
Hoyles, L, Fernández-Real, JM, Federici, M, Serino, M, Azalbert, V, Blasco, V, Abbott, J, Barton, RH, Puig, J, Xifra, G, Ricart, W, Woodbridge, M, Tomlinson, C, Cardellini, M, Davato, F, Cardolini, I, Porzio, O, Gentilieshci, P, Lopez, F, Foufelle, F, Postic, C, Butcher, SA, Holmes, E, Nicholson, JK, Burcelin, R, Dumas, MD
Publikováno v:
Gut Microbiota for Health World Summit 2017
International Scientific Association for Probiotics and Prebiotics
International Scientific Association for Probiotics and Prebiotics
Objectives: To integrate metagenomic (faecal microbiome), transcriptomic, metabonomic and clinical data to evaluate the contribution of the gut microbiome to the molecular phenome (hepatic transcriptome, plasma and urine metabonome) of non-alcoholic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::68ea3d62800e80c2a60007489b71c8f7
http://hdl.handle.net/10044/1/52674
http://hdl.handle.net/10044/1/52674
Autor:
Posma, JM, Garcia Perez, I, Heaton, JC, Burdisso, P, Mathers, JC, Draper, J, Lewis, M, Lindon, JC, Frost, G, Holmes, E, Nicholson, JK
A major purpose of exploratory metabolic profiling is for the identification of molecular species that are statistically associated with specific biological or medical outcomes; unfortunately the structure elucidation process of unknowns is often a m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1032::5573a5fde8ce0708877f8a38b9055668
http://hdl.handle.net/10044/1/45084
http://hdl.handle.net/10044/1/45084