Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Nichole Vansell"'
Autor:
Mihály Hajós, William E. Hoffman, John F. Harms, Mary Piotrowski, Christopher J. Schmidt, Eric P. Arnold, Robin J. Kleiman, Edward X. Yang, Adam Ogden, Patricia A. Seymour, Jiemin Lu, Ethan Lawrence Fisher, Nichole Vansell, Patrick Robert Verhoest, Jayvardhan Pandit, Zhijun Kang, Hirokazu Ueno, John M. Humphrey, Bethany L. Kormos, Dina McGinnis, Thomas Allen Chappie, Noha Maklad, Laura McDowell, Cheng Chang, Rebecca E. O’Connor, Chewah Lee, Tracey Boyden, Christopher J. O’Donnell, Christopher John Helal
Publikováno v:
Journal of medicinal chemistry. 61(3)
Computational modeling was used to direct the synthesis of analogs of previously reported phosphodiesterase 2A (PDE2A) inhibitor 1 with an imidazotriazine core to yield compounds of significantly enhanced potency. The analog PF-05180999 (30) was subs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::408cc7b21c310fe120ce681146fe8fb5
https://pubmed.ncbi.nlm.nih.gov/29293004
https://pubmed.ncbi.nlm.nih.gov/29293004
Autor:
Yuhua, Zhang, Jun, Xu, Jeremy, Levin, Martin, Hegen, Guangde, Li, Heidi, Robertshaw, Fionula, Brennan, Terri, Cummons, Dave, Clarke, Nichole, Vansell, Cheryl, Nickerson-Nutter, Dauphine, Barone, Ken, Mohler, Roy, Black, Jerry, Skotnicki, Jay, Gibbons, Marc, Feldmann, Philip, Frost, Glenn, Larsen, Lih-Ling, Lin
Publikováno v:
The Journal of Pharmacology and Experimental Therapeutics; April 2004, Vol. 309 Issue: 1 p348-55, 8p