Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Nichole Orr‐Burks"'
Autor:
Lorena C S Chaves, Nichole Orr-Burks, Daryll Vanover, Varun V Mosur, Sarah R Hosking, Pramod Kumar E K, Hyeyoon Jeong, Younghun Jung, José A F Assumpção, Hannah E Peck, Sarah L Nelson, Kaitlyn N Burke, McKinzie A Garrison, Robert A Arthur, Henry Claussen, Nicholas S Heaton, Eric R Lafontaine, Robert J Hogan, Chiara Zurla, Philip J Santangelo
Publikováno v:
PLoS Pathogens, Vol 20, Iss 7, p e1012345 (2024)
The CRISPR-Cas13 system has been proposed as an alternative treatment of viral infections. However, for this approach to be adopted as an antiviral, it must be optimized until levels of efficacy rival or exceed the performance of conventional approac
Externí odkaz:
https://doaj.org/article/ff2b71e5f2c14cc889ed30f7de84cd2e
Autor:
Jackelyn Murray, David E. Martin, Sarah Hosking, Nichole Orr-Burks, Robert J. Hogan, Ralph A. Tripp
Publikováno v:
Viruses, Vol 16, Iss 1, p 152 (2024)
Avian influenza (AI) viruses cause infection in birds and humans. Several H5N1 and H7N9 variants are highly pathogenic avian influenza (HPAI) viruses. H5N1 is a highly infectious bird virus infecting primarily poultry, but unlike other AIs, H5N1 also
Externí odkaz:
https://doaj.org/article/c244c4c82587489cad1b76cb4dbc4d7e
Autor:
Daryll Vanover, Chiara Zurla, Hannah E. Peck, Nichole Orr‐Burks, Jae Yeon Joo, Jackelyn Murray, Nathan Holladay, Ryan A. Hobbs, Younghun Jung, Lorena C. S. Chaves, Laura Rotolo, Aaron W. Lifland, Alicia K. Olivier, Dapeng Li, Kevin O. Saunders, Gregory D. Sempowski, James E. Crowe Jr., Barton F. Haynes, Eric R. Lafontaine, Robert J. Hogan, Philip J. Santangelo
Publikováno v:
Advanced Science, Vol 9, Iss 34, Pp n/a-n/a (2022)
Abstract Despite the success of severe acute respiratory syndrome coronavirus‐2 (SARS‐CoV‐2) vaccines, there remains a clear need for new classes of preventatives for respiratory viral infections due to vaccine hesitancy, lack of sterilizing im
Externí odkaz:
https://doaj.org/article/ecf03feec815403cb0b70263213107be
Publikováno v:
PLoS ONE, Vol 16, Iss 10 (2021)
Influenza viruses cause respiratory tract infections and substantial health concerns. Infection may result in mild to severe respiratory disease associated with morbidity and some mortality. Several anti-influenza drugs are available, but these agent
Externí odkaz:
https://doaj.org/article/db9893bc49e642808a469b76e5972373
Autor:
Nichole Orr-Burks, Jackelyn Murray, Weilin Wu, Carl D. Kirkwood, Kyle V. Todd, Les Jones, Abhijeet Bakre, Houping Wang, Baoming Jiang, Ralph A. Tripp
Publikováno v:
Vaccine: X, Vol 3, Iss , Pp - (2019)
Background: Rotavirus (RV) is a leading cause of severe gastroenteritis globally and can cause substantial morbidity associated with gastroenteritis in children
Externí odkaz:
https://doaj.org/article/7da58cd23db742e0b19653aa249138f5
Autor:
Jackelyn Murray, Kyle V Todd, Abhijeet Bakre, Nichole Orr-Burks, Les Jones, Weilin Wu, Ralph A Tripp
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188333 (2017)
Using genome-wide small interfering RNA (siRNA) screens for poliovirus, influenza A virus and rotavirus, we validated the top 6 gene hits PV, RV or IAV to search for host genes that when knocked-down (KD) enhanced virus permissiveness and replication
Externí odkaz:
https://doaj.org/article/22c465276bd349eabcdba16cd58ffb27
Autor:
Ashley C. Beavis, Zhuo Li, Kelsey Briggs, María Cristina Huertas-Díaz, Elizabeth R. Wrobel, Maria Najera, Dong An, Nichole Orr-Burks, Jackelyn Murray, Preetish Patil, Jiachen Huang, Jarrod Mousa, Linhui Hao, Tien-Ying Hsiang, Michael Gale, Stephen B. Harvey, S. Mark Tompkins, Robert Jeffrey Hogan, Eric R. Lafontaine, Hong Jin, Biao He
Publikováno v:
bioRxiv
Immunization with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines has greatly reduced coronavirus disease 2019 (COVID-19)-related deaths and hospitalizations, but waning immunity and the emergence of variants capable of immune e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b64a12ff9c68c36a27e71c89d2365fbd
https://pubmed.ncbi.nlm.nih.gov/35702147
https://pubmed.ncbi.nlm.nih.gov/35702147
Publikováno v:
The Journal of General Virology
Influenza virus causes seasonal epidemics and sporadic pandemics resulting in morbidity, mortality, and economic losses worldwide. Understanding how to regulate influenza virus replication is important for developing vaccine and therapeutic strategie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c92351d600b8aa4cf263805207ac0b
https://doi.org/10.1099/jgv.0.001691
https://doi.org/10.1099/jgv.0.001691
Autor:
Laura Rotolo, Daryll Vanover, Nicholas C. Bruno, Hannah E. Peck, Chiara Zurla, Jackelyn Murray, Richard K. Noel, Laura O’Farrell, Mariluz Araínga, Nichole Orr-Burks, Jae Yeon Joo, Lorena C. S. Chaves, Younghun Jung, Jared Beyersdorf, Sanjeev Gumber, Ricardo Guerrero-Ferreira, Santiago Cornejo, Merrilee Thoresen, Alicia K. Olivier, Katie M. Kuo, James C. Gumbart, Amelia R. Woolums, Francois Villinger, Eric R. Lafontaine, Robert J. Hogan, M. G. Finn, Philip J. Santangelo
Publikováno v:
Nature materials.
Messenger RNA has now been used to vaccinate millions of people. However, the diversity of pulmonary pathologies, including infections, genetic disorders, asthma and others, reveals the lung as an important organ to directly target for future RNA the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb7ec4891651d0788c7b5a29165e8651
https://pubmed.ncbi.nlm.nih.gov/36443576
https://pubmed.ncbi.nlm.nih.gov/36443576
Publikováno v:
Journal of Virology
Influenza epidemics result in morbidity and mortality each year. Vaccines are the most effective preventive measure but require annual reformulation, since a mismatch of vaccine strains can result in vaccine failure.
Influenza virus causes epide
Influenza virus causes epide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abca04c5958a5d9cc83f8efea6524d52
https://doi.org/10.1128/jvi.02410-20
https://doi.org/10.1128/jvi.02410-20