Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Nichole Lewis"'
Autor:
Kelly M. Bush, Rachel Herndon Klein, Nichole Lewis, Paul S. Knoepfler, Vanessa Cervantes, Mirna Lechpammer, Kuang Yui Chen, Aasim Naqvi, Angel M. Carcaboso
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-15 (2020)
Communications biology, vol 3, iss 1
Communications Biology
Communications biology, vol 3, iss 1
Communications Biology
Histone H3.3 mutations are a hallmark of pediatric gliomas, but their core oncogenic mechanisms are not well-defined. To identify major effectors, we used CRISPR-Cas9 to introduce H3.3K27M and G34R mutations into previously H3.3-wildtype brain cells,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf23000072b959b2350f5158849985bf
http://link.springer.com/article/10.1038/s42003-020-1076-0
http://link.springer.com/article/10.1038/s42003-020-1076-0
Publikováno v:
Neuro Oncol
Alterations in histone H3.3 are common driver mutations in high-grade pediatric gliomas, but the central oncogenic mechanisms remain an open question. To identify important mutant H3.3 effectors, we used CRISPR-Cas9 to precisely introduce H3.3 K27M a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c04631b7d0324f7b9a07aff20e55eb40
https://europepmc.org/articles/PMC6847561/
https://europepmc.org/articles/PMC6847561/
Autor:
Vanessa Cervantes, Paul S. Knoepfler, Michael Chen, Angel M. Carcaboso, Aasim Naqvi, Nichole Lewis, Kelly M. Bush, Rachel Herndon Klein
Pediatric high-grade gliomas often contain mutations in the H3F3A gene encoding the histone variant H3.3 and more rarely in canonical histone H3 family genes, a feature distinguishing them from adult gliomas. To define specific functionally significa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::931b001a2f0ae191c9b7215b00bd6ac2
https://europepmc.org/articles/PMC6477327/
https://europepmc.org/articles/PMC6477327/
Autor:
H. Leon Pachter, Manish Parikh, Christine J. Ren, George Fielding, Eleny Romanos, Nichole Lewis, Patricia Ayoung-Chee
Publikováno v:
Journal of the American College of Surgeons. 205(5)
Bariatric operation is the most effective treatment for diabetes mellitus in the morbidly obese. The purpose of this study is to compare the rate of resolution of diabetes mellitus after three common laparoscopic bariatric procedures: laparoscopic ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5a0abcf9e450f4fb8d374c825803f1b
https://pubmed.ncbi.nlm.nih.gov/17964437
https://pubmed.ncbi.nlm.nih.gov/17964437
Publikováno v:
Journal of the American College of Surgeons. 203:S10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc3b5954d14b23a04d341fbe35ab944e
https://doi.org/10.1016/j.jamcollsurg.2006.05.022
https://doi.org/10.1016/j.jamcollsurg.2006.05.022