Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Nichole D. Bond"'
Publikováno v:
International Journal of Biological Sciences
Retrospective and prospective studies show that lean mass or strength is positively associated with metabolic health. Mice deficient in myostatin, a growth factor that negatively regulates skeletal muscle mass, have increased muscle and body weights
Publikováno v:
Adipocyte
Skeletal muscle insulin resistance is a predictor of the development of type 2 diabetes and maintenance of adequate muscle glucose disposal in muscle may help to prevent diabetes. Lipodystrophy is a type of diabetes caused by a reduction of white adi
Autor:
Oksana Gavrilova, William Jou, Alexandra C. McPherron, Tingqing Guo, Jennifer Portas, Nichole D. Bond
Publikováno v:
Diabetes
Lipodystrophies are characterized by a loss of white adipose tissue, which causes ectopic lipid deposition, peripheral insulin resistance, reduced adipokine levels, and increased food intake (hyperphagia). The growth factor myostatin (MSTN) negativel
Publikováno v:
genesis. 44:396-400
The remodeling of the larval fat body is observed in many insects during metamorphosis, but little is known about the physiological importance or the regulation of this process. In Drosophila melanogaster, fat-body remodeling involves the dissociatio
Publikováno v:
Comparative biochemistry and physiology. Part A, Molecularintegrative physiology. 157(4)
In holometabolous insects, the steroid hormone 20-hydroxyecdysone (20E), in coordination with juvenile hormone, regulates the major developmental events that promote larval development and the transition from the larval to the pupal stage. Intimately
Autor:
Deborah K. Hoshizaki, Melanie A. Ayerh, Nichole D. Bond, Marsha K. Bernardo, Craig T. Woodard, Kathryn A. Gorski, Archana Nelliot
Publikováno v:
Developmental Biology. (2):286-296
During metamorphosis, holometabolous insects eliminate obsolete larval tissues via programmed cell death. In contrast, tissues required for further development are retained and often remodeled to meet the needs of the adult fly. The larval fat body i
Publikováno v:
BMC Proceedings, Vol 6, Iss Suppl 3, p P7 (2012)
BMC Proceedings
BMC Proceedings
Background Skeletal muscle is a key peripheral metabolic tissue: Muscle is responsible for most insulin-stimulated glucose uptake, and muscle insulin resistance is the first defect detectable in the development of type 2 diabetes. Recent studies show