Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Nichole Charlton-Kachigian"'
Publikováno v:
Journal of Biological Chemistry. 279:32913-32923
Msx2 promotes osteogenic lineage allocation from mesenchymal progenitors but inhibits terminal differentiation demarcated by osteocalcin (OC) gene expression. Msx2 inhibits OC expression by targeting the fibroblast growth factor responsive element (O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::264c5f7040efaffa602d18f2d0d7b9e5
https://doi.org/10.1074/jbc.m314098200
https://doi.org/10.1074/jbc.m314098200
Autor:
Jian Su Shao, Joyce M. Pingsterhaus, Arleen P. Loewy, Nichole Charlton-Kachigian, Su Li Cheng, Dwight A. Towler
Publikováno v:
The Journal of clinical investigation. 115(5)
In diabetic LDLR-/- mice, an ectopic BMP2-Msx2 gene regulatory program is upregulated in association with vascular calcification. We verified the procalcific actions of aortic Msx2 expression in vivo. CMV-Msx2 transgenic (CMV-Msx2Tg(+)) mice expresse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e170e233e4aa95c0746fb3bff832d649
https://pubmed.ncbi.nlm.nih.gov/15841209
https://pubmed.ncbi.nlm.nih.gov/15841209
Publikováno v:
The Journal of biological chemistry. 278(50)
Cardiovascular calcification is a common consequence of diabetes. High fat diets induce diabetes and arterial calcification in male low density lipoprotein receptor (LDLR) -/- mice; calcification occurs via Msx2 signaling that promotes the osteogenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e432472f2aac8b36a983e2330b874e8
https://pubmed.ncbi.nlm.nih.gov/14504275
https://pubmed.ncbi.nlm.nih.gov/14504275
Autor:
Clay F. Semenkovich, Nichole Charlton-Kachigian, Dwight A. Towler, Arleen P. Loewy, Jian Su Shao, Miri Bidder
Publikováno v:
The Journal of biological chemistry. 277(46)
The expression of the matrix cytokine osteopontin (OPN) is up-regulated in aortic vascular smooth muscle cells (VSMCs) by diabetes. OPN expression in cultured VSMCs is reciprocally regulated by glucose and 2-deoxyglucose (2-DG; inhibitor of cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::281d83226d22e14499f3630e1d7a96e6
https://pubmed.ncbi.nlm.nih.gov/12200434
https://pubmed.ncbi.nlm.nih.gov/12200434
Autor:
Nichole Charlton-Kachigian, Dwight A. Towler, David M. Willis, Arleen P. Loewy, David M. Ornitz, Jian-Su Shao
Publikováno v:
The Journal of biological chemistry. 277(40)
We previously described an osteocalcin (OC) fibroblast growth factor (FGF) response element (FRE) DNA binding activity as a target of Msx2 transcriptional regulation. We now identify Ku70, Ku80, and Tbdn100, a variant of Tubedown-1, as constituents o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe5e3ee011e20d1ab3c1cbe028e58580
https://pubmed.ncbi.nlm.nih.gov/12145306
https://pubmed.ncbi.nlm.nih.gov/12145306