Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Nichole Carlson"'
Autor:
Michaeleen Burns, Laura Landry, David Mills, Jillian M. Blueford, Nichole Carlson, Ayelet Talmi
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/72bb2b0012dc4af09523e8cba8a10e81
Autor:
Michaeleen Burns, Laura Landry, David Mills, Nichole Carlson, Jillian M. Blueford, Ayelet Talmi
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
The COVID-19 pandemic devastated public welfare worldwide, bringing excess deaths connected to causes such as homicide, substance abuse, and heart disease. In the U.S., these mortality increases disproportionally impacted communities of color and con
Externí odkaz:
https://doaj.org/article/f991958367c745f2b7bd5fde3b169ae3
Autor:
Nichole Carlson
Publikováno v:
Science Translational Medicine. 2
Is "bio-creep" a problem in your clinical trial? Clinical trial designs vary from traditional superiority trials, in which the goal is to show that a new treatment works better—is more efficacious—than the existing treatment, to noninferiority tr
Autor:
Nichole Carlson
Publikováno v:
Science Translational Medicine. 2
Everyone’s looking for biomarkers. Defined as any physiologic or anatomical measurement of a quantity related to a disease process, biomarkers are needed to find therapies for complex diseases. Examples include blood cholesterol concentrations, bra
Autor:
Nichole Carlson
Publikováno v:
Science Translational Medicine. 2
Until recently, genetic and environmental causes of disease were studied independently. But now a body of research has revealed that for some diseases with genetic components, context is everything. In fact, certain diseases show genetic associations
Autor:
Nichole Carlson
Publikováno v:
Science Translational Medicine. 2
The recent political milestone of enacting health care reform in the United States has put the field of comparative effectiveness research (CER) front and center. CER—research comparing different health care models for preventing, diagnosing, treat
Autor:
Nichole Carlson
Publikováno v:
Science Translational Medicine. 2
New research technology can lead to new scientific insight—as long as it is not prohibitively expensive. Use of the best design parameters can help control costs. One such technology is next-generation sequencing, which can help to decipher the rol
Autor:
Nichole Carlson
Publikováno v:
Science Translational Medicine. 2
Linear regression—a model of the relationship between an outcome in a study and one or more measures of interest—is one of the most popular statistical analysis techniques and is applied in a wide range of research studies. For the results of a l
Autor:
Nichole Carlson
Publikováno v:
Science Translational Medicine. 2
Most researchers have suffered through the following challenge: A new analytic approach is published that seems applicable to a scientist’s own research. Thus, that scientist wants to apply the approach and, if it is a data analysis method, first t
Autor:
Nichole Carlson
Publikováno v:
Science Translational Medicine. 2
Knowledge is power. This is especially true for research projects in which incorporating existing knowledge into a new data analysis can increase the power of the study. Bayesian analysis is one approach that allows for adding what we already know in