Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nichole A. Reynolds"'
Autor:
Joseph D. Ho, Betty Chau, Logan Rodgers, Frances Lu, Kelly L. Wilbur, Keith A. Otto, Yanyun Chen, Min Song, Jonathan P. Riley, Hsiu-Chiung Yang, Nichole A. Reynolds, Steven D. Kahl, Anjana Patel Lewis, Christopher Groshong, Russell E. Madsen, Kris Conners, Jayana P. Lineswala, Tarun Gheyi, Melbert-Brian Decipulo Saflor, Matthew R. Lee, Jordi Benach, Kenton A. Baker, Chahrzad Montrose-Rafizadeh, Michael J. Genin, Anne R. Miller, Chafiq Hamdouchi
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
GPR40 is a G-protein coupled receptor that binds to free fatty acids, mediating insulin and incretin secretion. Here, the authors present the crystal structure of human GPR40 with an agonist bound to an allosteric site located near the lipid-rich reg
Externí odkaz:
https://doaj.org/article/5d745f39e74e44df919e15e9433e1c33
Autor:
Jacob R. Enriquez, Carey L. Watson, Heather A. McCauley, Nichole A. Reynolds, Hsiu-Chiung Yang, Katie L. Sinagoga, Jorge O. Múnera, James M. Wells, Michael A. Helmrath
Enteroendocrine cells (EECs) are a minor cell population in the intestine yet they play a major role in digestion, satiety and nutrient homeostasis. Recently developed human intestinal organoid models include EECs, but their rarity makes it difficult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b39b72287aabaec973a8abcecef0f048
https://europepmc.org/articles/PMC6198470/
https://europepmc.org/articles/PMC6198470/
Autor:
Min Song, Christopher Groshong, Frances Lu, Yanyun Chen, Steven D. Kahl, Chahrzad Montrose-Rafizadeh, Jayana Pankaj Lineswala, Melbert-Brian Decipulo Saflor, Nichole A. Reynolds, Michaël Genin, Anjana Patel Lewis, Tarun Gheyi, Hsiu-Chiung Yang, Russell E. Madsen, Betty Chau, Chafiq Hamdouchi, Matthew R. Lee, Kenton A. Baker, Anne Reifel Miller, Joseph D. Ho, Keith A. Otto, Kelly L. Wilbur, K. Conners, Jordi Benach, Jonathan P. Riley, Logan Rodgers
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature Communications
Nature Communications
Activation of free fatty acid receptor 1 (GPR40) by synthetic partial and full agonists occur via distinct allosteric sites. A crystal structure of GPR40-TAK-875 complex revealed the allosteric site for the partial agonist. Here we report the 2.76-Å
Autor:
Hsiu-Chiung Yang, Jenny Tong, Nichole A. Reynolds, Marian Mosior, Ming-Shang Kuo, Travis Shockley, Yanyun Chen
Publikováno v:
The FASEB Journal. 29
Ghrelin (AG) is the only known orexigenic peptide in human and rodents. It is converted from its precursor, unacylated ghrelin (UAG), to the biologically active peptide, acylghrelin. Two independent groups (Yang et al., 2008; Gutierrez 2009) using di
Autor:
Don Jon Summerlin, Eric T. Everett, Shokri Radpour, Samuel Campbell, James K. Hartsfield, Mark Langer, Paul D. Righi, Arden G. Christen, Edward C. Weisberger, George J. Eckert, Armando G. Amador, Nichole A. Reynolds
Publikováno v:
Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology. 93:440-445
Objective. The objective was to determine the prevalence of the polymorphisms of the microsomal epoxide hydrolase (Ephx1), glutathione S-transferase µ1 (GSTM1), θ1 (GSTT1), and π1 (GSTP1) genes in patients with oropharyngeal carcinoma. Study desig
Autor:
C. Kantmann, Eric T. Everett, J. Sullivan, Nichole A. Reynolds, Esperanza A. Martinez-Mier, M.A.K. McHenry, J.M. Warrick, George K. Stookey, Hafsteinn Eggertsson
Publikováno v:
Journal of dental research. 81(11)
Concurrent with the decline in dental caries has been an increase in the prevalence of dental fluorosis, a side-effect of exposure to greater than optimal levels of fluoride during amelogenesis. The mechanisms that underlie the pathogenesis of dental