Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Nicholas van Bruggen"'
Autor:
Ganesh Kolumam, Mark Z. Chen, Raymond Tong, Jose Zavala-Solorio, Lance Kates, Nicholas van Bruggen, Jed Ross, Shelby K. Wyatt, Vineela D. Gandham, Richard A.D. Carano, Diana Ronai Dunshee, Ai-Luen Wu, Benjamin Haley, Keith Anderson, Søren Warming, Xin Y. Rairdan, Nicholas Lewin-Koh, Yingnan Zhang, Johnny Gutierrez, Amos Baruch, Thomas R. Gelzleichter, Dale Stevens, Sharmila Rajan, Travis W. Bainbridge, Jean-Michel Vernes, Y. Gloria Meng, James Ziai, Robert H. Soriano, Matthew J. Brauer, Yongmei Chen, Scott Stawicki, Hok Seon Kim, Laëtitia Comps-Agrar, Elizabeth Luis, Christoph Spiess, Yan Wu, James A. Ernst, Owen P. McGuinness, Andrew S. Peterson, Junichiro Sonoda
Publikováno v:
EBioMedicine, Vol 2, Iss 7, Pp 730-743 (2015)
Dissipating excess calories as heat through therapeutic stimulation of brown adipose tissues (BAT) has been proposed as a potential treatment for obesity-linked disorders. Here, we describe the generation of a humanized effector-less bispecific antib
Externí odkaz:
https://doaj.org/article/acbf9281cbc1473db78d9eaceadaf5d7
Autor:
Yunzhou Shi, Jason Oeh, Jeffrey Eastham-Anderson, Sharon Yee, David Finkle, Franklin V. Peale, Jr, Jed Ross, Maj Hedehus, Nicholas van Bruggen, Rayna Venook, Sarajane Ross, Deepak Sampath, Richard A.D. Carano
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 15, Iss 11, Pp 1241-1250 (2013)
Quantifying oxygenation in viable tumor remains a major obstacle toward a better understanding of the tumor microenvironment and improving treatment strategies. Current techniques are often complicated by tumor heterogeneity. Herein, a novel in vivo
Externí odkaz:
https://doaj.org/article/7914fc373e614f65bd3e6d578cf2491d
Autor:
Alvin Gogineni, Maresa Caunt, Ailey Crow, Chingwei V Lee, Germaine Fuh, Nicholas van Bruggen, Weilan Ye, Robby M Weimer
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68755 (2013)
Tumor-associated lymphatics are postulated to provide a transit route for disseminating metastatic cells. This notion is supported by preclinical findings that inhibition of pro-lymphangiogenic signaling during tumor development reduces cell spread t
Externí odkaz:
https://doaj.org/article/a652bd60748b455490ab8d1771e992ac
Autor:
Gordon C. Jayson, Nicholas van Bruggen, Napoleone Ferrara, Olivia del Puerto, Paula Thornton, Jurjees Hasan, Karen Davies, Giovanni A. Buonaccorsi, Sarajane Ross, Tim C. Cao, Xiumin Wu, Glenn J. Pacheco, Mary Ann T. Go, Hani Bou Reslan, Sue Cheung, Lynn Hope, Caleb Roberts, Yvonne Watson, Claire L. Mitchell, Michel Friesenhahn, Franklin V. Peale, Chris J. Rose, Geoff J.M. Parker, Alan Jackson, Calvin C.K. Ho, Jed Ross, Andrew R. Clamp, Richard A.D. Carano, James P.B. O'Connor
Supplementary Data from Quantifying Antivascular Effects of Monoclonal Antibodies to Vascular Endothelial Growth Factor: Insights from Imaging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c044431327581809ffe331a2b4700f9
https://doi.org/10.1158/1078-0432.22440574.v1
https://doi.org/10.1158/1078-0432.22440574.v1
Autor:
Gordon C. Jayson, Nicholas van Bruggen, Napoleone Ferrara, Olivia del Puerto, Paula Thornton, Jurjees Hasan, Karen Davies, Giovanni A. Buonaccorsi, Sarajane Ross, Tim C. Cao, Xiumin Wu, Glenn J. Pacheco, Mary Ann T. Go, Hani Bou Reslan, Sue Cheung, Lynn Hope, Caleb Roberts, Yvonne Watson, Claire L. Mitchell, Michel Friesenhahn, Franklin V. Peale, Chris J. Rose, Geoff J.M. Parker, Alan Jackson, Calvin C.K. Ho, Jed Ross, Andrew R. Clamp, Richard A.D. Carano, James P.B. O'Connor
CCR Translation for the Article from Quantifying Antivascular Effects of Monoclonal Antibodies to Vascular Endothelial Growth Factor: Insights from Imaging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b15c08ae1c058cb6d4224af3e1f19d1
https://doi.org/10.1158/1078-0432.22440577
https://doi.org/10.1158/1078-0432.22440577
Autor:
Gordon C. Jayson, Nicholas van Bruggen, Napoleone Ferrara, Olivia del Puerto, Paula Thornton, Jurjees Hasan, Karen Davies, Giovanni A. Buonaccorsi, Sarajane Ross, Tim C. Cao, Xiumin Wu, Glenn J. Pacheco, Mary Ann T. Go, Hani Bou Reslan, Sue Cheung, Lynn Hope, Caleb Roberts, Yvonne Watson, Claire L. Mitchell, Michel Friesenhahn, Franklin V. Peale, Chris J. Rose, Geoff J.M. Parker, Alan Jackson, Calvin C.K. Ho, Jed Ross, Andrew R. Clamp, Richard A.D. Carano, James P.B. O'Connor
Purpose: Little is known concerning the onset, duration, and magnitude of direct therapeutic effects of anti–vascular endothelial growth factor (VEGF) therapies. Such knowledge would help guide the rational development of targeted therapeutics from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24828396fa0d9bf616db702d9622adeb
https://doi.org/10.1158/1078-0432.c.6517882.v1
https://doi.org/10.1158/1078-0432.c.6517882.v1
Autor:
Napoleone Ferrara, Franklin V. Peale, Nicholas Van Bruggen, William F. Forrest, Jeffrey Eastham-Anderson, Linda Hall, Navneet Pal, Marcin Kowanetz, Xiumin Wu, Jed Ross, Nina Korsisaari
Purpose: Multiple endocrine neoplasia type 1 (MEN1) is defined clinically by the combined occurrence of multiple tumors, typically of the parathyroid glands, pancreatic islet cells, and anterior pituitary gland. A mouse model with a heterozygous dele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4ad9f1da6745824085a2fe0a7d60949
https://doi.org/10.1158/1078-0432.c.6518419.v1
https://doi.org/10.1158/1078-0432.c.6518419.v1
Autor:
Napoleone Ferrara, Franklin V. Peale, Nicholas Van Bruggen, William F. Forrest, Jeffrey Eastham-Anderson, Linda Hall, Navneet Pal, Marcin Kowanetz, Xiumin Wu, Jed Ross, Nina Korsisaari
Supplementary Figures S1-S2 from Blocking Vascular Endothelial Growth Factor-A Inhibits the Growth of Pituitary Adenomas and Lowers Serum Prolactin Level in a Mouse Model of Multiple Endocrine Neoplasia Type 1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fd19138f0441fb03d8e0b897cb28a05
https://doi.org/10.1158/1078-0432.22441330
https://doi.org/10.1158/1078-0432.22441330
Autor:
Saul A. Villeda, Ganesh Kolumam, Ilya Soifer, Wendy Cedron-Craft, Pedro Sousa-Victor, Deepak A. Lamba, Joana Neves, Rebeccah Riley, Heinrich Jasper, Nicholas van Bruggen, P. Britten Ventura, Chen-Yu Liao
Publikováno v:
Nature metabolism
Aging is accompanied by altered intercellular communication, deregulated metabolic function, and inflammation. Interventions that restore a youthful state delay or reverse these processes, prompting the search for systemic regulators of metabolic and
Autor:
Diana Ronai Dunshee, Jose Zavala-Solorio, Hok Seon Kim, Sharmila Rajan, Yongmei Chen, James A. Ernst, Elizabeth Luis, Ai-Luen Wu, Robert Soriano, Ganesh Kolumam, Amos Baruch, Mark Z. Chen, Raymond K. Tong, Shelby K. Wyatt, Richard A.D. Carano, Christoph Spiess, Owen P. McGuinness, Jean-Michel Vernes, Andrew S. Peterson, Søren Warming, Keith R. Anderson, Xin Y. Rairdan, Junichiro Sonoda, Matthew J. Brauer, Scott Stawicki, Benjamin Haley, Laetitia Comps-Agrar, Jed Ross, Y. Gloria Meng, Johnny Gutierrez, James Ziai, Thomas Gelzleichter, Travis W. Bainbridge, Nicholas Lewin-Koh, Yan Wu, Nicholas van Bruggen, Vineela D. Gandham, Lance Kates, Yingnan Zhang, Dale Stevens
Publikováno v:
EBioMedicine, Vol 2, Iss 7, Pp 730-743 (2015)
EBioMedicine
EBioMedicine
Dissipating excess calories as heat through therapeutic stimulation of brown adipose tissues (BAT) has been proposed as a potential treatment for obesity-linked disorders. Here, we describe the generation of a humanized effector-less bispecific antib