Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Nicholas Zezza"'
Autor:
Shirley Y. Hill, Jeannette L. Wellman, Nicholas Zezza, Stuart R. Steinhauer, Vinod Sharma, Brian Holmes
Publikováno v:
Behavioral Sciences, Vol 12, Iss 10, p 347 (2022)
Association between familial loading for alcohol use disorders (AUD) and event-related potentials (ERPs) suggests a genetic basis for these oscillations though much less is known about epigenetic pathways influenced by environmental variation. Early
Externí odkaz:
https://doaj.org/article/4924822b0d6a41aba4b190c6dc2ce470
Cross-generational effects of alcohol dependence in humans on HRAS and TP53 methylation in offspring
Publikováno v:
Epigenomics. 9:1189-1203
Aim: We hypothesized that cross-generational effects of alcohol exposure could alter DNA methylation and expression of the HRAS oncogene and TP53 tumor suppressor gene that drive cancer development. Methods: DNA methylation of the HRAS and TP53 genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fd31160712f5cf3e3a4b46caab48f49
https://doi.org/10.2217/epi-2017-0052
https://doi.org/10.2217/epi-2017-0052
Autor:
Scott Stiffler, Brian Holmes, Sarah Lichenstein, Bobby L. Jones, Jessica W. O'Brien, Shirley Y. Hill, Nicholas Zezza
Publikováno v:
Pharmacogenomics. 15:1311-1321
Aim: Familial loading for alcohol dependence (AD) and variation in genes reported to be associated with AD or BMI were tested in a longitudinal study. Materials & methods: Growth curve analyses of BMI data collected at approximately yearly intervals
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0c38babf407218cfd9ec669a6c0665a
https://doi.org/10.2217/pgs.14.86
https://doi.org/10.2217/pgs.14.86
Publikováno v:
Open journal of genetics
Background: A previous genome-wide linkage study of alcohol dependence in multiplex families found a suggestive linkage result for a region on Chromosome 1 near microsatellite markers D1S196 and D1S2878. The KIAA0040 gene has been mapped to this regi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebe51fcbdacd18f817638c536d3745b4
https://doi.org/10.4236/ojgen.2013.34027
https://doi.org/10.4236/ojgen.2013.34027
Publikováno v:
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. :445-455
A previous genome-wide linkage study of alcohol dependence (AD) in multiplex families found a suggestive linkage result for a region on Chromosome 1 near microsatellite markers D1S196 and D1S2878. The ASTN1 gene is in this region, a gene previously r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86a933a7de82709d2af1c2b2f85827e8
https://doi.org/10.1002/ajmg.b.32048
https://doi.org/10.1002/ajmg.b.32048
Autor:
Scott Stiffler, Bryan Kostelnik, Shirley Y. Hill, Shuhui Wang, Matcheri S. Keshavan, Brian Holmes, Nicholas Zezza, Michael McDermott, Howard Carter
Publikováno v:
Biological Psychiatry. 65:129-136
Background Increased susceptibility for developing alcohol dependence (AD) might be related to structural differences in brain circuits that influence the salience of rewards and / or modify the efficiency of information processing. The role of the o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a9a7b73e812648618d6087270e93726
https://doi.org/10.1016/j.biopsych.2008.09.001
https://doi.org/10.1016/j.biopsych.2008.09.001
Publikováno v:
Journal of Studies on Alcohol and Drugs. 68:625-633
The genes encoding the gamma-aminobutyric acid(A) (GABA(A)) receptor have been the focus of several recent studies investigating the genetic etiology of alcohol dependence. Analyses of multiplex families found a particular gene, GABRA2, to be highly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::193ee6dfa42ce6e5c3fb93042a75b5c5
https://doi.org/10.15288/jsad.2007.68.625
https://doi.org/10.15288/jsad.2007.68.625
Publikováno v:
American Journal of Medical Genetics. :102-113
Alcoholism is currently one of the most serious public health problems in the US. Lifetime prevalence rates are relatively high with one in five men and one in 12 women meeting criteria for this condition. Identification of genetic loci conferring an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11081ed660699fcd203ed125939de3dc
https://doi.org/10.1002/ajmg.b.30013
https://doi.org/10.1002/ajmg.b.30013
Autor:
Michael D. McDermott, Scott Stiffler, Howard Carter, Shuhui Wang, Nicholas Zezza, Shirley Y. Hill
Background: The increased susceptibility for developing alcohol dependence seen in offspring from families with alcohol dependence may be related to structural and functional differences in brain circuits that influence emotional processing. Early ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3acfb8b065f2552e3aa6858ae83ee63
https://europepmc.org/articles/PMC4183218/
https://europepmc.org/articles/PMC4183218/
Autor:
Brian Holmes, Michael McDermott, Scott Stiffler, Nicholas Zezza, Kevin D. Tessner, Shirley Y. Hill, Howard Carter, Shuhui Wang
Offspring from families with multiple cases of alcohol dependence have a greater likelihood of developing alcohol dependence (AD) and related substance use disorders. Greater susceptibility for developing these disorders may be related to structural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7802d487a92c2f5759a9bb5af04e98f2
https://europepmc.org/articles/PMC3293653/
https://europepmc.org/articles/PMC3293653/