Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Nicholas Y. Palermo"'
Autor:
Emma G. Foster, Nicholas Y. Palermo, Yutong Liu, Benson Edagwa, Howard E. Gendelman, Aditya N. Bade
Publikováno v:
Frontiers in Toxicology, Vol 5 (2023)
More than fifteen million women with the human immunodeficiency virus type-1 (HIV-1) infection are of childbearing age world-wide. Due to improved and affordable access to antiretroviral therapy (ART), the number of in utero antiretroviral drug (ARV)
Externí odkaz:
https://doaj.org/article/b9159025b308451580c072153a6e3201
Autor:
Satish Sagar, Ashok Kumar Rathinavel, William E. Lutz, Lucas R. Struble, Surender Khurana, Andy T. Schnaubelt, Nitish Kumar Mishra, Chittibabu Guda, Nicholas Y. Palermo, Mara J. Broadhurst, Tobias Hoffmann, Kenneth W. Bayles, St. Patrick M. Reid, Gloria E. O. Borgstahl, Prakash Radhakrishnan
Publikováno v:
Clinical and Translational Medicine, Vol 11, Iss 2, Pp n/a-n/a (2021)
Externí odkaz:
https://doaj.org/article/1b7d921c47cb43dd8f639abebe3192bb
Autor:
Fadhel A. Alomar, Chengju Tian, Sean R. Bidasee, Zachary L. Venn, Evan Schroder, Nicholas Y. Palermo, Mohammad AlShabeeb, Benson J. Edagwa, Jason J. Payne, Keshore R. Bidasee
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 1; Pages: 274
The incidence of sudden cardiac death (SCD) in people living with HIV infection (PLWH), especially those with inadequate viral suppression, is high and the reasons for this remain incompletely characterized. The timely opening and closing of type 2 r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29947f8e07f1c6a25c6e8df51dffbd72
https://doi.org/10.3390/ijms24010274
https://doi.org/10.3390/ijms24010274
Publikováno v:
The Journal of Physical Chemistry. B
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has evolved into a pandemic of unprecedented scale. This coronavirus enters cells by the interaction of the receptor binding domain (RBD) with the human angiotensin-converting enzyme 2 rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a1057f3ec580444f3f90d7c98fdee57a
https://pubmed.ncbi.nlm.nih.gov/34114829
https://pubmed.ncbi.nlm.nih.gov/34114829
Autor:
Smitha Kizhake, Michel M. Ouellette, Nicholas Y. Palermo, Sandeep Rana, Sarbjit Singh, John Victor Napoleon, Mourad Bendjennat, Vikas Kumar, Amarnath Natarajan, Tom Huxford
Publikováno v:
Chem Commun (Camb)
Inhibitor of nuclear factor kappa-B kinase subunit beta (IKKβ) is a key regulator of the cannonical NF-κB pathway. IKKβ has been validated as a drug target for pathological conditions, which include chronic inflammatory diseases and cancer. Pharma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de52d56a7b8ce1dd678970c240986fb6
https://europepmc.org/articles/PMC8162871/
https://europepmc.org/articles/PMC8162871/
Autor:
Robert A. Davey, Nicholas Y. Palermo, J. J. Patten, Leslie Estrada, Shi Hua Xiang, Colton Thompson, Leah Liu Wang, Manu Anantpadma
Publikováno v:
Antiviral Res
Filoviruses, mainly consisting of Ebola viruses (EBOV) and Marburg viruses (MARV), are enveloped negative-strand RNA viruses which can infect humans to cause severe hemorrhagic fevers and outbreaks with high mortality rates. The filovirus infection i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0161ca0f8ce0cf1dc1b9f8b289cfb1b9
https://europepmc.org/articles/PMC8088776/
https://europepmc.org/articles/PMC8088776/
Autor:
Nicholas Y. Palermo, Gloria E. O. Borgstahl, Ashok Kumar Rathinavel, Andy Schnaubelt, Lucas R. Struble, Satish Sagar, Kenneth W. Bayles, St Patrick Reid, Surender Khurana, Chittibabu Guda, Mara J. Broadhurst, Nitish K. Mishra, William E. Lutz, Prakash Radhakrishnan, Tobias Hoffmann
Publikováno v:
Clinical and Translational Medicine
Clinical and Translational Medicine, Vol 11, Iss 2, Pp n/a-n/a (2021)
Clinical and Translational Medicine, Vol 11, Iss 2, Pp n/a-n/a (2021)
The new coronavirus, SARS-CoV-2, transmits rapidly from human-to-human resulting in the ongoing pandemic. SARS-CoV-2 infects angiotensin-converting enzyme 2 (ACE-2) expressing lung, heart, kidney, intestine, gall bladder, and testicular tissues of pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f58acb225d909a4864d57c84b09ffd46
http://edoc.rki.de/176904/8522
http://edoc.rki.de/176904/8522
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:6081-6084
Nuclear Factor κ B is implicated in tumor progression and chronic inflammatory diseases and is regulated by IκB kinase β (IKKβ). The crystal structure of IKKβ has been recently solved for Xenopus laevis. Homology models of human IKKβ have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c11343612bc63a1231feef70fccfab0
https://doi.org/10.1016/j.bmcl.2011.08.051
https://doi.org/10.1016/j.bmcl.2011.08.051
Autor:
Ziyan Yuan, Smitha Kizhake, Eric A. Kumar, Stephen J. Campbell, Amarnath Natarajan, Nicholas Y. Palermo, J. N. Mark Glover
Publikováno v:
ACS Medicinal Chemistry Letters. 2:764-767
Breast cancer gene 1 carboxy terminus (BRCT) domains are found in a number of proteins that are important for DNA damage response (DDR). The BRCT domains bind phosphorylated proteins, and these protein–protein interactions are essential for DDR and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1c4736d6775748fe1c0500f89b98f84
https://doi.org/10.1021/ml200147a
https://doi.org/10.1021/ml200147a
Autor:
John F. W. Keana, Sándor Lovas, Nicholas Y. Palermo, Tatiana Zaikova, Bo Hyun Kim, Yuri L. Lyubchenko
Publikováno v:
Biochemistry. 50:5154-5162
Misfolding and aggregation of amyloid β-40 (Aβ-40) peptide play key roles in the development of Alzheimer’s disease (AD). However, very little is known about the molecular mechanisms underlying these molecular processes. We developed a novel expe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dbfcb6daf13efe9ffd31bbbfb265c3f7
https://doi.org/10.1021/bi200147a
https://doi.org/10.1021/bi200147a