Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Nicholas W. Kieran"'
Autor:
Moein Yaqubi, Adam M. R. Groh, Marie-France Dorion, Elia Afanasiev, Julia Xiao Xuan Luo, Hadi Hashemi, Sarthak Sinha, Nicholas W. Kieran, Manon Blain, Qiao-Ling Cui, Jeff Biernaskie, Myriam Srour, Roy Dudley, Jeffery A. Hall, Joshua A. Sonnen, Nathalie Arbour, Alexandre Prat, Jo Anne Stratton, Jack Antel, Luke M. Healy
Publikováno v:
Journal of Neuroinflammation, Vol 20, Iss 1, Pp 1-18 (2023)
Abstract Background Microglia are tissue resident macrophages with a wide range of critically important functions in central nervous system development and homeostasis. Method In this study, we aimed to characterize the transcriptional landscape of e
Externí odkaz:
https://doaj.org/article/af75dc06fd684de888eae1e621a52263
Autor:
Nicholas W. Kieran, Rahul Suresh, Marie-France Dorion, Adam MacDonald, Manon Blain, Dingke Wen, Shih-Chieh Fuh, Fari Ryan, Roberto J. Diaz, Jo Anne Stratton, Samuel K. Ludwin, Joshua A. Sonnen, Jack Antel, Luke M. Healy
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-17 (2022)
Abstract Background Astrocytes are the most numerous glial cell type with important roles in maintaining homeostasis and responding to diseases in the brain. Astrocyte function is subject to modulation by microRNAs (miRs), which are short nucleotide
Externí odkaz:
https://doaj.org/article/ff9143aea5044c8bb659c5975e5fd61a
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Neuroinflammation is a prominent pathological feature of all neuroimmunological diseases, including, but not limited to, multiple sclerosis (MS), myasthenia gravis, neuromyelitis optica, and Guillain–Barré syndrome. All currently-approved therapie
Externí odkaz:
https://doaj.org/article/5ef43d3170df4d47903554c464cbf6d5
Publikováno v:
BMJ Leader. :leader-2022
Autor:
Maryam Sharifian-Dorche, Chao You, Hao Li, Dingke Wen, Wu Liu, Mu Yang, Nicholas W. Kieran, Lu Ma, Ruiqi Chen
Publikováno v:
Acta Neurochirurgica. 163:1167-1179
Many blood blister aneurysms (BBAs) have been documented with a rapid progression history in repeated angiography. The underlying mechanism and clinical significance remained elusive. This current study aims to clarify the clinical and histopathologi
Autor:
Dingke Wen, Mu Yang, Lingxiao Huang, Xuyang Liu, Chao You, Hao Li, Xinrui Yang, Nicholas W. Kieran, Lu Ma
Publikováno v:
World Neurosurgery. 138:120-124
Background Intracranial aneurysm (IA) is a debilitating cerebrovascular degeneration. Current clinical diagnosis relies mainly on conventional angiogram except for some peculiar aneurysms. Nonetheless, there is no documentation of aneurysm showing ro
Autor:
Erfan Sharifi, Niusha Khazaei, Nicholas W. Kieran, Sahel Jahangiri Esfahani, Abdulshakour Mohammadnia, Moein Yaqubi
Publikováno v:
Gene. 812
Stem cell differentiation towards various somatic cells and body organs has proven to be an effective technique in the understanding and progression of regenerative medicine. Despite the advances made, concerns regarding the low efficiency of differe
Publikováno v:
Stroke. 51(12)
Autor:
Abdulshakour Mohammadnia, Hadi Hashemi, Sahel Jahangiri Esfahani, Moein Yaqubi, Mohammad Reza Omrani, Erfan Sharifi, Nicholas W. Kieran, Niusha Khazaei
Acquiring a specific transcriptomic signature of the human and mouse cardiomyocyte (CM) will greatly increase our understanding of their biology and associated diseases that remain the most deadly across the world. In this study, using comprehensive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7504d38a1e7e36b3eb2a298687564723
https://doi.org/10.1101/2020.06.14.151399
https://doi.org/10.1101/2020.06.14.151399
Autor:
Zhiyuan Yu, Chao You, Nicholas W. Kieran, Dingke Wen, Xuyang Liu, Lu Ma, Mu Yang, Hao Li, Yue Xiao
Publikováno v:
Acta neurochirurgica. 162(9)
Vasa vasorum is associated with the pathogenesis of various cerebrovascular diseases, but its presence in intracranial aneurysms (IA) and its ability to act as a predicting factor of IA rupture remain unrevealed.Histological investigation was perform