Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Nicholas W. Colangelo"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
In this review, we cover the current understanding of how radiation therapy, which uses ionizing radiation to kill cancer cells, mediates an anti-tumor immune response through the cGAS-STING pathway, and how STING agonists might potentiate this. We e
Externí odkaz:
https://doaj.org/article/41b0141154be4d0d891bc7dcef2d199f
Autor:
Leah M. Katz, Victor Ng, S. Peter Wu, Sherry Yan, David Grew, Samuel Shin, Nicholas W. Colangelo, Allison McCarthy, Harvey I. Pass, Abraham Chachoua, Peter B. Schiff
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
ObjectivesTo investigate the efficacy and safety of lung stereotactic body radiation therapy (SBRT) for non-small cell lung cancer (NSCLC) including oligorecurrent and oligoprogressive disease.MethodsSingle-institution retrospective analysis of 60 NS
Externí odkaz:
https://doaj.org/article/5e041cac3eff420f931de82b88a4f085
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-14 (2020)
Abstract Background Glioblastoma multiforme is an aggressive primary brain tumor that is characterized by local invasive growth and resistance to therapy. The role of the microenvironment in glioblastoma invasiveness remains unclear. While carcinomas
Externí odkaz:
https://doaj.org/article/fa315b6c24d04b5c9b20ed1015fca1ff
Publikováno v:
ASN Neuro, Vol 8 (2016)
Harmful effects that alter the homeostasis of neural stem or progenitor cells (NSPs) can affect regenerative processes in the central nervous system. We investigated the effect of soluble factors secreted by control or 137 Cs-γ-irradiated glioblasto
Externí odkaz:
https://doaj.org/article/a798885defe14d8fbbdcf72854c795a4
Publikováno v:
Canadian Journal of Chemistry. 99:842-849
Large doses of ionizing radiation delivered to tumors at ultra-high dose rates (i.e., in a few milliseconds) paradoxically spare the surrounding healthy tissue while preserving anti-tumor activity (compared with conventional radiotherapy delivered at
Autor:
Nicholas W. Colangelo, Tamjeed Saleh, Sushil Kumar, Canan Kasikara, Hong Li, Bryan T. Ciccarelli, Brendan Smith, Edouard I. Azzam, Stanley G. Kimani, Charalampos G. Kalodimos, Dhriti Mehta, Ke Geng, Viralkumar Davra, Raymond B. Birge
Publikováno v:
Mol Cancer Res
The Crk adaptor protein, a critical modifier of multiple signaling pathways, is overexpressed in many cancers where it contributes to tumor progression and metastasis. Recently, we have shown that Crk interacts with the peptidyl prolyl cis-trans isom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01cc56c08394b840bb80fb7dd6a428b1
https://europepmc.org/articles/PMC8045419/
https://europepmc.org/articles/PMC8045419/
Publikováno v:
Cell Communication and Signaling : CCS
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-14 (2020)
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-14 (2020)
Background Glioblastoma multiforme is an aggressive primary brain tumor that is characterized by local invasive growth and resistance to therapy. The role of the microenvironment in glioblastoma invasiveness remains unclear. While carcinomas release
Autor:
Jintana Meesungnoen, Nicholas W. Colangelo, Edouard I. Azzam, Jean-Paul Jay-Gerin, M.-É. Plourde, Abdullah Muhammad Zakaria
Publikováno v:
Radiat Res
It is well known that molecular oxygen is a product of the radiolysis of water with high-linear energy transfer (LET) radiation, which is distinct from low-LET radiation wherein O(2) radiolytic yield is negligible. Since O(2) is a powerful radiosensi
Autor:
Lisamarie Moore, Sonia M. de Toledo, Shravanthi Chidambaram, Nicholas W. Colangelo, Neha Sharma, Edouard I. Azzam
Publikováno v:
Developmental Neuroscience. 40:312-324
Neural stem cells are attracting enormous attention in regenerative medicine due to their ability to self-renew and differentiate into the cell lineages that constitute the central nervous system. However, little is known about the mechanism underlyi
Publikováno v:
Radiat Res
The goal of radiation therapy is to provide the highest probability of tumor control while minimizing normal tissue toxicity. Recently, it has been discovered that ultra-high dose rates of ionizing radiation may preferentially spare normal tissue ove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cf5089dbd240139362c6b1b09fe6ad2
https://europepmc.org/articles/PMC6949397/
https://europepmc.org/articles/PMC6949397/