Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Nicholas W Lerche"'
Autor:
Mara Jana Broadhurst, Amir Ardeshir, Bittoo Kanwar, Julie Mirpuri, Uma Mahesh Gundra, Jacqueline M Leung, Kirsten E Wiens, Ivan Vujkovic-Cvijin, Charlie C Kim, Felix Yarovinsky, Nicholas W Lerche, Joseph M McCune, P'ng Loke
Publikováno v:
PLoS Pathogens, Vol 8, Iss 11, p e1003000 (2012)
Idiopathic chronic diarrhea (ICD) is a leading cause of morbidity amongst rhesus monkeys kept in captivity. Here, we show that exposure of affected animals to the whipworm Trichuris trichiura led to clinical improvement in fecal consistency, accompan
Externí odkaz:
https://doaj.org/article/0f8380b17577473c9486011ba2e6848e
Autor:
Eunice C Chen, Shigeo Yagi, Kristi R Kelly, Sally P Mendoza, Ross P Tarara, Don R Canfield, Nicole Maninger, Ann Rosenthal, Abigail Spinner, Karen L Bales, David P Schnurr, Nicholas W Lerche, Charles Y Chiu
Publikováno v:
PLoS Pathogens, Vol 7, Iss 7, p e1002155 (2011)
Adenoviruses are DNA viruses that naturally infect many vertebrates, including humans and monkeys, and cause a wide range of clinical illnesses in humans. Infection from individual strains has conventionally been thought to be species-specific. Here
Externí odkaz:
https://doaj.org/article/c8f332a913d64a16953f2aa09afd2d62
Autor:
Nicholas W. Lerche, Sreetharan Kanthaswamy, Hanie A. Elfenbein, Jillian Ng, Amir Ardeshir, Dallas M. Hyde, David Glenn Smith
Publikováno v:
American Journal of Primatology. 76:262-270
Chronic diarrheal disease (CDD) is a critical problem for breeders of captive rhesus macaque (Macaca mulatta), as it results in significant levels of morbidity and death annually. As with other inflammatory disorders, CDD is thought to be caused by e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4996c5142d2fe7073cd7fc77913c764
https://doi.org/10.1002/ajp.22230
https://doi.org/10.1002/ajp.22230
Autor:
Nicholas W. Lerche, Dallas M. Hyde, Frank Ventimiglia, Karen L. Oslund, JoAnn Yee, Amir Ardeshir
Publikováno v:
The Anatomical Record. 296:1169-1179
Idiopathic chronic diarrhea (ICD) is a common cause of morbidity and mortality among juvenile rhesus macaques. While lesions may be absent at colonoscopy, the histopathologic evaluation of the biopsy specimens is consistent with human macroscopic col
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91e8e0ae9cf28c9977953c7166563173
https://doi.org/10.1002/ar.22727
https://doi.org/10.1002/ar.22727
Autor:
David Glenn Smith, Sreetharan Kanthaswamy, Paul Houghton, Jessica Satkoski Trask, Nicholas W. Lerche, Wendy T. Garnica
Publikováno v:
American Journal of Primatology. 75:135-144
Both phenotypic and genetic evidence for asymmetric hybridization between rhesus (Macaca mulatta) and cynomolgus (Macaca fascicularis) macaques has been observed in the region of Indochina where both species are sympatric. The large-scale sharing of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b15ccef95dbc50124a065124eaa5933
https://doi.org/10.1002/ajp.22091
https://doi.org/10.1002/ajp.22091
Publikováno v:
Journal of Virological Methods. 178:143-152
Routine screening for infectious agents is critical in establishing and maintaining specific pathogen free (SPF) nonhuman primate (NHP) colonies. More efficient, higher throughput, less costly reagent, and reduced sample consumption multiplex microbe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6a9bb690c8dc552e97bf2e0604075c8
https://doi.org/10.1016/j.jviromet.2011.09.004
https://doi.org/10.1016/j.jviromet.2011.09.004
Autor:
Nicholas W. Lerche, Paul A. Luciw, David C. Clark, Ching I. Chen, Aaron C. Brault, Patricia A. Pesavento, William K. Reisen
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 83:1249-1258
Since 2004, an East African genotype of Chikungunya virus (CHIKV) has emerged, causing significant epidemics of an arthralgic syndrome. In addition, this virus has been associated for the first time with neonatal transmission and neurological complic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b95333a5844d9f4bb6ce25a91344e9f
https://doi.org/10.4269/ajtmh.2010.10-0290
https://doi.org/10.4269/ajtmh.2010.10-0290
Autor:
Ardythe L. Morrow, Karol Sestak, Tibor Farkas, Nicholas W. Lerche, Edwin Hargitt, Robert W. Cross
Publikováno v:
Journal of Virology. 84:8617-8625
Recently, we reported the discovery and characterization of Tulane virus (TV), a novel rhesus calicivirus (CV) (T. Farkas, K. Sestak, C. Wei, and X. Jiang, J. Virol. 82: 5408-5416, 2008). TV grows well in tissue culture, and it represents a new genus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f01c20599e388b5fa6fc6d40db62f89
https://doi.org/10.1128/jvi.00630-10
https://doi.org/10.1128/jvi.00630-10
Autor:
Nicholas W. Lerche
Publikováno v:
Journal of Immunotoxicology. 7:93-101
Non-human primates have assumed an important role in preclinical safety assessment studies, particularly in the evaluation of biopharmaceutical and immunomodulatory therapies. Naturally occurring simian retrovirus infec- tions may adversely affect th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cc6f33cfe4c3c59fdc0439b0817dd87
https://doi.org/10.3109/15476911003657406
https://doi.org/10.3109/15476911003657406
Autor:
Shannon Flynn, Nicholas W. Lerche, Jessica Satkoski, David Glenn Smith, Sreetharan Kanthaswamy
Publikováno v:
Infection, Genetics and Evolution. 9:769-777
Polymorphisms within the promoter region of the TNF-alpha gene have been associated with altered expression of TNF-alpha and susceptibility to a variety of diseases in humans. Although macaques (Macaca spp.) are frequently used as models to study hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2032e1a31bb2d68d38e1c4f69880a6d1
https://doi.org/10.1016/j.meegid.2009.03.011
https://doi.org/10.1016/j.meegid.2009.03.011