Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Nicholas W Chavkin"'
Autor:
Ana Correia-Branco, Ariel Mei, Sreehari Pillai, Nirmala Jayaraman, Radhika Sharma, Alison G Paquette, Naveen K Neradugomma, Ciara Benson, Nicholas W Chavkin, Qingcheng Mao, Mary C Wallingford
Publikováno v:
Vascular Biology, Vol 5, Iss 1, Pp 1-14 (2023)
The placenta mediates the transport of nutrients, such as inorganic phosphate (Pi), between the maternal and fetal circulatory systems. The placenta itself also requires high levels of nutrient uptake as it develops to provide critical support for fe
Externí odkaz:
https://doaj.org/article/97fa70e62eb8493dabfab01c45b0f293
Autor:
Nicholas W. Chavkin, Soichi Sano, Ying Wang, Kosei Oshima, Hayato Ogawa, Keita Horitani, Miho Sano, Susan MacLauchlan, Anders Nelson, Karishma Setia, Tanvi Vippa, Yosuke Watanabe, Jeffrey J. Saucerman, Karen K. Hirschi, Noyan Gokce, Kenneth Walsh
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 13 (2021)
Background A hallmark of heart failure is cardiac fibrosis, which results from the injury‐induced differentiation response of resident fibroblasts to myofibroblasts that deposit extracellular matrix. During myofibroblast differentiation, fibroblast
Externí odkaz:
https://doaj.org/article/3e860529ade5404993cc7ef1c0e568cb
Autor:
Sampada Chande, Caroline Zeiss, Joëlle Vézier, Nicholas W. Chavkin, Nati Hernando, Cecilia M. Giachelli, Carsten A. Wagner, Laurent Beck, Sarah Beck-Cormier, Clemens Bergwitz
Publikováno v:
Bone Reports, Vol 13, Iss , Pp 100648- (2020)
Externí odkaz:
https://doaj.org/article/f4abdf1d68ec45d6a26fd32eb2dbb6b5
Autor:
Nicholas W. Chavkin, Karen K. Hirschi
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 7 (2020)
The ability to quantify DNA, RNA, and protein variations at the single cell level has revolutionized our understanding of cellular heterogeneity within tissues. Via such analyses, individual cells within populations previously thought to be homogeneo
Externí odkaz:
https://doaj.org/article/9f8ccf085fce4e69af9beb349b227dd2
Publikováno v:
Trends in Cardiovascular Medicine. 32:198-203
Heart failure is prevalent in the elderly population. Inflammatory processes can contribute to the progression of heart failure by altering the balance of tissue healing and pathological remodeling during the injury response. New findings show that a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd523b45b601474db86216fa777e52f6
https://doi.org/10.1016/j.tcm.2021.04.005
https://doi.org/10.1016/j.tcm.2021.04.005
Publikováno v:
Frontiers in Physiology, Vol 9 (2018)
Vascular calcification is the deposition of calcium phosphate minerals in vascular tissue. Vascular calcification occurs by both active and passive processes. Extent and tissue-specific patterns of vascular calcification are predictors of cardiovascu
Externí odkaz:
https://doaj.org/article/eca95ccf392045ed95d1bb522047346e
Autor:
Kyung-Duk Min, Keita Horitani, Ana Filipa Domingues, Soichi Sano, Nicholas W. Chavkin, Emiri Miura-Yura, Ying Wang, Hayato Ogawa, Kenneth Walsh, George Philippos, Miho Sano, Ariel H. Polizio, Katharina Boroviak, Megan A Evans, George S. Vassiliou, Yasufumi Katanasaka, Heather Doviak, Yoshimitsu Yura
Publikováno v:
Circulation Research. 129:684-698
Rationale: Cancer therapy can be associated with short- and long-term cardiac dysfunction. Patients with cancer often exhibit therapy-related clonal hematopoiesis (t-CH), an aggressive form of clonal hematopoiesis that can result from somatic mutatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::237912ea10c1dd19dc8e02656961841e
https://doi.org/10.1161/circresaha.121.319314
https://doi.org/10.1161/circresaha.121.319314
Autor:
Nicholas W. Chavkin, Gael Genet, Mathilde Poulet, Erin D. Jeffery, Corina Marziano, Nafiisha Genet, Hema Vasavada, Elizabeth A. Nelson, Bipul R. Acharya, Anupreet Kour, Jordon Aragon, Stephanie P. McDonnell, Mahalia Huba, Gloria M. Sheynkman, Kenneth Walsh, Karen K. Hirschi
Publikováno v:
Nature Communications. 13
During blood vessel development, endothelial cells become specified toward arterial or venous fates to generate a circulatory network that provides nutrients and oxygen to, and removes metabolic waste from, all tissues. Arterial-venous specification
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0e01eb628f931feb13062c1247129a4
https://doi.org/10.1038/s41467-022-33324-7
https://doi.org/10.1038/s41467-022-33324-7
Autor:
Karen K. Hirschi, Daniel Naveed Tavakol, Jocelyn Chen, Nicholas W. Chavkin, Tara N. Tavakol, Gordana Vunjak-Novakovic
Publikováno v:
Current Stem Cell Reports. 7:174-184
Adult human hematopoiesis resides in the bone marrow (BM), which is comprised of multiple niches capable of supporting hematopoietic stem and progenitor cells (HSPCs), as well as their downstream lineages. In maintaining the blood-forming cells of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c41efd596e3ac396b1fdf01361d6ebd
https://doi.org/10.1007/s40778-021-00195-5
https://doi.org/10.1007/s40778-021-00195-5
Publikováno v:
Circulation Research. 131
Vascular dysfunction and chronic inflammation are characteristics of obesity-induced adipose tissue dysfunction. Proinflammatory cytokines can drive Endothelial-to-Mesenchymal Transition (EndoMT), where endothelial cells transition into mesenchymal-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84ee2f958dc5d6f00d95219dcb481779
https://doi.org/10.1161/res.131.suppl_1.p3128
https://doi.org/10.1161/res.131.suppl_1.p3128