Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Nicholas W, Lerche"'
Autor:
Mara Jana Broadhurst, Amir Ardeshir, Bittoo Kanwar, Julie Mirpuri, Uma Mahesh Gundra, Jacqueline M Leung, Kirsten E Wiens, Ivan Vujkovic-Cvijin, Charlie C Kim, Felix Yarovinsky, Nicholas W Lerche, Joseph M McCune, P'ng Loke
Publikováno v:
PLoS Pathogens, Vol 8, Iss 11, p e1003000 (2012)
Idiopathic chronic diarrhea (ICD) is a leading cause of morbidity amongst rhesus monkeys kept in captivity. Here, we show that exposure of affected animals to the whipworm Trichuris trichiura led to clinical improvement in fecal consistency, accompan
Externí odkaz:
https://doaj.org/article/0f8380b17577473c9486011ba2e6848e
Autor:
Eunice C. Chen, Shigeo Yagi, Kristi R. Kelly, Sally P. Mendoza, Nicole Maninger, Ann Rosenthal, Abigail Spinner, Karen L. Bales, David P. Schnurr, Nicholas W. Lerche, Charles Y. Chiu
Publikováno v:
PLoS Pathogens, Vol 7, Iss 8 (2011)
Externí odkaz:
https://doaj.org/article/7d453000d8ec409cb32236dd169d0284
Autor:
Eunice C Chen, Shigeo Yagi, Kristi R Kelly, Sally P Mendoza, Ross P Tarara, Don R Canfield, Nicole Maninger, Ann Rosenthal, Abigail Spinner, Karen L Bales, David P Schnurr, Nicholas W Lerche, Charles Y Chiu
Publikováno v:
PLoS Pathogens, Vol 7, Iss 7, p e1002155 (2011)
Adenoviruses are DNA viruses that naturally infect many vertebrates, including humans and monkeys, and cause a wide range of clinical illnesses in humans. Infection from individual strains has conventionally been thought to be species-specific. Here
Externí odkaz:
https://doaj.org/article/c8f332a913d64a16953f2aa09afd2d62
Autor:
Nicholas W. Lerche, Sreetharan Kanthaswamy, Hanie A. Elfenbein, Jillian Ng, Amir Ardeshir, Dallas M. Hyde, David Glenn Smith
Publikováno v:
American Journal of Primatology. 76:262-270
Chronic diarrheal disease (CDD) is a critical problem for breeders of captive rhesus macaque (Macaca mulatta), as it results in significant levels of morbidity and death annually. As with other inflammatory disorders, CDD is thought to be caused by e
Autor:
Nicholas W. Lerche, Dallas M. Hyde, Frank Ventimiglia, Karen L. Oslund, JoAnn Yee, Amir Ardeshir
Publikováno v:
The Anatomical Record. 296:1169-1179
Idiopathic chronic diarrhea (ICD) is a common cause of morbidity and mortality among juvenile rhesus macaques. While lesions may be absent at colonoscopy, the histopathologic evaluation of the biopsy specimens is consistent with human macroscopic col
Autor:
David Glenn Smith, Sreetharan Kanthaswamy, Paul Houghton, Jessica Satkoski Trask, Nicholas W. Lerche, Wendy T. Garnica
Publikováno v:
American Journal of Primatology. 75:135-144
Both phenotypic and genetic evidence for asymmetric hybridization between rhesus (Macaca mulatta) and cynomolgus (Macaca fascicularis) macaques has been observed in the region of Indochina where both species are sympatric. The large-scale sharing of
Publikováno v:
Journal of Virological Methods. 178:143-152
Routine screening for infectious agents is critical in establishing and maintaining specific pathogen free (SPF) nonhuman primate (NHP) colonies. More efficient, higher throughput, less costly reagent, and reduced sample consumption multiplex microbe
Autor:
Nicholas W. Lerche, Paul A. Luciw, David C. Clark, Ching I. Chen, Aaron C. Brault, Patricia A. Pesavento, William K. Reisen
Publikováno v:
The American Journal of Tropical Medicine and Hygiene. 83:1249-1258
Since 2004, an East African genotype of Chikungunya virus (CHIKV) has emerged, causing significant epidemics of an arthralgic syndrome. In addition, this virus has been associated for the first time with neonatal transmission and neurological complic
Autor:
Ardythe L. Morrow, Karol Sestak, Tibor Farkas, Nicholas W. Lerche, Edwin Hargitt, Robert W. Cross
Publikováno v:
Journal of Virology. 84:8617-8625
Recently, we reported the discovery and characterization of Tulane virus (TV), a novel rhesus calicivirus (CV) (T. Farkas, K. Sestak, C. Wei, and X. Jiang, J. Virol. 82: 5408-5416, 2008). TV grows well in tissue culture, and it represents a new genus
Autor:
Nicholas W. Lerche
Publikováno v:
Journal of Immunotoxicology. 7:93-101
Non-human primates have assumed an important role in preclinical safety assessment studies, particularly in the evaluation of biopharmaceutical and immunomodulatory therapies. Naturally occurring simian retrovirus infec- tions may adversely affect th