Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nicholas VanDongen"'
Autor:
Abigail Longtine, Ravinandan Venkatasubramanian, Melanie Zigler, Alexandra Lindquist, Sophia Mahoney, Nathan Greenberg, Nicholas VanDongen, Katelyn Ludwig, Kerrie Moreau, Douglas Seals, Zachary Clayton
Publikováno v:
Physiology. 38
The aorta stiffens with aging in both men and women and predicts cardiovascular mortality. Stiffening occurs largely due to aortic wall structural remodeling induced, in part, by chronic low-grade inflammation. Use of animal models in biomedical rese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96f4daa5e309ecc8b09607685cc96ab6
https://doi.org/10.1152/physiol.2023.38.s1.5727898
https://doi.org/10.1152/physiol.2023.38.s1.5727898
Autor:
Ravinandan Venkatasubramanian, Sophia Mahoney, Grace Maurer, Mary Darrah, Katelyn Ludwig, Nicholas VanDongen, Matthew Rossman, Vienna Brunt, Judith Campisi, Douglas Seals, Zachary Clayton
Publikováno v:
Physiology. 38
Doxorubicin (DOXO) chemotherapy induces vascular dysfunction (aortic stiffening and endothelial dysfunction). Cellular senescence and the related increase in oxidative stress, notably mitochondrial reactive oxygen species (mtROS), are implicated in D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9c9c23b245c492b47948bcb507450a3
https://doi.org/10.1152/physiol.2023.38.s1.5733334
https://doi.org/10.1152/physiol.2023.38.s1.5733334
Autor:
Nicholas VanDongen, Sophia Mahoney, Yara Bernaldo de Quirós, Nathan Greenberg, David Hutton, Michael Widlansky, Doulglas Seals, Vienna Brunt, Zachary Clayton
Publikováno v:
Physiology. 38
Aging is the primary risk factor for the development of cardiovascular diseases, largely as a result of reduced arterial function, characterized by endothelial dysfunction and large elastic artery (e.g., aorta) stiffening. Changes in circulating fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ef18e141ad889faed9548ba819bf9c6
https://doi.org/10.1152/physiol.2023.38.s1.5732593
https://doi.org/10.1152/physiol.2023.38.s1.5732593
Autor:
Alexandra Lindquist, Nathan Greenberg, Abigail Longtine, Nicholas VanDongen, Sophia Mahoney, Zachary Clayton, Douglas Seals, Vienna Brunt
Publikováno v:
Physiology. 38
Aging is the main risk factor for cardiovascular diseases (CVD) due in part to stiffening of large elastic arteries (e.g., aorta). High-fiber diets (H-FIB) are associated with reduced risk of CVD, but most people do not meet guidelines for adequate f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80f2bda9e1111e34d82aead8e1cff865
https://doi.org/10.1152/physiol.2023.38.s1.5732615
https://doi.org/10.1152/physiol.2023.38.s1.5732615
Autor:
Nathan Greenberg, Abigail Casso, Alexandra Lindquist, Nicholas VanDongen, Sophia Mahoney, Zachary Clayton, Douglas Seals, Vienna Brunt
Publikováno v:
Physiology. 38
Aging is the primary risk factor for cardiovascular diseases (CVD), the leading cause of death worldwide. Vascular endothelial dysfunction, a key antecedent to CVD, is primarily mediated by excess superoxide-related oxidative stress and decreased nit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::435f1eb6e049d07eed8709f874130227
https://doi.org/10.1152/physiol.2023.38.s1.5726704
https://doi.org/10.1152/physiol.2023.38.s1.5726704
Autor:
Nathan Greenberg, Nicholas VanDongen, Rachel Gioscia-Ryan, Abigail Casso, David Hutton, Zachary Clayton, Douglas Seals, Vienna Brunt
Publikováno v:
Innovation in Aging. 5:823-824
Age-related increases in aortic stiffness contribute to the development of cardiovascular diseases (CVD). To determine whether the gut microbiome (GM) modulates age-related aortic stiffening, we performed fecal microbiota transplants (FMT) between yo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8477cac06e0a24b4255618e33a98e9d9
https://doi.org/10.1093/geroni/igab046.3022
https://doi.org/10.1093/geroni/igab046.3022