Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Nicholas Valmas"'
Autor:
Estella A. Newcombe, Judith Camats-Perna, Mallone L. Silva, Nicholas Valmas, Tee Jong Huat, Rodrigo Medeiros
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-26 (2018)
Abstract Alzheimer’s disease (AD) is a neurodegenerative disorder, most cases of which lack a clear causative event. This has made the disease difficult to characterize and, thus, diagnose. Although some cases are genetically linked, there are many
Externí odkaz:
https://doaj.org/article/d3aef35e156e4fb98b480c016772cf0a
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35037 (2012)
C. elegans is an excellent model system for studying neuroscience using genetics because of its relatively simple nervous system, sequenced genome, and the availability of a large number of transgenic and mutant strains. Recently, microfluidic device
Externí odkaz:
https://doaj.org/article/bc60d07bfaba4a4ab649c4e2b08e43fd
Autor:
Nicholas Valmas, Paul R Ebert
Publikováno v:
PLoS ONE, Vol 1, p e130 (2006)
With the phasing out of ozone-depleting substances in accordance with the United Nations Montreal Protocol, phosphine remains as the only economically viable fumigant for widespread use. However the development of high-level resistance in several pes
Externí odkaz:
https://doaj.org/article/5fd31dbf935441598f989af7cc61a12f
Autor:
Tee Jong Huat, Masashi Kitazawa, Nicholas Valmas, Rodrigo Medeiros, Judith Camats-Perna, Estella A. Newcombe
Publikováno v:
Journal of molecular biology, vol 431, iss 9
As the median age of the population increases, the number of individuals with Alzheimer's disease (AD) and the associated socio-economic burden are predicted to worsen. While aging and inherent genetic predisposition play major roles in the onset of
Autor:
Rodrigo Medeiros, Mallone L. Silva, Estella A. Newcombe, Tee Jong Huat, Nicholas Valmas, Judith Camats-Perna
Publikováno v:
Journal of Neuroinflammation, Vol 15, Iss 1, Pp 1-26 (2018)
Alzheimer’s disease (AD) is a neurodegenerative disorder, most cases of which lack a clear causative event. This has made the disease difficult to characterize and, thus, diagnose. Although some cases are genetically linked, there are many diseases
Publikováno v:
Molecular and cellular neurosciences. 84
Bulk endocytosis allows stimulated neurons to take up a large portion of the presynaptic plasma membrane in order to regenerate synaptic vesicle pools. Actin, one of the most abundant proteins in eukaryotic cells, plays an important role in this proc
Autor:
Andrew G. Tuck, Yosep S. Mau, Anita Goldinger, Nicholas Valmas, Paul R. Ebert, Ramandeep Kaur, Horst Joachim Schirra, Steven Zuryn, Cameron Anderson, Li Ma, Jujiao Kuang, Qiang Cheng, David I. Schlipalius, Rajeswaran Jagadeesan, Patrick J. Collins, Massimo A. Hilliard, Manoj K. Nayak
Publikováno v:
Science. 338:807-810
Dissecting Phosphine Resistance Worldwide populations of pest insects—such as the lesser grain borer, Rhyzopertha dominica , and the rust-red flour beetle, Tribolium castaneum —have become highly resistant to the fumigant phosphine, providing a p
Publikováno v:
Toxicology. 252(1-3)
Phosphine is the most widely used fumigant for the protection of stored commodities against insect pests, especially food products such as grain. However, pest insects are developing resistance to phosphine and thereby threatening its future use. As
Autor:
Bruce D. Hammock, Ubon Cha'on, Paul R. Ebert, Paul E.B. Reilly, Patrick J. Collins, Nicholas Valmas
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 96(1)
The aim of this study is to identify the biochemical mechanism of phosphine toxicity and resistance, using Caenorhabditis elegans as a model organism. To date, the precise mode of phosphine action is unclear. In this report, we demonstrate the follow