Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Nicholas V. Parsonnet"'
Autor:
Zachariah E. Holmes, Desmond J. Hamilton, Taeyoung Hwang, Nicholas V. Parsonnet, John L. Rinn, Deborah S. Wuttke, Robert T. Batey
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Some transcription factors have been proposed to functionally interact with RNA to facilitate proper regulation of gene expression. Here the authors demonstrate that human Sox2 interact directly and with high affinity to RNAs through its HMG DNA-bind
Externí odkaz:
https://doaj.org/article/b2a71949f809466bb1ecf7371b1026f2
Autor:
Deborah S. Wuttke, Robert T. Batey, Taeyoung Hwang, Desmond J. Hamilton, Zachariah E Holmes, Nicholas V. Parsonnet, John L. Rinn
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications
Certain transcription factors are proposed to form functional interactions with RNA to facilitate proper regulation of gene expression. Sox2, a transcription factor critical for maintenance of pluripotency and neurogenesis, has been found associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df0991c0a75e785489c3d69168297bc2
https://doaj.org/article/b2a71949f809466bb1ecf7371b1026f2
https://doaj.org/article/b2a71949f809466bb1ecf7371b1026f2
Autor:
Deborah S. Wuttke, Leslie W. Glustrom, Kenneth Lyon, Victoria Lundblad, Margherita Paschini, Nicholas V. Parsonnet, Cynthia M. Reyes, Tasha B. Toro
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Proteins that bind nucleic acids are frequently categorized as being either specific or nonspecific, with interfaces to match that activity. In this study, we have found that a telomere-binding protein exhibits a degree of specificity fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4023741bf6babe10ce969e9f1aa24aab
http://europepmc.org/articles/PMC6187146
http://europepmc.org/articles/PMC6187146
Autor:
Nickolaus C Lammer, Zachariah E Holmes, Deborah S. Wuttke, Nicholas V. Parsonnet, Robert T. Batey
The glucocorticoid receptor (GR) binds the noncoding RNA Gas5 via its DNA-binding domain (DBD) with functional implications in pro-apoptosis signaling. Here, we report a comprehensive in vitro binding study where we have determined that GR-DBD is a r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9b80be103e2bb287bb1b7c72378d83a
https://europepmc.org/articles/PMC6735959/
https://europepmc.org/articles/PMC6735959/
