Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Nicholas V Metcalf"'
Autor:
Tomer Livne, DoHyun Kim, Nicholas V. Metcalf, Lu Zhang, Lorenzo Pini, Gordon L. Shulman, Maurizio Corbetta
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Spontaneous brain activity, measured with resting state fMRI (R-fMRI), is correlated among regions that are co-activated by behavioral tasks. It is unclear, however, whether spatial patterns of spontaneous activity within a cortical region c
Externí odkaz:
https://doaj.org/article/95122867dc0f470694c552597d68a23e
Autor:
Chiara Favaretto, Michele Allegra, Gustavo Deco, Nicholas V. Metcalf, Joseph C. Griffis, Gordon L. Shulman, Andrea Brovelli, Maurizio Corbetta
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Favaretto et al. show that the brain rapidly alternates between transient connectivity patterns, with cortical regions flexibly synchronizing with two groups of subcortical regions, and that this dynamic is abnormal in stroke patients.
Externí odkaz:
https://doaj.org/article/40eae7e263584185993b60456db0acd4
Autor:
Sebastian Idesis, Chiara Favaretto, Nicholas V. Metcalf, Joseph C. Griffis, Gordon L. Shulman, Maurizio Corbetta, Gustavo Deco
Publikováno v:
NeuroImage: Clinical, Vol 36, Iss , Pp 103233- (2022)
Understanding the effect of focal lesions (stroke) on brain structure-function traditionally relies on behavioral analyses and correlation with neuroimaging data. Here we use structural disconnection maps from individual lesions to derive a causal me
Externí odkaz:
https://doaj.org/article/11b06277c952458cbac556230fc25acb
Publikováno v:
NeuroImage: Clinical, Vol 30, Iss , Pp 102639- (2021)
Lesion studies are an important tool for cognitive neuroscientists and neurologists. However, while brain lesion studies have traditionally aimed to localize neurological symptoms to specific anatomical loci, a growing body of evidence indicates that
Externí odkaz:
https://doaj.org/article/de4d800664c340d6aa436b50ed6e088a
Publikováno v:
NeuroImage, Vol 210, Iss , Pp 116589- (2020)
Focal brain lesions disrupt resting-state functional connectivity, but the underlying structural mechanisms are unclear. Here, we examined the direct and indirect effects of structural disconnections on resting-state functional connectivity in a larg
Externí odkaz:
https://doaj.org/article/5ee267968f824ab9be436c445b6a9e33
Publikováno v:
Cell Reports, Vol 28, Iss 10, Pp 2527-2540.e9 (2019)
Summary: Stroke causes focal brain lesions that disrupt functional connectivity (FC), a measure of activity synchronization, throughout distributed brain networks. It is often assumed that FC disruptions reflect damage to specific cortical regions. H
Externí odkaz:
https://doaj.org/article/65dc7cb4130f46378562be7107455678
Autor:
Manu S. Goyal, Tyler Blazey, Nicholas V. Metcalf, Mark P. McAvoy, Jeremy F. Strain, Maryam Rahmani, Tony J. Durbin, Chengjie Xiong, Tammie L.-S. Benzinger, John C. Morris, Marcus E. Raichle, Andrei G. Vlassenko
Publikováno v:
Proceedings of the National Academy of Sciences. 120
The distribution of brain aerobic glycolysis (AG) in normal young adults correlates spatially with amyloid-beta (Aβ) deposition in individuals with dementia of the Alzheimer type (DAT) and asymptomatic individuals with brain amyloid deposition. Brai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e101d3f5cb3a0fa87643afb6a3957071
https://doi.org/10.1073/pnas.2212256120
https://doi.org/10.1073/pnas.2212256120
Autor:
Leanne Y Lin, Lenny Ramsey, Nicholas V Metcalf, Jennifer Rengachary, Gordon L Shulman, Joshua S Shimony, Maurizio Corbetta
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0202504 (2018)
OBJECTIVES:To examine longitudinal changes in structural and functional connectivity post-stroke in patients with motor impairment, and define their importance for recovery and outcome at 12 months. METHODS:First-time stroke patients (N = 31) were st
Externí odkaz:
https://doaj.org/article/2ed260ac962048bbba4f6776b0528d65
Autor:
Catherine M. Roe, Ganesh M. Babulal, Jamie Hicks, Nicholas V. Metcalf, Beau M. Ances, Jason M. Doherty, Julie K. Wisch, John C. Morris, Ann M. Johnson, Samantha Murphy
Publikováno v:
Scientific Reports. 12
Our objective was to identify functional brain changes that associate with driving behaviors in older adults. Within a cohort of 64 cognitively normal adults (age 60+), we compared naturalistic driving behavior with resting state functional connectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25dc8dc2843afc62cc6d7c38a747590f
https://doi.org/10.1038/s41598-022-09919-x
https://doi.org/10.1038/s41598-022-09919-x
Publikováno v:
NeuroImage : Clinical
NeuroImage: Clinical, Vol 32, Iss, Pp 102812-(2021)
NeuroImage: Clinical, Vol 32, Iss, Pp 102812-(2021)
Highlights • We used covariance-based Granger Causality on resting-state fMRI of stroke patients. • Stroke determines an overall decrease of homotopic Granger causality (GC) • Stroke determines a decrease of GC from and within the lesioned hemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dc22bd8c3b1702bd0b5ee9ee7027fea
http://europepmc.org/articles/PMC8453222
http://europepmc.org/articles/PMC8453222