Zobrazeno 1 - 10
of 355
pro vyhledávání: '"Nicholas V Hud"'
Autor:
Moran Frenkel-Pinter, Marcos Bouza, Facundo M. Fernández, Luke J. Leman, Loren Dean Williams, Nicholas V. Hud, Aikomari Guzman-Martinez
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
One of the early processes enabling the origins of life is thought to be the condensation of building blocks into oligomers and polymers. In this article, the authors report the synthesis of thiodepsipeptides and HS-peptides under mild temperatures a
Externí odkaz:
https://doaj.org/article/df6d52a3f47240ee80e477d8bbe3f713
Autor:
Tyler P. Roche, Pranav J. Nedumpurath, Suneesh C. Karunakaran, Gary B. Schuster, Nicholas V. Hud
Publikováno v:
Life, Vol 13, Iss 11, p 2200 (2023)
Most contemporary theories for the chemical origins of life include the prebiotic synthesis of informational polymers, including strong interpretations of the RNA World hypothesis. Existing challenges to the prebiotic emergence of RNA have encouraged
Externí odkaz:
https://doaj.org/article/c5284636e0084d08af32a84476f634d5
Autor:
Moran Frenkel-Pinter, Jay W. Haynes, Ahmad M. Mohyeldin, Martin C, Alyssa B. Sargon, Anton S. Petrov, Ramanarayanan Krishnamurthy, Nicholas V. Hud, Loren Dean Williams, Luke J. Leman
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Cooperative relationships are widespread among different classes of biopolymers and are predicted to have existed during emergence of life. This study shows that proto-peptides engage in mutually stabilizing interactions with RNA, providing support f
Externí odkaz:
https://doaj.org/article/ce86f8db408449cc807579afb0ac893f
Publikováno v:
ACS Omega, Vol 5, Iss 1, Pp 344-349 (2019)
Externí odkaz:
https://doaj.org/article/669809fe836d49a9a99bb722017f3af3
Autor:
Michael J. Hannon
Publikováno v:
Angewandte Chemie. 121:2674-2674
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9bd92ed1b3a329e8c0c4776bd20a3dbb
https://doi.org/10.1002/ange.200900399
https://doi.org/10.1002/ange.200900399
Autor:
Michael J. Hannon
Publikováno v:
Angewandte Chemie International Edition. 48:2636-2636
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3829201172b8fce5db0e192dd5de834a
https://doi.org/10.1002/anie.200900399
https://doi.org/10.1002/anie.200900399
Autor:
Moran Frenkel-Pinter, Kaitlin C. Jacobson, Jonathan Eskew-Martin, Jay G. Forsythe, Martha A. Grover, Loren Dean Williams, Nicholas V. Hud
Publikováno v:
Life, Vol 12, Iss 2, p 265 (2022)
The origin of biopolymers is a central question in origins of life research. In extant life, proteins are coded linear polymers made of a fixed set of twenty alpha-L-amino acids. It is likely that the prebiotic forerunners of proteins, or protopeptid
Externí odkaz:
https://doaj.org/article/b72948f0feba4f9bbc863250f99e04f8
Autor:
Nicholas V. Hud
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-4 (2018)
The nucleotides of RNA appear to be products of evolution. Experimental studies are showing that plausible proto-nucleotides can be formed in simulated early Earth environments. In turn, these results help to clarify the prebiotic processes that give
Externí odkaz:
https://doaj.org/article/cc3609935234499ba2c45dca17822b32
Publikováno v:
The Journal of Physical Chemistry B. 126:10758-10767
Understanding the interactions and thermodynamic parameters that govern the structure and stability of supramolecular polymers is challenging because of their flexible nature and high sensitivity to weak intermolecular interactions. The application o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac9de3ac1dca014719374bcf53113988
https://doi.org/10.1021/acs.jpcb.2c05934
https://doi.org/10.1021/acs.jpcb.2c05934