Enhanced feedback interventions to promote evidence-based blood transfusion guidance and reduce unnecessary use of blood components: the AFFINITIE research programme including two cluster factorial RCTs

Autor: Robbie Foy, Fabiana Lorencatto, Rebecca Walwyn, Amanda Farrin, Jill Francis, Natalie Gould, Stephen McIntyre, Riya Patel, James Smith, Camilla During, Suzanne Hartley, Robert Cicero, Liz Glidewell, John Grant-Casey, Megan Rowley, Alison Deary, Nicholas Swart, Stephen Morris, Michelle Collinson, Lauren Moreau, Jon Bird, Susan Michie, Jeremy M Grimshaw, Simon J Stanworth

Publikováno v: Programme Grants for Applied Research, Vol 10, Iss 2 (2022)

Background: Blood transfusion is a common but costly treatment. Repeated national audits in the UK suggest that up to one-fifth of transfusions are unnecessary when judged against recommendations for good clinical practice. Audit and feedback seeks t

Externí odkaz: https://doaj.org/article/05f8606470924391be28b62b0e5aabd8

Faecal immunochemical tests versus colonoscopy for post-polypectomy surveillance: an accuracy, acceptability and economic study

Autor: Wendy Atkin, Amanda J Cross, Ines Kralj-Hans, Eilidh MacRae, Carolyn Piggott, Sheena Pearson, Kate Wooldrage, Jeremy Brown, Fiona Lucas, Aaron Prendergast, Natalie Marchevsky, Bhavita Patel, Kevin Pack, Rosemary Howe, Hanna Skrobanski, Robert Kerrison, Nicholas Swart, Julia Snowball, Stephen W Duffy, Stephen Morris, Christian von Wagner, Stephen Halloran

Publikováno v: Health Technology Assessment, Vol 23, Iss 1 (2019)

Background: In the UK, patients with one or two adenomas, of which at least one is ≥ 10 mm in size, or three or four small adenomas, are deemed to be at intermediate risk of colorectal cancer (CRC) and referred for surveillance colonoscopy 3 years

Externí odkaz: https://doaj.org/article/cb3398fda28b4cb3915ca8d980f85aee

Economic evaluation of Cytosponge®-trefoil factor 3 for Barrett esophagus: A cost-utility analysis of randomised controlled trial data

Autor: Stephen Morris, Peter Sasieni, Rebecca C. Fitzgerald, Beth Muldrew, Nicholas Swart, Roberta Maroni

Publikováno v: EClinicalMedicine
EClinicalMedicine, Vol 37, Iss, Pp 100969-(2021)

BackgroundEsophageal adenocarcinoma has a very poor prognosis unless detected early. The Cytosponge-trefoil factor 3 (TFF3) is a non-endoscopic test for Barrett esophagus, a precursor of esophageal adenocarcinoma. Randomised controlled trial data fro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faa5befc83d82647983ed2f76b69f5b6
https://pubmed.ncbi.nlm.nih.gov/34195582

The Age of BLood Evaluation (ABLE) randomised controlled trial: description of the UK-funded arm of the international trial, the UK cost–utility analysis and secondary analyses exploring factors associated with health-related quality of life and health-care costs during the 12-month follow-up

Autor: Helen Campbell, Sue Hemmatapour, David Hope, Timothy S. Walsh, Nicholas Swart, Julia Boyd, Helen Burrows, Elena Pizzo, Stephen Morris, Simon J. Stanworth

Publikováno v: Health Technology Assessment, Vol 21, Iss 62 (2017)
2017, ' The Age of Blood Evaluation randomised controlled trial (ABLE) : Description of the UK funded arm of the international trial, the UK cost-utility analysis, and secondary analyses exploring factors associated with health-related quality of life and healthcare costs during 12 month follow-up ', Health Technology Assessment, vol. 21, no. 62 . https://doi.org/10.3310/hta21620

BackgroundAt present, red blood cells (RBCs) are stored for up to 42 days prior to transfusion. The relative effectiveness and safety of different RBC storage times prior to transfusion is uncertain.ObjectiveTo assess the clinical effectiveness and c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::181feb5cbb39f57d8366b0e5e5dfa6c5
https://doi.org/10.3310/hta21620

Faecal immunochemical tests (FIT) versus colonoscopy for surveillance after screening and polypectomy: a diagnostic accuracy and cost-effectiveness study

Autor: Amanda J, Cross, Kate, Wooldrage, Emma C, Robbins, Ines, Kralj-Hans, Eilidh, MacRae, Carolyn, Piggott, Iain, Stenson, Aaron, Prendergast, Bhavita, Patel, Kevin, Pack, Rosemary, Howe, Nicholas, Swart, Julia, Snowball, Stephen W, Duffy, Stephen, Morris, Christian, von Wagner, Stephen P, Halloran, Wendy S, Atkin

Publikováno v: Gut. 68(9)

The English Bowel Cancer Screening Programme (BCSP) recommends 3 yearly colonoscopy surveillance for patients at intermediate risk of colorectal cancer (CRC) postpolypectomy (those with three to four small adenomas or one ≥10 mm). We investigated w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::28caec52b2e065d15c5f49c795c8808a
https://pubmed.ncbi.nlm.nih.gov/30808647