Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Nicholas Stroustrup"'
Autor:
Francesco A Servello, Rute Fernandes, Matthias Eder, Nathan Harris, Olivier MF Martin, Natasha Oswal, Anders Lindberg, Nohelly Derosiers, Piali Sengupta, Nicholas Stroustrup, Javier Apfeld
Publikováno v:
eLife, Vol 11 (2022)
Hydrogen peroxide is the most common reactive chemical that organisms face on the microbial battlefield. The rate with which hydrogen peroxide damages biomolecules required for life increases with temperature, yet little is known about how organisms
Externí odkaz:
https://doaj.org/article/c41ccb43576f468a9aa853818037f87f
Autor:
Natasha Oswal, Olivier M F Martin, Sofia Stroustrup, Monika Anna Matusiak Bruckner, Nicholas Stroustrup
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 9, p e1010415 (2022)
Aging involves a transition from youthful vigor to geriatric infirmity and death. Individuals who remain vigorous longer tend to live longer, and within isogenic populations of C. elegans the timing of age-associated vigorous movement cessation (VMC)
Externí odkaz:
https://doaj.org/article/b47e7b33825e4d7aaa790ef64b780e15
Autor:
Jodie A Schiffer, Francesco A Servello, William R Heath, Francis Raj Gandhi Amrit, Stephanie V Stumbur, Matthias Eder, Olivier MF Martin, Sean B Johnsen, Julian A Stanley, Hannah Tam, Sarah J Brennan, Natalie G McGowan, Abigail L Vogelaar, Yuyan Xu, William T Serkin, Arjumand Ghazi, Nicholas Stroustrup, Javier Apfeld
Publikováno v:
eLife, Vol 9 (2020)
Hydrogen peroxide is the preeminent chemical weapon that organisms use for combat. Individual cells rely on conserved defenses to prevent and repair peroxide-induced damage, but whether similar defenses might be coordinated across cells in animals re
Externí odkaz:
https://doaj.org/article/2b9224e4540740d888f123584ac93276
Autor:
Xin-Xuan Lin, Ilke Sen, Georges E. Janssens, Xin Zhou, Bryan R. Fonslow, Daniel Edgar, Nicholas Stroustrup, Peter Swoboda, John R. Yates, Gary Ruvkun, Christian G. Riedel
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
The transcription factor DAF-16/FOXO is a downstream effector of insulin/insulin-like growth factor signaling and plays an important role in stress resistance and longevity. Here, the authors show that DAF-16/FOXO can form a complex with HLH-30/TFEB
Externí odkaz:
https://doaj.org/article/560c3b80b1d74b0b81296e799f7bb7fb
Autor:
Georges E. Janssens, Xin-Xuan Lin, Lluís Millan-Ariño, Alan Kavšek, Ilke Sen, Renée I. Seinstra, Nicholas Stroustrup, Ellen A.A. Nollen, Christian G. Riedel
Publikováno v:
Cell Reports, Vol 27, Iss 2, Pp 467-480.e6 (2019)
Summary: Aging strongly influences human morbidity and mortality. Thus, aging-preventive compounds could greatly improve our health and lifespan. Here we screened for such compounds, known as geroprotectors, employing the power of transcriptomics to
Externí odkaz:
https://doaj.org/article/0f0d00ea6e6e44599aab71af29fa6f74
Autor:
Diana Andrea Fernandes de Abreu, Antonio Caballero, Pascal Fardel, Nicholas Stroustrup, Zhunan Chen, Kyunghwa Lee, William D Keyes, Zachary M Nash, Isaac F López-Moyado, Federico Vaggi, Astrid Cornils, Martin Regenass, Anca Neagu, Ivan Ostojic, Chang Liu, Yongmin Cho, Deniz Sifoglu, Yu Shen, Walter Fontana, Hang Lu, Attila Csikasz-Nagy, Coleen T Murphy, Adam Antebi, Eric Blanc, Javier Apfeld, Yun Zhang, Joy Alcedo, Queelim Ch'ng
Publikováno v:
PLoS Genetics, Vol 10, Iss 3, p e1004225 (2014)
Insulin-like peptides (ILPs) play highly conserved roles in development and physiology. Most animal genomes encode multiple ILPs. Here we identify mechanisms for how the forty Caenorhabditis elegans ILPs coordinate diverse processes, including develo
Externí odkaz:
https://doaj.org/article/f2bbc108c2fa40b6adeeb728934d9508
Autor:
Alan A. Cohen, Luigi Ferrucci, Tamàs Fülöp, Dominique Gravel, Nan Hao, Andres Kriete, Morgan E. Levine, Lewis A. Lipsitz, Marcel G. M. Olde Rikkert, Andrew Rutenberg, Nicholas Stroustrup, Ravi Varadhan
Publikováno v:
Nature Aging, 2, 580-591
Nature Aging, 2, 7, pp. 580-591
Nature Aging
Nature Aging, 2, 7, pp. 580-591
Nature Aging
Item does not contain fulltext
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee7c06a0bc91dd4d4bec916b57b0efde
https://hdl.handle.net/2066/291034
https://hdl.handle.net/2066/291034
Autor:
Francesco A Servello, Rute Fernandes, Matthias Eder, Nathan Harris, Olivier MF Martin, Natasha Oswal, Anders Lindberg, Nohelly Derosiers, Piali Sengupta, Nicholas Stroustrup, Javier Apfeld
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::192fca0ae98160b1c0b52e8186c8481a
https://doi.org/10.7554/elife.78941.sa2
https://doi.org/10.7554/elife.78941.sa2
Autor:
Kevin J. Cutler, Carsen Stringer, Teresa W. Lo, Luca Rappez, Nicholas Stroustrup, S. Brook Peterson, Paul A. Wiggins, Joseph D. Mougous
Publikováno v:
Nature Methods
Advances in microscopy hold great promise for allowing quantitative and precise measurement of morphological and molecular phenomena at the single-cell level in bacteria; however, the potential of this approach is ultimately limited by the availabili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f858c24caaafebf2ff1e573bdc0068b9
Autor:
Nicholas Stroustrup
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
instname
Current Opinion in Cell Biology
instname
Current Opinion in Cell Biology
Highlights • Death involves the final collapse of vital physiological networks, and the timing of this collapse provides a systems-level measure of aging. • Many of the best statistical models for lifespan data common in the clinical literature a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4af5c10e461c790b1052905c3d1592a6
https://doi.org/10.1016/j.ceb.2018.07.004
https://doi.org/10.1016/j.ceb.2018.07.004