Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Nicholas Seneca"'
Autor:
Marie‐Emmanuelle Riviere, Raymond Scott Turner, Yihan Sui, Nathalie Laurent, Jessica B. Langbaum, Pilar Cazorla, Javier Ricart, Nicholas Seneca, Angelika Caputo, Eric M. Reiman, Pierre N. Tariot, Ana Graf
Publikováno v:
Alzheimer's & Dementia. 17
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c102594b0179d86891a789fd9e1ff2a5
https://doi.org/10.1002/alz.051287
https://doi.org/10.1002/alz.051287
Autor:
Vissia Viglietta, Fonda Liu, Marie-Laure Rouzade-Dominguez, Marie-Emmanuelle Riviere, Yihan Sui, Udo Eichenlaub, Eric M. Reiman, Yuchen Chien, Ulf Neumann, Beth Borowsky, Matt Quinn, Nicholas Seneca, Ana Graf, Pilar Cazorla, Angelika Caputo
Publikováno v:
Alzheimer's & Dementia. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02208c30f5767572fdf686900de1e5f2
https://doi.org/10.1002/alz.041143
https://doi.org/10.1002/alz.041143
Autor:
Robert A. Comley, Sandra Sanabria, David Alagille, Edilio Borroni, Caroline Papin, Gilles Tamagnan, John Seibyl, Ken Marek, Olivier Barret, Mark A. Mintun, Thomas J. Morley, Nicholas Seneca, Robby M. Weimer, Danna Jennings
Publikováno v:
Journal of Nuclear Medicine. 58:1124-1131
18F-AV-1451 is currently the most widely used of several experimental tau PET tracers. The objective of this study was to evaluate 18F-AV-1451 binding with full kinetic analysis using a metabolite-corrected arterial input function and to compare para
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b4f1117186361b816c5a3724f0fa7d29
https://doi.org/10.2967/jnumed.116.182881
https://doi.org/10.2967/jnumed.116.182881
Autor:
Ming-Kai Chen, Yiyun Huang, Anne Chastre, Beata Planeta, Eunkyung Park, Daniel Pelletier, Jae-Yun Lee, Keunpoong Lim, Nicholas Seneca, Shu-fei Lin, David Leppert, Jean-Dominique Gallezot, Kevin C. O’Connor, Shuang Liu, Aracely Delgadillo, Richard E. Carson
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 42:1081-1092
Activated microglia play a key role in inflammatory demyelinating injury in multiple sclerosis (MS). Microglial activation can be measured in vivo using a positron emission tomography (PET) ligand 11C-PBR28. We evaluated the test-retest variability (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a381ffb0949c18f6cca8a7158d933f8
https://doi.org/10.1007/s00259-015-3043-4
https://doi.org/10.1007/s00259-015-3043-4
Autor:
Sandra J. Campbell, Nicola R. Sibson, Matthew Tredwell, Nicholas Seneca, Yvonne Couch, Alex M. Dickens, Edward A. Warren, Daniel C. Anthony, David Leppert, Veerle Kersemans, Begona Checa, Véronique Gouverneur
Publikováno v:
Annals of Clinical and Translational Neurology
OBJECTIVE: The mechanism of action of anti-B cell therapy in multiple sclerosis (MS) is not fully understood. Here, we compared the effect of anti-CD20 therapy on microglial activation in two distinct focal rat models of MS. METHODS: The effect of an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f972e73ea4de88dc5c272624536f3289
https://doi.org/10.1002/acn3.94
https://doi.org/10.1002/acn3.94
Autor:
Olivier, Barret, David, Alagille, Sandra, Sanabria, Robert A, Comley, Robby M, Weimer, Edilio, Borroni, Mark, Mintun, Nicholas, Seneca, Caroline, Papin, Thomas, Morley, Ken, Marek, John P, Seibyl, Gilles D, Tamagnan, Danna, Jennings
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 58(7)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e52a1ed416996cef33d80eeee500e565
https://pubmed.ncbi.nlm.nih.gov/27908967
https://pubmed.ncbi.nlm.nih.gov/27908967
Autor:
Riitta Parkkola, Marko Seppänen, Sannamari Hautaniemi, Timo Möttönen, Pirjo Nuutila, Anne Roivainen, Timo Yli-Kerttula, Luminita Pricop, Nicholas Seneca, Rudyard Ress, Vesa Oikonen
Publikováno v:
European Journal of Nuclear Medicine and Molecular Imaging. 40:403-410
This study evaluated the potential of functional imaging to monitor disease activity and response to treatment with disease-modifying antirheumatic drugs (DMARD) in DMARD-naive patients with early rheumatoid arthritis (RA). The study involved 17 pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3057a6a7f574959424c8b490f6f3c304
https://doi.org/10.1007/s00259-012-2282-x
https://doi.org/10.1007/s00259-012-2282-x
Autor:
Jeih-San Liow, William C. Kreisl, Robert B. Innis, Victor W. Pike, Nicholas Seneca, Peter Herscovitch, Cheryl L. Morse, Nobuyo Kimura, Sami S. Zoghbi
Publikováno v:
Journal of Nuclear Medicine. 51:559-566
Permeability-glycoprotein (P-gp), an efflux transporter in several organs, acts at the blood-brain barrier to protect the brain from exogenous toxins. P-gp almost completely blocks brain entry of the PET radiotracer (11)C-N-desmethyl-loperamide ((11)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d23e425671f32e18779a83696c4d5a9
https://doi.org/10.2967/jnumed.109.070151
https://doi.org/10.2967/jnumed.109.070151
Autor:
Kimberly Jenko, William C. Kreisl, Jeih-San Liow, Peter Herscovitch, Robert B. Innis, Andrew Taku, Victor W. Pike, Nicholas Seneca, Sami S. Zoghbi, Robert L. Gladding
Publikováno v:
Journal of Nuclear Medicine. 50:807-813
P-glycoprotein (P-gp) is a membrane-bound efflux pump that limits the distribution of drugs to several organs of the body. At the blood-brain barrier, P-gp blocks the entry of both loperamide and its metabolite, N-desmethyl-loperamide (N-dLop), and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fae642f4bcad97117b3e3bc5dd2893fe
https://doi.org/10.2967/jnumed.108.058453
https://doi.org/10.2967/jnumed.108.058453
Autor:
Robert B. Innis, Nicholas Seneca, Lisheng Cai, Jinsoo Hong, Victor W. Pike, Jeih San Liow, John T. Little, Paul S. Aisen, Robert L. Gladding, Sami S. Zoghbi
Publikováno v:
Current Radiopharmaceuticalse. 2:129-136
Alzheimers disease (AD) is characterized pathologically by the accumulation of β-amyloid plaques in brain. We developed a novel positron emission tomographic (PET) radioligand, [11C]MeS-IMPY ([S-methyl-11C]N,N-dimethyl- 4-(6-(methylthio)imidazo[1,2-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20c6830341b821c8d05bb84ea2509f2d
https://doi.org/10.2174/1874471010902020129
https://doi.org/10.2174/1874471010902020129