Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Nicholas Rooney"'
Autor:
Karen Blyth, Ewan R. Cameron, Joanne Edwards, Owen J. Sansom, Joshua D.G. Leach, William Clark, Colin Nixon, Dimitris Athineos, Steven Howard, Ann Hedley, Kirsteen J. Campbell, J. Henry M. Däbritz, Laura McDonald, Susan M. Mason, Nicholas Rooney
All Supplementary data figures and legends. Supplementary Figure 1. In Silico analysis of RUNX1 expression in human kidney cancer. Supplementary Figure 2. Knockdown of RUNX1 with shRNA causes a growth defect in two ccRCC cell lines. Supplementary Fig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f1cd5d76d642f2d71107273237d8e57
https://doi.org/10.1158/0008-5472.22423628
https://doi.org/10.1158/0008-5472.22423628
Autor:
Karen Blyth, Ewan R. Cameron, Joanne Edwards, Owen J. Sansom, Joshua D.G. Leach, William Clark, Colin Nixon, Dimitris Athineos, Steven Howard, Ann Hedley, Kirsteen J. Campbell, J. Henry M. Däbritz, Laura McDonald, Susan M. Mason, Nicholas Rooney
RNAseq data set
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af3afad67572d436fb44e2aeb5dd5d2
https://doi.org/10.1158/0008-5472.22423634.v1
https://doi.org/10.1158/0008-5472.22423634.v1
Autor:
Karen Blyth, Ewan R. Cameron, Joanne Edwards, Owen J. Sansom, Joshua D.G. Leach, William Clark, Colin Nixon, Dimitris Athineos, Steven Howard, Ann Hedley, Kirsteen J. Campbell, J. Henry M. Däbritz, Laura McDonald, Susan M. Mason, Nicholas Rooney
The recurring association of specific genetic lesions with particular types of cancer is a fascinating and largely unexplained area of cancer biology. This is particularly true of clear cell renal cell carcinoma (ccRCC) where, although key mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e9b2c8fc44285f92b9bb2df21b6d2ad
https://doi.org/10.1158/0008-5472.c.6511538.v1
https://doi.org/10.1158/0008-5472.c.6511538.v1
Autor:
Karen Blyth, Ewan R. Cameron, Joanne Edwards, Owen J. Sansom, Joshua D.G. Leach, William Clark, Colin Nixon, Dimitris Athineos, Steven Howard, Ann Hedley, Kirsteen J. Campbell, J. Henry M. Däbritz, Laura McDonald, Susan M. Mason, Nicholas Rooney
Supplementary Table 1. The relationship between RUNX2 and clinico-pathological characteristics of kidney cancer in the TMA study.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ccc08d2bbed38aad46b42df51d9ec63
https://doi.org/10.1158/0008-5472.22423625
https://doi.org/10.1158/0008-5472.22423625
Autor:
William C. Clark, J. Henry M. Däbritz, Joshua D.G. Leach, Joanne Edwards, Laura McDonald, Colin Nixon, Owen J. Sansom, Steven P. Howard, Karen Blyth, Susan M. Mason, Dimitris Athineos, Ewan R. Cameron, Kirsteen J. Campbell, Nicholas Rooney, Ann Hedley
The recurring association of specific genetic lesions with particular types of cancer is a fascinating and largely unexplained area of cancer biology. This is particularly true of clear cell renal cell carcinoma (ccRCC) where, although key mutations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::169d296a122917def6d98522847289d1
https://eprints.gla.ac.uk/212726/1/212726.pdf
https://eprints.gla.ac.uk/212726/1/212726.pdf
Autor:
Nicholas Rooney, Daniel Mendoza-Villanueva, Paul Shore, Ewan R. Cameron, Karen Blyth, Alessandra I. Riggio
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9789811032318
A full understanding of RUNX gene function in different epithelial lineages has been thwarted by the lethal phenotypes observed when constitutively knocking out these mammalian genes. However temporal expression of the Runx genes throughout the diffe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ed68bb9050a48120b4da87e94576c76
https://doi.org/10.1007/978-981-10-3233-2_22
https://doi.org/10.1007/978-981-10-3233-2_22
Autor:
Charles H. Streuli, Nicholas Rooney
Publikováno v:
Rooney, N & Streuli, C H 2011, ' How integrins control mammary epithelial differentiation: A possible role for the ILK-PINCH-Parvin complex ', FEBS Letters, vol. 585, no. 11, pp. 1663-1672 . https://doi.org/10.1016/j.febslet.2011.05.014
Differentiation into tissue-specific cell types occurs in response to numerous external signals. Integrins impart signals from the extracellular matrix microenvironment that are required for cell differentiation. However, the precise cytoplasmic tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb8193ca7c85fe22b66d492243a07caa
https://doi.org/10.1016/j.febslet.2011.05.014
https://doi.org/10.1016/j.febslet.2011.05.014
Autor:
Richard M. Monaghan, Alan J. Whitmarsh, Tereza Andreou, Gino B. Poulin, Robert G. Barnes, Kate Fisher, Nicholas Rooney
Publikováno v:
Nature cell biology
Monaghan, R M, Barnes, R G, Fisher, K, Andreou, T, Rooney, N, Poulin, G B & Whitmarsh, A J 2015, ' A nuclear role for the respiratory enzyme CLK-1 in regulating mitochondrial stress responses and longevity ', Nature Cell Biology, vol. 17, no. 6, pp. 782-792 . https://doi.org/10.1038/ncb3170
Monaghan, R M, Barnes, R G, Fisher, K, Andreou, T, Rooney, N, Poulin, G B & Whitmarsh, A J 2015, ' A nuclear role for the respiratory enzyme CLK-1 in regulating mitochondrial stress responses and longevity ', Nature Cell Biology, vol. 17, no. 6, pp. 782-792 . https://doi.org/10.1038/ncb3170
The coordinated regulation of mitochondrial and nuclear activities is essential for cellular respiration and its disruption leads to mitochondrial dysfunction, a hallmark of ageing. Mitochondria communicate with nuclei through retrograde signalling p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e1d03bc836a82a943f4d205827c27fb
https://pubmed.ncbi.nlm.nih.gov/25961505
https://pubmed.ncbi.nlm.nih.gov/25961505
Autor:
Nicholas Rooney, Duncan A.F. Robertson, Karen L. Wright, Stephen G. Ward, Jeremy Tate, Mark Feeney, Melanie J. Welham
Publikováno v:
Gastroenterology. 129:437-453
Background & Aims: Two G-protein—coupled cannabinoid receptors, termed CB1 and CB2 , have been identified and several mammalian enteric nervous systems express CB1 receptors and produce endocannabinoids. An immunomodulatory role for the endocannabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6577b73ed73c7bfe36200c8c84689d77
https://doi.org/10.1016/j.gastro.2005.05.026
https://doi.org/10.1016/j.gastro.2005.05.026
Publikováno v:
Lancet (London, England). 383(9936)
A 39-year-old man presented to his general practitioner in February, 2013, with a 6 month history of drenching night sweats and 10 kg unintentional weight loss in the previous 2 months. He had no gastrointestinal symptoms, was a non-smoker with minim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be893c6e93a5a78d301f60060a6242ca
https://pubmed.ncbi.nlm.nih.gov/25263674
https://pubmed.ncbi.nlm.nih.gov/25263674