Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Nicholas R. Weir"'
Autor:
David W Morgens, Charlene Chan, Andrew J Kane, Nicholas R Weir, Amy Li, Michael M Dubreuil, C Kimberly Tsui, Gaelen T Hess, Adam Lavertu, Kyuho Han, Nicole Polyakov, Jing Zhou, Emma L Handy, Philip Alabi, Amanda Dombroski, David Yao, Russ B Altman, Jason K Sello, Vladimir Denic, Michael C Bassik
Publikováno v:
eLife, Vol 8 (2019)
The small molecule Retro-2 prevents ricin toxicity through a poorly-defined mechanism of action (MOA), which involves halting retrograde vesicle transport to the endoplasmic reticulum (ER). CRISPRi genetic interaction analysis revealed Retro-2 activi
Externí odkaz:
https://doaj.org/article/f8b0b64eb9da49ff8b1b2ae4b6712fa1
Autor:
Christopher J Shoemaker, Tina Q Huang, Nicholas R Weir, Nicole J Polyakov, Sebastian W Schultz, Vladimir Denic
Publikováno v:
PLoS Biology, Vol 17, Iss 4, p e2007044 (2019)
The power of forward genetics in yeast is the foundation on which the field of autophagy research firmly stands. Complementary work on autophagy in higher eukaryotes has revealed both the deep conservation of this process, as well as novel mechanisms
Externí odkaz:
https://doaj.org/article/d998a4d04a914e249a28a3291129a9bf
Publikováno v:
eLife, Vol 6 (2017)
Msp1 is a conserved AAA ATPase in budding yeast localized to mitochondria where it prevents accumulation of mistargeted tail-anchored (TA) proteins, including the peroxisomal TA protein Pex15. Msp1 also resides on peroxisomes but it remains unknown h
Externí odkaz:
https://doaj.org/article/423c5120da494857b5884657a9ad6529
Publikováno v:
Review of Scientific Instruments. 93:043005
A field programmable gate array (FPGA)-based timing and trigger control system has been developed for the Dynamic Compression Sector (DCS) user facility located at the Advanced Photon Source (APS) at Argonne National Laboratory. The DCS is a first-of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07a34c4585eecfee51e060de6fbe8d26
https://doi.org/10.1063/5.0081205
https://doi.org/10.1063/5.0081205
Autor:
Fabio Pacifici, Nicholas R. Weir, Jason Brown, Scott Soenen, Adam Van Etten, Ronny Hänsch, Todd M. Bacastow, Daniel Hogan, Alexei Bastidas, Ryan Lewis, Jacob Shermeyer
Publikováno v:
CVPR Workshops
Within the remote sensing domain, a diverse set of acquisition modalities exist, each with their own unique strengths and weaknesses. Yet, most of the current literature and open datasets only deal with electro-optical (optical) data for different de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::516305b355b9f55dde50da85e3008524
Publikováno v:
IGARSS
Identification of road networks and optimal routes directly from remote sensing is of critical importance to a broad array of humanitarian and commercial applications. Yet while identification of road pixels has been attempted before, estimation of r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb42dde7102008c33ce7d391730ef6b0
Autor:
Adam Lavertu, Nicholas R. Weir, Amanda Dombroski, Amy Li, Nicole J. Polyakov, David Yao, Vladimir Denic, Jing Zhou, Charlene Chan, Gaelen T. Hess, David W. Morgens, Kyuho Han, Andrew J Kane, Jason K. Sello, C. Kimberly Tsui, Michael M. Dubreuil, Russ B. Altman, Philip Alabi, Emma L. Handy, Michael C. Bassik
Publikováno v:
eLife, Vol 8 (2019)
eLife
eLife
The small molecule Retro-2 prevents ricin toxicity through a poorly-defined mechanism of action (MOA), which involves halting retrograde vesicle transport to the endoplasmic reticulum (ER). CRISPRi genetic interaction analysis revealed Retro-2 activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b82cafeb61e78e78bd0b38dc89ac72c6
https://doi.org/10.7554/elife.48434
https://doi.org/10.7554/elife.48434
Autor:
Charlene Chan, Andrew J Kane, David W. Morgens, C. Kimberly Tsui, Amanda Dombroski, Amy Li, Nicholas R. Weir, Gaelen T. Hess, Russ B. Altman, Vladimir Denic, Jing Zhou, Emma L. Handy, Adam Lavertu, Jason K. Sello, Kyuho Han, Michael C. Bassik, Philip Alabi, Michael M. Dubreuil, David Yao, Nicole J. Polyakov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdab76f48078f5cb90043821815d13a1
https://doi.org/10.7554/elife.48434.022
https://doi.org/10.7554/elife.48434.022
Autor:
Varun Kumar, Jacob Shermeyer, Alexei Bastidas, Adam Van Etten, Sean McPherson, David Lindenbaum, Hanlin Tang, Nicholas R. Weir
Publikováno v:
ICCV
Detection and segmentation of objects in overheard imagery is a challenging task. The variable density, random orientation, small size, and instance-to-instance heterogeneity of objects in overhead imagery calls for approaches distinct from existing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3197f3b65e2c6eae7dddb06a00d5dcc0
https://doi.org/10.1109/iccv.2019.00108
https://doi.org/10.1109/iccv.2019.00108
SummarySelective autophagy comprises cytoplasm-to-lysosome trafficking routes that transport cargos using double-membrane vesicles (autophagosomes). Cargos are detected by receptor proteins, which typically also bind to lipid-conjugated LC3 proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdd8104114984c4f28f4808449bf7991