Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Nicholas R. StC. Sinclair"'
Autor:
Nicholas R. StC. Sinclair
Publikováno v:
Scandinavian journal of immunologyREFERENCES. 94(5)
Costimulatory and coinhibitory mechanisms appear to be involved throughout immune responses to control their specificity and level. Many mechanisms operate; therefore, various theoretical models should be considered complementary rather than competin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6c30a30f4aacdc625b2c2abb4007161
https://pubmed.ncbi.nlm.nih.gov/34940993
https://pubmed.ncbi.nlm.nih.gov/34940993
Autor:
Joseph V. Pergolizzi, Swati Nagar, Errol M. Gould, Robert Taylor, Sumedha A. Labhsetwar, Nicholas R. StC. Sinclair, Robert B. Raffa
Publikováno v:
Journal of Opioid Management. 8:383-393
Objective: The aging population generally has greater need for analgesics and is best served by having as many good therapeutic options as possible. Geriatric analgesia requires special consideration of age-associated physiologic changes that can aff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb1bc3bf93e5182273cff48fd7f50943
https://doi.org/10.5055/jom.2012.0138
https://doi.org/10.5055/jom.2012.0138
Autor:
Chris Gharibo, Nicholas R. StC. Sinclair, Robert W. Taylor, Marco Pappagallo, Tong J. Gan, Charles Fleischer, Aaron Tabor, Robert B. Raffa
Publikováno v:
Pain Practice. 12:610-619
Background: Topical analgesics are important products in the armamentarium for pain relief. Methods and Findings: This study compared a topical analgesic product containing menthol to the same product with the addition of oxygenated glycerol triester
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bb1c669d5549206a273fd04c230470d
https://doi.org/10.1111/j.1533-2500.2012.00529.x
https://doi.org/10.1111/j.1533-2500.2012.00529.x
Publikováno v:
Bone and Joint Institute
B cells are stimulated by antigens or by polyclonal activators such as bacterial lipopolysaccharide (LPS) to produce antibody. In nonautoimmune strains of mice, LPS-stimulated antibody responses are inhibited by crosslinking the B cell antigen-recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8a7f389864da29a56a4adb3eca4e3e3
https://doi.org/10.1006/cimm.1995.1153
https://doi.org/10.1006/cimm.1995.1153
Autor:
Nicholas R. StC. Sinclair
Publikováno v:
Immunology and Cell Biology. 73:169-173
Observations on many antigen-receptor transgenic models with anti-self specificities have been interpreted as proof for clonal deletion or for mechanisms involved in clonal deletion. At the same time, there is increasing evidence that many lymphocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d5f651ab6e708e431da9b140c46b5a6
https://doi.org/10.1038/icb.1995.27
https://doi.org/10.1038/icb.1995.27
Publikováno v:
Immunologic Research. 13:10-20
Ligation of surface immunoglobulin on resting or activated nonautoimmune B cells inhibited lipopolysaccharide (LPS)-induced total IgM production. B cells from NZB, (NZB x NZW)F1, and BXSB mice were relatively resistant, but B cells from NZW or MRL/lp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::756a518cafe3e360d223230dd8100940
https://doi.org/10.1007/bf02918220
https://doi.org/10.1007/bf02918220
Publikováno v:
Immunologic Research. 12:349-357
Continuous blockade of B-cell antigen receptors (BCRs) with Fab alpha sIg prevents the anti-ssDNA response of high, but not low, density B cells. Signaling via the BCRs, by prior exposure to crosslinking F(ab')2 alpha sIg, had no effect on the sponta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b078742993f81a192a2f84dad6897079
https://doi.org/10.1007/bf02935508
https://doi.org/10.1007/bf02935508
Publikováno v:
Autoimmunity. 11:281-287
Anti-DNA antibodies occur in outwardly normal individuals as well as in various forms of autoimmune disease. A number of publications have reported on the ability of added DNA to either induce or inhibit the in vitro production of anti-DNA antibody.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfd801c1597009c83366fb7dc93c71da
https://doi.org/10.3109/08916939209035166
https://doi.org/10.3109/08916939209035166
Autor:
Nicholas R. StC. Sinclair
Publikováno v:
Cellular Immunology. 130:204-212
The many signals that control the progress of various immune responses to both foreign and self antigens can be divided into no less than three major groups. The first group is the initial positive stimulus, associated with activation events through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3edd532becfdbf3efcc6d5426dc7dfa
https://doi.org/10.1016/0008-8749(90)90174-p
https://doi.org/10.1016/0008-8749(90)90174-p
Autor:
Nicholas R. StC. Sinclair
Publikováno v:
Autoimmunity. 6:131-142
Two regulatory mechanisms, based on the contrasting concepts of imprinting (clonal theories and idiotypic networks) and of ongoing regulation of immune responses (by antigen and end products with specificity for antigen), give rise to different predi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0b006350666d0b05948a9fec3abc018
https://doi.org/10.3109/08916939008993377
https://doi.org/10.3109/08916939008993377