Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Nicholas R Hum"'
Autor:
Naiomy D Rios‐Arce, Deepa K Murugesh, Nicholas R Hum, Aimy Sebastian, Elias H Jbeily, Blaine A Christiansen, Gabriela G Loots
Publikováno v:
JBMR Plus, Vol 6, Iss 5, Pp n/a-n/a (2022)
ABSTRACT Type 1 diabetes mellitus (T1DM) affects 9.5% of the population. T1DM is characterized by severe insulin deficiency that causes hyperglycemia and leads to several systemic effects. T1DM has been suggested as a risk factor for articular cartil
Externí odkaz:
https://doaj.org/article/c3e2d3a89854486ebd278c4d6385c2e3
Autor:
Nicholas R Hum, Feliza A Bourguet, Aimy Sebastian, Doris Lam, Ashlee M Phillips, Kristina R Sanchez, Amy Rasley, Gabriela G Loots, Dina R Weilhammer
Publikováno v:
PLoS Pathogens, Vol 18, Iss 5, p e1010231 (2022)
Rift Valley fever virus (RVFV) is a highly pathogenic mosquito-borne virus capable of causing hepatitis, encephalitis, blindness, hemorrhagic syndrome, and death in humans and livestock. Upon aerosol infection with RVFV, the brain is a major site of
Externí odkaz:
https://doaj.org/article/81cf85fca71d44c78decf6e001ebfc84
Autor:
Aimy Sebastian, Nicholas R Hum, Deepa K Murugesh, Sarah Hatsell, Aris N Economides, Gabriela G Loots
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188264 (2017)
Wnt3a is a major regulator of bone metabolism however, very few of its target genes are known in bone. Wnt3a preferentially signals through transmembrane receptors Frizzled and co-receptors Lrp5/6 to activate the canonical signaling pathway. Previous
Externí odkaz:
https://doaj.org/article/9000d5555a634089a26538a19c162fd9
Autor:
Chandrakumar Bogguri, Vivek Kurien George, Beheshta Amiri, Alexander Ladd, Nicholas R. Hum, Aimy Sebastian, Heather A. Enright, Carlos A. Valdez, T. Nathan Mundhenk, Jose Cadena, Doris Lam
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Organophosphorus nerve agents (OPNA) are hazardous environmental exposures to the civilian population and have been historically weaponized as chemical warfare agents (CWA). OPNA exposure can lead to several neurological, sensory, and motor symptoms
Externí odkaz:
https://doaj.org/article/2c2b58c2460a469e8a5d95815e53ca1f
Autor:
Bryan D Hudson, Nicholas R Hum, Cynthia B Thomas, Ayano Kohlgruber, Aimy Sebastian, Nicole M Collette, Matthew A Coleman, Blaine A Christiansen, Gabriela G Loots
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142058 (2015)
Inhibitors of Wnt signaling have been shown to be involved in prostate cancer (PC) metastasis; however the role of Sclerostin (Sost) has not yet been explored. Here we show that elevated Wnt signaling derived from Sost deficient osteoblasts promotes
Externí odkaz:
https://doaj.org/article/3f93e403e6164dc4a2e22250d5ef1993
Autor:
Susana Tejeda-Garibay, Lihong Zhao, Nicholas R. Hum, Maria Pimentel, Anh L. Diep, Beheshta Amiri, Suzanne S. Sindi, Dina R. Weilhammer, Gabriela G. Loots, Katrina K. Hoyer
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 7 (2024)
ABSTRACT Coccidioidomycosis, also known as Valley fever, is a disease caused by the fungal pathogen Coccidioides. Unfortunately, patients are often misdiagnosed with bacterial pneumonia, leading to inappropriate antibiotic treatment. The soil Bacillu
Externí odkaz:
https://doaj.org/article/cd7d8d3c7c3c492f8b562e20e318645b
Autor:
Gabriela G Loots, Anne Bergmann, Nicholas R Hum, Catherine E Oldenburg, Andrea E Wills, Na Hu, Ivan Ovcharenko, Richard M Harland
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68548 (2013)
Identifying gene regulatory elements and their target genes in vertebrates remains a significant challenge. It is now recognized that transcriptional regulatory sequences are critical in orchestrating dynamic controls of tissue-specific gene expressi
Externí odkaz:
https://doaj.org/article/8831f8f26c7e4261b3c006eed7b12ee6
Autor:
Dorothy J. You, Bria M. Gorman, Noah Goshi, Nicholas R. Hum, Aimy Sebastian, Yong Ho Kim, Heather A. Enright, Bruce A. Buchholz
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10288 (2024)
The frequency, duration, and size of wildfires have been increasing, and the inhalation of wildfire smoke particles poses a significant risk to human health. Epidemiological studies have shown that wildfire smoke exposure is positively associated wit
Externí odkaz:
https://doaj.org/article/2f952f24a56e4d25adec97b0b3e4ef6d
Autor:
Nicholas R. Hum, Aimy Sebastian, Kelly A. Martin, Naiomy D. Rios-Arce, Sean F. Gilmore, David M. Gravano, Elizabeth K. Wheeler, Matthew A. Coleman, Gabriela G. Loots
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Due to lack of targetable receptors and intertumoral heterogeneity, triple negative breast cancer (TNBC) remains particularly difficult to treat. Doxorubicin (DOX) is typically used as nonselective neoadjuvant chemotherapy, but the diversity of treat
Externí odkaz:
https://doaj.org/article/c68fb0a68f6b4394a52c6b409b8dbd81
Publikováno v:
Cartilage Tissue Engineering ISBN: 9781071628386
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1120300a29141c9aeedddb597ccc793e
https://doi.org/10.1007/978-1-0716-2839-3_14
https://doi.org/10.1007/978-1-0716-2839-3_14