Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Nicholas R Forsyth"'
Publikováno v:
Journal of Tissue Engineering, Vol 12 (2021)
The human mesenchymal stem cell (hMSC) secretome has pleiotropic effects which underpin their therapeutic potential. hMSC serum-free conditioned media (SFCM) has been determined to contain a variety of cytokines with roles in regeneration and suppres
Externí odkaz:
https://doaj.org/article/df116f228807415783f5c438d985104a
Autor:
Yue‐qing Zhou, Yun Shi, Ling Yang, Yu‐fen Sun, Yu‐fei Han, Zi‐xian Zhao, Yu‐jia Wang, Ying Liu, Yu Ma, Ting Zhang, Tao Ren, Tina P Dale, Nicholas R Forsyth, Fa‐guang Jin, Jie‐ming Qu, Wei Zuo, Jin‐fu Xu
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 1, Pp 1-16 (2019)
Abstract Severe pulmonary infection is a major threat to human health accompanied by substantial medical costs, prolonged inpatient requirements, and high mortality rates. New antimicrobial therapeutic strategies are urgently required to address the
Externí odkaz:
https://doaj.org/article/3ebe6e243af54e25b9c58a499c7dea52
Publikováno v:
Biomaterials and Biosystems, Vol 15, Iss , Pp 100099- (2024)
The bone-cartilage interface is defined by a unique arrangement of cells and tissue matrix. Injury to the interface can contribute to the development of arthritic joint disease. Attempts to repair osteochondral damage through clinical trials have gen
Externí odkaz:
https://doaj.org/article/b691898f9dd44e22a4951bcd93f9e98b
Autor:
Rahul Agrawal, Tina P Dale, Mohammed A Al-Zubaidi, Prit Benny Malgulwar, Nicholas R Forsyth, Ritu Kulshreshtha
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164976 (2016)
MicroRNAs are reported to have a crucial role in the regulation of self-renewal and differentiation of stem cells. Hypoxia has been identified as a key biophysical element of the stem cell culture milieu however, the link between hypoxia and miRNA ex
Externí odkaz:
https://doaj.org/article/3630f53d0867408a8bce41047431c92a
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0133745 (2015)
Limited options for the treatment of cartilage damage have driven the development of tissue engineered or cell therapy alternatives reliant on ex vivo cell expansion. The study of chondrogenesis in primary cells is difficult due to progressive cellul
Externí odkaz:
https://doaj.org/article/bcc6e6d001a146699f5c694d09d85540
Publikováno v:
Carbohydrate Polymer Technologies and Applications, Vol 7, Iss , Pp 100447- (2024)
Rotator cuff injuries affect a large percentage of the population worldwide. Surgical repair has rates of failure of up to 70%, and existing materials used in the reinforcement of injuries often lack appropriate mechanical properties and biodegradabi
Externí odkaz:
https://doaj.org/article/76c518ce91364c29b15aede4ed4bdf79
Publikováno v:
Journal of Tissue Engineering, Vol 3 (2012)
Stem cell therapy may rely on delivery and homing through the vascular system to reach the target tissue. An optical tweezer model has been employed to exert different levels of shear stress on a single non-adherent human bone marrow–derived mesenc
Externí odkaz:
https://doaj.org/article/aa06a7a21868499db87993bcdde393b7
Autor:
Vera Citro, Marta Clerici, Aldo R. Boccaccini, Giovanna Della Porta, Nicola Maffulli, Nicholas R. Forsyth
Publikováno v:
Journal of Tissue Engineering, Vol 14 (2023)
Tendons are dense connective tissues with a hierarchical polarized structure that respond to and adapt to the transmission of muscle contraction forces to the skeleton, enabling motion and maintaining posture. Tendon injuries, also known as tendinopa
Externí odkaz:
https://doaj.org/article/a9f44f5b7d1c47abbdb2eca877f50633
Autor:
Fatma Dogan, Nicholas R. Forsyth
Publikováno v:
Biomolecules, Vol 14, Iss 1, p 131 (2024)
Telomere repeats protect linear chromosomes from degradation, and telomerase has a prominent role in their maintenance. Telomerase has telomere-independent effects on cell proliferation, DNA replication, differentiation, and tumorigenesis. TERT (telo
Externí odkaz:
https://doaj.org/article/45506fec2c714ee6a39572bed785a641
Publikováno v:
Experimental Lung Research. :1-15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06aa2c70c13babdbc22d658432d37eb1
https://doi.org/10.1080/01902148.2022.2158404
https://doi.org/10.1080/01902148.2022.2158404