Zobrazeno 1 - 8 of 8 pro vyhledávání: '"Nicholas Poblete"'
2
Pharmacokinetic and local tissue disposition of [14C]sodium diclofenac following iontophoresis and systemic administration in rabbits
Autor: Xiaoying Hui, Glen L. Xiong, Parminder Singh, Angela Anigbogu, Nicholas Poblete, Howard I. Maibach, Puchun Liu
Publikováno v: Journal of Pharmaceutical Sciences. 90:1269-1276
The systemic pharmacokinetics and local drug distribution of sodium diclofenac in skin and underlying tissues was studied. Iontophoresis facilitated local and systemic delivery of diclofenac sodium compared with passive diffusion. The maximum plasma
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::761f3a025fde5a1853575b5ff4da2fcc
https://doi.org/10.1002/jps.1079
Zobrazit plný text záznamu
3
Stripped skin model to predict irritation potential of topical agents in vivo in humans
Autor: Howard I. Maibach, Hongbo Zhai, Nicholas Poblete
Publikováno v: International Journal of Dermatology. 37:386-389
Background and objective The prediction of the irritation effects of products of low irritation potential remains problematic. An in vivo human model was utilized to define the irritation potential of a topical agent after partial removal of the stra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::490cec7c519831a9da3a12434864d2a1
https://doi.org/10.1046/j.1365-4362.1998.00231.x
Zobrazit plný text záznamu
4
Sodium lauiyl sulphate damaged skin in vivo in man: a water barrier repair model
Autor: Nicholas Poblete, Hongbo Zhai, Howard I. Maibach
Publikováno v: Skin Research and Technology. 4:24-27
Background/aims: Few studies describe enhancing the repair of surfactant-induced damaged skin. In vivo human studies were conducted to evaluate the efficacy of a topical agent after sodium lauryl sulphate (SLS) induced water barrier disruption. Metho
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::454f3ba4554708081b343920624e3070
https://doi.org/10.1111/j.1600-0846.1998.tb00081.x
Zobrazit plný text záznamu
5
[Untitled]
Autor: J Z Shainhouse, Ronald C. Wester, Xiaoying Hui, Howard I. Maibach, Nicholas Poblete, P G Hewitt
Publikováno v: Pharmaceutical Research. 15:1589-1595
Purpose. The primary objective of this study was to determine the rate and extent of transdermal absorption for systemic delivery of diclofenac from Pennsaid (Dimethaid Research, Inc.) topical lotion into the systemic circulation after the lotion was
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f56d61469cff59e8155c3cee736c7acb
https://doi.org/10.1023/a:1011911302005
Zobrazit plný text záznamu
6
[Untitled]
Autor: Ronald C. Wester, J Z Shainhouse, Howard I. Maibach, Nicholas Poblete, P G Hewitt
Publikováno v: Pharmaceutical Research. 15:988-992
Purpose. This study determines comparative bioavailability of diclofenac sodium lotion compared to an aqueous solution after topical application to viable human skin in vitro. In addition, the difference between a single dose and multiple doses (8 ti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6babf19f5d270de6daaaf7316fd0a84f
https://doi.org/10.1023/a:1011961607089
Zobrazit plný text záznamu
7
[Untitled]
Autor: Howard I. Maibach, T. Hartway, Ronald C. Wester, Nicholas Poblete, Julie Christoffel, James Forsell
Publikováno v: Pharmaceutical Research. 15:82-84
Purpose. For decades, human cadaver skin has been banked and utilized by hospitals for burn wounds and to study percutaneous absorption and transdermal delivery. Skin storage maintenance and confirmation of skin viability is important for both uses,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6beedd9b4cf54e91a65dae3f72d51b92
https://doi.org/10.1023/a:1011904921318
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje