Understanding hospital antimicrobial prescribing decisions and determinants of uptake of new local antimicrobial prescribing guidelines in Laos [version 2; peer review: 2 approved]

Autor: Anousone Douangnouvong, Paul Turner, Xaysana Sombandith, Nicholas PJ Day, Peeyanout Thammavongsa, Sommana Rattana, Sommay Keomany, Mayfong Mayxay, Elizabeth A Ashley, Paul N Newton, Vilada Chansamouth, H. Rogier van Doorn

Publikováno v: Wellcome Open Research, Vol 9 (2024)

Background Antimicrobial use in Laos is among the highest in Southeast Asia. The first Lao comprehensive antimicrobial prescribing guidelines have been available since 2021. This study explored the determinants of antibiotic prescribing decisions and

Externí odkaz: https://doaj.org/article/0a9b769939ec4541b568482acd58a72e

Response to comment on 'The clinical pharmacology of tafenoquine in the radical cure of Plasmodium vivax malaria: An individual patient data meta-analysis'

Autor: James A Watson, Robert J Commons, Joel Tarning, Julie A Simpson, Alejandro Llanos Cuentas, Marcus VG Lacerda, Justin A Green, Gavin CKW Koh, Cindy S Chu, François H Nosten, Richard N Price, Nicholas PJ Day, Nicholas J White

Publikováno v: eLife, Vol 13 (2024)

In our recent paper on the clinical pharmacology of tafenoquine (Watson et al., 2022), we used all available individual patient pharmacometric data from the tafenoquine pre-registration clinical efficacy trials to characterise the determinants of ant

Externí odkaz: https://doaj.org/article/a448849101ae42ba942170feabc3d8bf

The clinical pharmacology of tafenoquine in the radical cure of Plasmodium vivax malaria: An individual patient data meta-analysis

Autor: James A Watson, Robert J Commons, Joel Tarning, Julie A Simpson, Alejandro Llanos Cuentas, Marcus VG Lacerda, Justin A Green, Gavin CKW Koh, Cindy S Chu, François H Nosten, Richard N Price, Nicholas PJ Day, Nicholas J White

Publikováno v: eLife, Vol 11 (2022)

Tafenoquine is a newly licensed antimalarial drug for the radical cure of Plasmodium vivax malaria. The mechanism of action and optimal dosing are uncertain. We pooled individual data from 1102 patients and 72 healthy volunteers studied in the pre-re

Externí odkaz: https://doaj.org/article/f5567952f4604510b3632a25a317789f

An open dataset of Plasmodium falciparum genome variation in 7,000 worldwide samples [version 2; peer review: 2 approved]

Autor: MalariaGEN, Ambroise Ahouidi, Mozam Ali, Jacob Almagro-Garcia, Alfred Amambua-Ngwa, Chanaki Amaratunga, Roberto Amato, Lucas Amenga-Etego, Ben Andagalu, Tim J. C. Anderson, Voahangy Andrianaranjaka, Tobias Apinjoh, Cristina Ariani, Elizabeth A Ashley, Sarah Auburn, Gordon A. Awandare, Hampate Ba, Vito Baraka, Alyssa E. Barry, Philip Bejon, Gwladys I. Bertin, Maciej F. Boni, Steffen Borrmann, Teun Bousema, Oralee Branch, Peter C. Bull, George B. J. Busby, Thanat Chookajorn, Kesinee Chotivanich, Antoine Claessens, David Conway, Alister Craig, Umberto D'Alessandro, Souleymane Dama, Nicholas PJ Day, Brigitte Denis, Mahamadou Diakite, Abdoulaye Djimdé, Christiane Dolecek, Arjen M Dondorp, Chris Drakeley, Eleanor Drury, Patrick Duffy, Diego F. Echeverry, Thomas G. Egwang, Berhanu Erko, Rick M. Fairhurst, Abdul Faiz, Caterina A. Fanello, Mark M. Fukuda, Dionicia Gamboa, Anita Ghansah, Lemu Golassa, Sonia Goncalves, William L. Hamilton, G. L. Abby Harrison, Lee Hart, Christa Henrichs, Tran Tinh Hien, Catherine A. Hill, Abraham Hodgson, Christina Hubbart, Mallika Imwong, Deus S. Ishengoma, Scott A. Jackson, Chris G. Jacob, Ben Jeffery, Anna E. Jeffreys, Kimberly J. Johnson, Dushyanth Jyothi, Claire Kamaliddin, Edwin Kamau, Mihir Kekre, Krzysztof Kluczynski, Theerarat Kochakarn, Abibatou Konaté, Dominic P. Kwiatkowski, Myat Phone Kyaw, Pharath Lim, Chanthap Lon, Kovana M. Loua, Oumou Maïga-Ascofaré, Cinzia Malangone, Magnus Manske, Jutta Marfurt, Kevin Marsh, Mayfong Mayxay, Alistair Miles, Olivo Miotto, Victor Mobegi, Olugbenga A. Mokuolu, Jacqui Montgomery, Ivo Mueller, Paul N. Newton, Thuy Nguyen, Thuy-Nhien Nguyen, Harald Noedl, Francois Nosten, Rintis Noviyanti, Alexis Nzila, Lynette I. Ochola-Oyier, Harold Ocholla, Abraham Oduro, Irene Omedo, Marie A. Onyamboko, Jean-Bosco Ouedraogo, Kolapo Oyebola, Richard D. Pearson, Norbert Peshu, Aung Pyae Phyo, Chris V. Plowe, Ric N. Price, Sasithon Pukrittayakamee, Milijaona Randrianarivelojosia, Julian C. Rayner, Pascal Ringwald, Kirk A. Rockett, Katherine Rowlands, Lastenia Ruiz, David Saunders, Alex Shayo, Peter Siba, Victoria J. Simpson, Jim Stalker, Xin-zhuan Su, Colin Sutherland, Shannon Takala-Harrison, Livingstone Tavul, Vandana Thathy, Antoinette Tshefu, Federica Verra, Joseph Vinetz, Thomas E. Wellems, Jason Wendler, Nicholas J. White, Ian Wright, William Yavo, Htut Ye

Publikováno v: Wellcome Open Research, Vol 6 (2021)

MalariaGEN is a data-sharing network that enables groups around the world to work together on the genomic epidemiology of malaria. Here we describe a new release of curated genome variation data on 7,000 Plasmodium falciparum samples from MalariaGEN

Externí odkaz: https://doaj.org/article/6086e8979d4f45dfad3364f4d4f4724a

Defining the burden of febrile illness in rural South and Southeast Asia: an open letter to announce the launch of the Rural Febrile Illness project [version 1; peer review: 2 approved]

Autor: Arjun Chandna, Nan Shwe Nwe Htun, Thomas J Peto, Marco Liverani, Tobias Brummaier, Koukeo Phommasone, Sazid Ibna Zaman, Aye Sandar Zaw, Elizabeth Batty, Naomi Waithira, Melissa Richard-Greenblatt, Stuart D Blacksell, Ladaporn Bodhidatta, James J Callery, Watcharintorn Fagnark, Shayla Islam, Sanchai Lertcharoenchoke, Mavuto Mukaka, Tiengkham Pongvongsa, William HK Schilling, Janjira Thaipadungpanit, Rupam Tripura, Arjen M Dondorp, Mayfong Mayxay, Nicholas J White, Francois Nosten, Frank Smithuis, Elizabeth A Ashley, Richard J Maude, Nicholas PJ Day, Yoel Lubell

Publikováno v: Wellcome Open Research, Vol 6 (2021)

In rural areas of South and Southeast Asia malaria is declining but febrile illnesses still account for substantial morbidity and mortality. Village health workers (VHWs) are often the first point of contact with the formal health system, and for pat

Externí odkaz: https://doaj.org/article/2bc2e2a55dda4d1a8cc8b01d66e64cb8