Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Nicholas Pintori"'
Autor:
Cristina Miliano, Matteo Marti, Nicholas Pintori, Maria Paola Castelli, Micaela Tirri, Raffaella Arfè, Maria Antonietta De Luca
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
4-Iodo-2,5-dimethoxy-N-(2-methoxybenzyl)phenethylamine (25I-NBOMe), commonly called “N-Bomb,” is a synthetic phenethylamine with psychedelic and entactogenic effects; it was available on the Internet both as a legal alternative to lysergic acid d
Externí odkaz:
https://doaj.org/article/dc3e7ecf7ef74944818d74ac1e634777
Autor:
Claudia Sagheddu, Nicholas Pintori, Predrag Kalaba, Vladimir Dragačević, Gessica Piras, Jana Lubec, Nicola Simola, Maria Antonietta De Luca, Gert Lubec, Marco Pistis
Publikováno v:
Biomolecules, Vol 10, Iss 5, p 779 (2020)
Treatments for cognitive impairments associated with neuropsychiatric disorders, such as attention deficit hyperactivity disorder or narcolepsy, aim at modulating extracellular dopamine levels in the brain. CE-123 (5-((benzhydrylsulfinyl)methyl) thia
Externí odkaz:
https://doaj.org/article/2bc9da98571c46c5b7965106ce4c0ddf
Autor:
Sarah Beggiato, Andrea C. Borelli, Maria C. Tomasini, M. Paola Castelli, Nicholas Pintori, Roberto Cacciaglia, Antonella Loche, Luca Ferraro
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
The present study was aimed to further characterize the pharmacological profile of N-[4-(trifluoromethyl) benzyl]-4-methoxybutyramide (GET73), a putative negative allosteric modulator (NAM) of metabotropic glutamate subtype 5 receptor (mGluR5) under
Externí odkaz:
https://doaj.org/article/83d49a9d0a474d91966c64ce034d68b3
Autor:
Nicholas Pintori, Alessandro Piva, Francesca Mottarlini, Fernando Castillo Díaz, Coralie Maggi, Lucia Caffino, Fabio Fumagalli, Cristiano Chiamulera
Environmental enrichment (EE) has been shown to produce beneficial effects in addiction disorders; however, due to its complexity, the underling mechanisms are not yet fully elucidated. Recent evidence suggests that EE, acting as a metaplastic agent,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcb09b445396a0df0f7b7c6cfcd01f02
https://doi.org/10.21203/rs.3.rs-2330791/v1
https://doi.org/10.21203/rs.3.rs-2330791/v1
Autor:
Graziella Tocco, Antonio Laus, Maksims Vanejevs, Anastasija Ture, Rafaela Mostallino, Nicholas Pintori, Maria Antonietta De Luca, M. Paola Castelli, Gaetano Di Chiara
Publikováno v:
Archiv der PharmazieREFERENCES. 356(1)
The development of novel μ-opioid receptor (MOR) antagonists is one of the main objectives of drug discovery and development. Based on a simplified version of the morphinan scaffold, 3-[3-(phenalkylamino)cyclohexyl]phenol analogs were designed, synt
Autor:
Liana Fattore, Marta De Felice, Gaetano Di Chiara, Maria Antonietta De Luca, Marco Pistis, Nicola Simola, Rafaela Mostallino, Claudia Sagheddu, Nicholas Pintori, Cristina Miliano, Maria Scherma, Paola Fadda, Maria Grazia Ennas, Giovanna Flore, Maria Paola Castelli
Publikováno v:
British Journal of Pharmacology
Background and Purpose Spice/K2 herbal mixtures, containing synthetic cannabinoids such as JWH-018, have been marketed as marijuana surrogates since 2004. JWH-018 has cannabinoid CB1 receptor-dependent reinforcing properties and acutely increases dop
Autor:
Giulia Margiani, Maria Paola Castelli, Nicholas Pintori, Roberto Frau, Maria Grazia Ennas, Antonio C. Pagano Zottola, Valeria Orrù, Valentina Serra, Edoardo Fiorillo, Paola Fadda, Giovanni Marsicano, Maria Antonietta De Luca
Publikováno v:
Psychopharmacology. 240:1199-1199
Autor:
Giulia Margiani, Maria Paola Castelli, Nicholas Pintori, Roberto Frau, Maria Grazia Ennas, Antonio C. Pagano Zottola, Valeria Orrù, Valentina Serra, Edoardo Fiorillo, Paola Fadda, Giovanni Marsicano, Maria Antonietta De Luca
Publikováno v:
Psychopharmacology
Psychopharmacology, 2022, 239 (10), pp.3083-3102. ⟨10.1007/s00213-022-06191-9⟩
Psychopharmacology, 2022, 239 (10), pp.3083-3102. ⟨10.1007/s00213-022-06191-9⟩
Rationale The use of synthetic cannabinoid receptor agonists (SCRAs) is growing among adolescents, posing major medical and psychiatric risks. JWH-018 represents the reference compound of SCRA-containing products. Objectives This study was performed
Chronic Environmental Enrichment (EE) has been shown to prevent the relapse to addictive behaviours , such as drug-taking and -seeking. Recently, acute EE was shown to reduce cue-induced sucrose-seeking, but its effects on contextual (Cx)-induced suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5a290224b5bcc7af19faabe4126f8e8
http://hdl.handle.net/11562/1048178
http://hdl.handle.net/11562/1048178
Autor:
Maria Antonietta De Luca, Graziella Tocco, Rafaela Mostallino, Antonio Laus, Francesca Caria, Aurora Musa, Nicholas Pintori, Marcos Ucha, Celia Poza, Emilio Ambrosio, Gaetano Di Chiara, M. Paola Castelli
Publikováno v:
Neuropharmacology. 221:109263
Recent trends of opioid abuse and related fatalities have highlighted the critical role of Novel Synthetic Opioids (NSOs). We studied the μ-opioid-like properties of isotonitazene (ITZ), metonitazene (MTZ), and piperidylthiambutene (PTB) using diffe