Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Nicholas Phillip Mulholland"'
Autor:
Silvia De Cesare, Juraj Bella, Lorna Murray, Nicholas Phillip Mulholland, Catherine A McKenna, Dominic J. Campopiano
Publikováno v:
De Cesare, S, Mckenna, C A, Mulholland, N, Murray, L, Bella, J & Campopiano, D J 2021, ' Direct monitoring of biocatalytic deacetylation of amino acid substrates by 1 H NMR reveals fine details of substrate specificity ', Organic & Biomolecular chemistry . https://doi.org/10.1039/D1OB00122A
Amino acids are key synthetic building blocks that can be prepared in an enantiopure form by biocatalytic methods. We show that the l-selective ornithine deacetylase ArgE catalyses hydrolysis of a wide-range of N-acyl-amino acid substrates. This acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36ca8c0427e36516262469e99317fa26
https://www.pure.ed.ac.uk/ws/files/210968070/20210520_Campopiano_d1ob00122a.pdf
https://www.pure.ed.ac.uk/ws/files/210968070/20210520_Campopiano_d1ob00122a.pdf
Autor:
Kate M. J. de Mattos-Shipley, Christine L. Willis, Andy M. Bailey, Trong Tuan Dao, Zhongshu Song, David M. Heard, Nicholas Phillip Mulholland, Daniel E. O’Flynn, Claudio Greco, Thomas J. Simpson, Catherine E Spencer, Russell J. Cox, Jason Leigh Vincent
Publikováno v:
De Mattos-Shipley, K M J, Spencer, C E, Greco, C, Heard, D M, O'Flynn, D E, Dao, T T, Song, Z, Mullholland, N P, Vincent, J L, Simpson, T J, Cox, R J, Bailey, A M & Willis, C L 2020, ' Uncovering Biosynthetic Relationships Between Antifungal Nonadrides and Octadrides ', Chemical Science, vol. 11, pp. 11570-11578 . https://doi.org/10.1039/D0SC04309E
Chemical Science 11 (2020), Nr. 42
Chemical Science
Chemical Science 11 (2020), Nr. 42
Chemical Science
Maleidrides are a class of bioactive secondary metabolites unique to filamentous fungi, which contain one or more maleic anhydrides fused to a 7-, 8- or 9- membered carbocycle (named heptadrides, octadrides and nonadrides respectively). Herein struct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3445f4bc2a57393a14f8131fb4a86a04
https://research-information.bris.ac.uk/ws/files/254590048/d0sc04309e.pdf
https://research-information.bris.ac.uk/ws/files/254590048/d0sc04309e.pdf
Autor:
Nicholas Phillip Mulholland, Kate M. J. de Mattos-Shipley, Claudio Greco, Thomas J. Simpson, Jason Leigh Vincent, Christine L. Willis, Andy M. Bailey, Russell J. Cox
Publikováno v:
Greco, C, de Mattos-Shipley, K, Bailey, A M, Mulholland, N P, Vincent, J L, Willis, C L, Cox, R J & Simpson, T J 2019, ' Structure revision of cryptosporioptides and determination of the genetic basis for dimeric xanthone biosynthesis in fungi ', Chemical Science, vol. 10, no. 10, pp. 2930-2939 . https://doi.org/10.1039/c8sc05126g
Chemical Science
Chemical Science (2019), Nr. 10
Chemical Science
Chemical Science (2019), Nr. 10
Three novel dimeric xanthones, cryptosporioptides A–C were isolated from Cryptosporiopsis sp. 8999 and their structures elucidated.
Three novel dimeric xanthones, cryptosporioptides A–C were isolated from Cryptosporiopsis sp. 8999 and their
Three novel dimeric xanthones, cryptosporioptides A–C were isolated from Cryptosporiopsis sp. 8999 and their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96a88ad6479ed4516fe27272ca573f7d
http://www.scopus.com/inward/record.url?scp=85062593645&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85062593645&partnerID=8YFLogxK
Autor:
Christine L. Willis, Thomas J. Simpson, Jason Leigh Vincent, Russell J. Cox, Agnieszka J. Szwalbe, Katherine Williams, Andy M. Bailey, Nicholas Phillip Mulholland
Publikováno v:
Angewandte Chemie. 128:6896-6900
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abcff610727b74606815e337ff357c1f
https://doi.org/10.1002/ange.201511882
https://doi.org/10.1002/ange.201511882
Autor:
Agnieszka J. Szwalbe, Russell J. Cox, Claire L. Dickson, Jason Leigh Vincent, Christine L. Willis, Katherine Williams, Tim R. Desson, Nicholas Phillip Mulholland, John Martin Clough, Thomas J. Simpson, Craig P. Butts, Andy M. Bailey
Publikováno v:
Williams, K, Szwalbe, A J, Dickson, C, Desson, T R, Mulholland, N P, Vincent, J L, Clough, J M, Bailey, A M, Butts, C P, Willis, C L, Simpson, T J & Cox, R J 2017, ' Genetic and chemical characterisation of the cornexistin pathway provides further insight into maleidride biosynthesis ', Chemical Communications, vol. 53, no. 56, pp. 7965-7968 . https://doi.org/10.1039/c7cc03303f
The biosynthesis of the herbicide cornexistin in the fungus Paecilomyces variotii was investigated by full sequencing of its genome, knockout of key genes within its biosynthetic gene cluster and isolation and identification of intermediate compounds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23c206df90fa697f8c2ed8f2653f2125
https://research-information.bris.ac.uk/ws/files/181842682/Cornexistin_Chem_Comm_RJC9_KW.pdf
https://research-information.bris.ac.uk/ws/files/181842682/Cornexistin_Chem_Comm_RJC9_KW.pdf
Autor:
Agnieszka J. Szwalbe, Russell J. Cox, Thomas J. Simpson, Katherine Williams, Christine L. Willis, Nicholas Phillip Mulholland, Andy M. Bailey, Jason Leigh Vincent
Publikováno v:
Williams, K, Szwalbe, A J, Mulholland, N P, Vincent, J L, Bailey, A, Willis, C L, Simpson, T J & Cox, R J 2016, ' Heterologous Production of Fungal Maleidrides Reveals the Cryptic Cyclization Involved in their Biosynthesis ', Angewandte Chemie-International Edition, vol. 55, no. 23, pp. 6784-6788 . https://doi.org/10.1002/anie.201511882
Angewandte Chemie (International Ed. in English)
Angewandte Chemie-International Edition 55 (2016), Nr. 23
Angewandte Chemie (International Ed. in English)
Angewandte Chemie-International Edition 55 (2016), Nr. 23
Fungal maleidrides are an important family of bioactive secondary metabolites that consist of 7, 8, or 9-membered carbocycles with one or two fused maleic anhydride moieties. The biosynthesis of byssochlamic acid (a nonadride) and agnestadride A (a h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7edd9c6b6f4b3f818427be2fe29ead3
https://research-information.bris.ac.uk/ws/files/88777449/anie201511882_sup_0001_misc_information.pdf
https://research-information.bris.ac.uk/ws/files/88777449/anie201511882_sup_0001_misc_information.pdf
Autor:
Andy M. Bailey, Nicholas Phillip Mulholland, Katherine Williams, Jason Leigh Vincent, Thomas J. Simpson, Christine L. Willis, Agnieszka J. Szwalbe, Daniel E. O’Flynn, Russell J. Cox
Publikováno v:
Chemical Communications (2015)
Szwalbe, A J, Williams, K, O'Flynn, D E, Bailey, A M, Mulholland, N P, Vincent, J L, Willis, C L, Cox, R J & Simpson, T J 2015, ' Novel nonadride, heptadride and maleic acid metabolites from the byssochlamic acid producer Byssochlamys fulva IMI 40021 – an insight into the biosynthesis of maleidrides ', Chemical Communications, vol. 51, no. 96, pp. 17088-17091 . https://doi.org/10.1039/C5CC06988B
Szwalbe, A J, Williams, K, O'Flynn, D E, Bailey, A M, Mulholland, N P, Vincent, J L, Willis, C L, Cox, R J & Simpson, T J 2015, ' Novel nonadride, heptadride and maleic acid metabolites from the byssochlamic acid producer Byssochlamys fulva IMI 40021 – an insight into the biosynthesis of maleidrides ', Chemical Communications, vol. 51, no. 96, pp. 17088-17091 . https://doi.org/10.1039/C5CC06988B
The filamentous fungus Byssochlamys fulva strain IMI 40021 produces (+)-byssochlamic acid 1, its novel dihydroanalogue 2 and four related secondary metabolites. Agnestadrides A, 17 and B, 18 constitute a novel class of seven-membered ring, maleic anh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8b7a1e859b8b8c51624dbd5a91455ef
http://www.repo.uni-hannover.de/handle/123456789/177
http://www.repo.uni-hannover.de/handle/123456789/177