Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Nicholas Papadopoulos"'
Autor:
Jeanne Tie, Yuxuan Wang, Joshua Cohen, Lu Li, Wei Hong, Michael Christie, Hui Li Wong, Suzanne Kosmider, Rachel Wong, Benjamin Thomson, Julian Choi, Adrian Fox, Kathryn Field, Matthew Burge, Jenny Shannon, Dusan Kotasek, Niall C Tebbutt, Christos Karapetis, Craig Underhill, Andrew Haydon, Joy Schaeffer, Janine Ptak, Cristian Tomasetti, Nicholas Papadopoulos, Kenneth W Kinzler, Bert Vogelstein, Peter Gibbs
Publikováno v:
PLoS Medicine, Vol 18, Iss 5, p e1003620 (2021)
BackgroundIn patients with resectable colorectal liver metastases (CRLM), the role of pre- and postoperative systemic therapy continues to be debated. Previous studies have shown that circulating tumor DNA (ctDNA) analysis, as a marker of minimal res
Externí odkaz:
https://doaj.org/article/5fefae544f494349b57c0bd567ac52e2
Autor:
Jeanne, Tie, Joshua D, Cohen, Kamel, Lahouel, Serigne N, Lo, Yuxuan, Wang, Suzanne, Kosmider, Rachel, Wong, Jeremy, Shapiro, Margaret, Lee, Sam, Harris, Adnan, Khattak, Matthew, Burge, Marion, Harris, James, Lynam, Louise, Nott, Fiona, Day, Theresa, Hayes, Sue-Anne, McLachlan, Belinda, Lee, Janine, Ptak, Natalie, Silliman, Lisa, Dobbyn, Maria, Popoli, Ralph, Hruban, Anne Marie, Lennon, Nicholas, Papadopoulos, Kenneth W, Kinzler, Bert, Vogelstein, Cristian, Tomasetti, Peter, Gibbs, Susanne, Kosmider
Publikováno v:
New England Journal of Medicine. 386:2261-2272
The role of adjuvant chemotherapy in stage II colon cancer continues to be debated. The presence of circulating tumor DNA (ctDNA) after surgery predicts very poor recurrence-free survival, whereas its absence predicts a low risk of recurrence. The be
Autor:
Patrick Hwu, Audrey Gonzalez, Seth Wardell, Renjith Ramachandran, Christopher Toth, Orenthial J. Fulbright, Rahmatu Mansaray, Michael A. Davies, Janice N. Cormier, Richard Royal, Anthony Lucci, Jeffrey E. Gershenwald, Jeffrey E. Lee, Merrick I. Ross, Sapna Patel, Wen-Jen Hwu, Agop Bedikian, Jade Homsi, Kevin Kim, Nicholas Papadopoulos, Victor Prieto, Elizabeth Shpall, John D. McMannis, Valen E. Johnson, Michelle Glass, Gladys Alvarado, Sandy Mahoney, Gregory Lizee, Richard Wu, Jessica Chacon, Priscilla Miller, Patricia S. Fox, Minying Zhang, Chantale Bernatchez, Laszlo G. Radvanyi
PDF file - 77K, Long term changes in the persistence of TCR Vβ clonotypes in the blood following TIL adoptive transfer in representative responding patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::390ecb78d757847657a3084e230971eb
https://doi.org/10.1158/1078-0432.22452170.v1
https://doi.org/10.1158/1078-0432.22452170.v1
Autor:
Patrick Hwu, Audrey Gonzalez, Seth Wardell, Renjith Ramachandran, Christopher Toth, Orenthial J. Fulbright, Rahmatu Mansaray, Michael A. Davies, Janice N. Cormier, Richard Royal, Anthony Lucci, Jeffrey E. Gershenwald, Jeffrey E. Lee, Merrick I. Ross, Sapna Patel, Wen-Jen Hwu, Agop Bedikian, Jade Homsi, Kevin Kim, Nicholas Papadopoulos, Victor Prieto, Elizabeth Shpall, John D. McMannis, Valen E. Johnson, Michelle Glass, Gladys Alvarado, Sandy Mahoney, Gregory Lizee, Richard Wu, Jessica Chacon, Priscilla Miller, Patricia S. Fox, Minying Zhang, Chantale Bernatchez, Laszlo G. Radvanyi
PDF file - 58K, Demographics and clinical characteristics of enrolled patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16880fbde58598a94efc84f02ee6ed30
https://doi.org/10.1158/1078-0432.22452182
https://doi.org/10.1158/1078-0432.22452182
Autor:
Patrick Hwu, Audrey Gonzalez, Seth Wardell, Renjith Ramachandran, Christopher Toth, Orenthial J. Fulbright, Rahmatu Mansaray, Michael A. Davies, Janice N. Cormier, Richard Royal, Anthony Lucci, Jeffrey E. Gershenwald, Jeffrey E. Lee, Merrick I. Ross, Sapna Patel, Wen-Jen Hwu, Agop Bedikian, Jade Homsi, Kevin Kim, Nicholas Papadopoulos, Victor Prieto, Elizabeth Shpall, John D. McMannis, Valen E. Johnson, Michelle Glass, Gladys Alvarado, Sandy Mahoney, Gregory Lizee, Richard Wu, Jessica Chacon, Priscilla Miller, Patricia S. Fox, Minying Zhang, Chantale Bernatchez, Laszlo G. Radvanyi
PDF file - 1856K, Fig. S1. Schema of TIL adoptive cell therapy clinical trial; Fig. S2. Recovery of total white blood cell counts (WBC), absolute lymphocyte counts (ALC), and absolute neutrophil counts (ANC) during adoptive transfer TIL therapy in 31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20f6791d55d97adb8fa30f538cad74a5
https://doi.org/10.1158/1078-0432.22452188.v1
https://doi.org/10.1158/1078-0432.22452188.v1
Autor:
Michael A. Davies, Gordon B. Mills, Patrick Hwu, Nicholas Papadopoulos, Kevin B. Kim, Doina Ivan, Donald A. Podoloff, Dan Yang, Y.N. Vashisht Gopal, Maurizio Fermeglia, Giovanni M. Pavan, Sabrina Pricl, Alexander J. Lazar, Katherine Stemke-Hale, Jonathan C. Trent, Scott E. Woodman
Supplementary Table, Materials and References from Activity of dasatinib against L576P KIT mutant melanoma: Molecular, cellular, and clinical correlates
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ffab3409774f9bb373bee5f81204929
https://doi.org/10.1158/1535-7163.22484840
https://doi.org/10.1158/1535-7163.22484840
Autor:
Patrick Hwu, Audrey Gonzalez, Seth Wardell, Renjith Ramachandran, Christopher Toth, Orenthial J. Fulbright, Rahmatu Mansaray, Michael A. Davies, Janice N. Cormier, Richard Royal, Anthony Lucci, Jeffrey E. Gershenwald, Jeffrey E. Lee, Merrick I. Ross, Sapna Patel, Wen-Jen Hwu, Agop Bedikian, Jade Homsi, Kevin Kim, Nicholas Papadopoulos, Victor Prieto, Elizabeth Shpall, John D. McMannis, Valen E. Johnson, Michelle Glass, Gladys Alvarado, Sandy Mahoney, Gregory Lizee, Richard Wu, Jessica Chacon, Priscilla Miller, Patricia S. Fox, Minying Zhang, Chantale Bernatchez, Laszlo G. Radvanyi
PDF file - 69K, Derivation of the irRC best overall score
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f2a3220cb42bd11670fd4c9bf952dd9
https://doi.org/10.1158/1078-0432.22452179
https://doi.org/10.1158/1078-0432.22452179
Autor:
Patrick Hwu, Audrey Gonzalez, Seth Wardell, Renjith Ramachandran, Christopher Toth, Orenthial J. Fulbright, Rahmatu Mansaray, Michael A. Davies, Janice N. Cormier, Richard Royal, Anthony Lucci, Jeffrey E. Gershenwald, Jeffrey E. Lee, Merrick I. Ross, Sapna Patel, Wen-Jen Hwu, Agop Bedikian, Jade Homsi, Kevin Kim, Nicholas Papadopoulos, Victor Prieto, Elizabeth Shpall, John D. McMannis, Valen E. Johnson, Michelle Glass, Gladys Alvarado, Sandy Mahoney, Gregory Lizee, Richard Wu, Jessica Chacon, Priscilla Miller, Patricia S. Fox, Minying Zhang, Chantale Bernatchez, Laszlo G. Radvanyi
PDF file - 115K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23947fc80f4534d59ef0e49b90e97e01
https://doi.org/10.1158/1078-0432.22452185
https://doi.org/10.1158/1078-0432.22452185
Autor:
Michael A. Davies, Gordon B. Mills, Patrick Hwu, Nicholas Papadopoulos, Kevin B. Kim, Doina Ivan, Donald A. Podoloff, Dan Yang, Y.N. Vashisht Gopal, Maurizio Fermeglia, Giovanni M. Pavan, Sabrina Pricl, Alexander J. Lazar, Katherine Stemke-Hale, Jonathan C. Trent, Scott E. Woodman
Point mutations in the KIT receptor tyrosine kinase gene have recently been identified in mucosal, acral lentiginous, and chronically sun-damaged melanomas. We have identified the first human melanoma cell line with an endogenous L576P mutation, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e4841603282362d5fdac3ee08df00c0
https://doi.org/10.1158/1535-7163.c.6531608
https://doi.org/10.1158/1535-7163.c.6531608
Autor:
Patrick Hwu, Audrey Gonzalez, Seth Wardell, Renjith Ramachandran, Christopher Toth, Orenthial J. Fulbright, Rahmatu Mansaray, Michael A. Davies, Janice N. Cormier, Richard Royal, Anthony Lucci, Jeffrey E. Gershenwald, Jeffrey E. Lee, Merrick I. Ross, Sapna Patel, Wen-Jen Hwu, Agop Bedikian, Jade Homsi, Kevin Kim, Nicholas Papadopoulos, Victor Prieto, Elizabeth Shpall, John D. McMannis, Valen E. Johnson, Michelle Glass, Gladys Alvarado, Sandy Mahoney, Gregory Lizee, Richard Wu, Jessica Chacon, Priscilla Miller, Patricia S. Fox, Minying Zhang, Chantale Bernatchez, Laszlo G. Radvanyi
PDF file - 76k, Table S3. Associations between categorical patient variables and clinical response; Table S4. Associations between continuous variables and clinical response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6889dd28004a455a4b7fca9b2a53aeb8
https://doi.org/10.1158/1078-0432.22452173
https://doi.org/10.1158/1078-0432.22452173