Zobrazeno 1 - 10
of 179
pro vyhledávání: '"Nicholas P. Tatonetti"'
Autor:
Jenna Kefeli, Jacob Berkowitz, Jose M. Acitores Cortina, Kevin K. Tsang, Nicholas P. Tatonetti
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-7 (2024)
Abstract Cancer staging is an essential clinical attribute informing patient prognosis and clinical trial eligibility. However, it is not routinely recorded in structured electronic health records. Here, we present BB-TEN: Big Bird – TNM staging Ex
Externí odkaz:
https://doaj.org/article/375869de715546538fec10b70e5b6fee
Autor:
Kathleen LaRow Brown, Vijendra Ramlall, Michael Zietz, Undina Gisladottir, Nicholas P. Tatonetti
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-7 (2024)
Abstract SARS-CoV-2 has infected over 340 million people, prompting therapeutic research. While genetic studies can highlight potential drug targets, understanding the heritability of SARS-CoV-2 susceptibility and COVID-19 severity can contextualize
Externí odkaz:
https://doaj.org/article/ca2d0a450d174afaaf13292d770c4e4c
Autor:
Celine M. Schreidah, Emily R. Gordon, Oluwaseyi Adeuyan, Caroline Chen, Brigit A. Lapolla, Joshua A. Kent, George Bingham Reynolds, Lauren M. Fahmy, Chunhua Weng, Nicholas P. Tatonetti, Herbert S. Chase, Itsik Pe’er, Larisa J. Geskin
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Skin cancer mortality rates continue to rise, and survival analysis is increasingly needed to understand who is at risk and what interventions improve outcomes. However, current statistical methods are limited by inability to synthesize multiple data
Externí odkaz:
https://doaj.org/article/645da4e01a6e4dfe8d2990e3a7d08497
Autor:
Nicholas P. Giangreco, Guillaume Lebreton, Susan Restaino, Maryjane Farr, Emmanuel Zorn, Paolo C. Colombo, Jignesh Patel, Rajesh Kumar Soni, Pascal Leprince, Jon Kobashigawa, Nicholas P. Tatonetti, Barry M. Fine
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Heart transplantation remains the definitive treatment for end stage heart failure. Because availability is limited, risk stratification of candidates is crucial for optimizing both organ allocations and transplant outcomes. Here we utilize
Externí odkaz:
https://doaj.org/article/6446af2595e543f99511c9b5f7256dd6
Autor:
Shayan Dioun, Ling Chen, Grace Hillyer, Nicholas P. Tatonetti, Benjamin L. May, Alexander Melamed, Jason D. Wright
Publikováno v:
Cancer Reports, Vol 6, Iss 2, Pp n/a-n/a (2023)
Abstract Background Racial and ethnic minority groups experience a disproportionate burden of SARS‐CoV‐2 illness and studies suggest that cancer patients are at a particular risk for severe SARS‐CoV‐2 infection. Aims The objective of this stu
Externí odkaz:
https://doaj.org/article/cb482364aa504e29b1cae9579322ff18
Autor:
Joseph D. Romano, Hai Li, Tanya Napolitano, Ronald Realubit, Charles Karan, Mandë Holford, Nicholas P. Tatonetti
Publikováno v:
Toxins, Vol 15, Iss 7, p 451 (2023)
Venoms are a diverse and complex group of natural toxins that have been adapted to treat many types of human disease, but rigorous computational approaches for discovering new therapeutic activities are scarce. We have designed and validated a new pl
Externí odkaz:
https://doaj.org/article/8f0a7c2f2e8647bbb7089de9ccb97f3a
Publikováno v:
BioData Mining, Vol 14, Iss 1, Pp 1-17 (2021)
Abstract Background Identifying adverse drugs effects (ADEs) in children, overall and within pediatric age groups, is essential for preventing disability and death from marketed drugs. At the same time, however, detection is challenging due to dynami
Externí odkaz:
https://doaj.org/article/19859631776948fd94c9c1752e022dc6
Autor:
Peter J. Kennel, Alexandre Yahi, Yoshifumi Naka, Donna M. Mancini, Charles C. Marboe, Klaas Max, Kemal Akat, Thomas Tuschl, Elena‐Rodica M. Vasilescu, Emmanuel Zorn, Nicholas P. Tatonetti, Paul Christian Schulze
Publikováno v:
ESC Heart Failure, Vol 8, Iss 3, Pp 1840-1849 (2021)
Abstract Aims Allograft rejection following heart transplantation (HTx) is a serious complication even in the era of modern immunosuppressive regimens and causes up to a third of early deaths after HTx. Allograft rejection is mediated by a cascade of
Externí odkaz:
https://doaj.org/article/66200cfdc2294501b63990a52ca95854
Autor:
Ning Shang, Atlas Khan, Fernanda Polubriaginof, Francesca Zanoni, Karla Mehl, David Fasel, Paul E. Drawz, Robert J. Carrol, Joshua C. Denny, Matthew A. Hathcock, Adelaide M. Arruda-Olson, Peggy L. Peissig, Richard A. Dart, Murray H. Brilliant, Eric B. Larson, David S. Carrell, Sarah Pendergrass, Shefali Setia Verma, Marylyn D. Ritchie, Barbara Benoit, Vivian S. Gainer, Elizabeth W. Karlson, Adam S. Gordon, Gail P. Jarvik, Ian B. Stanaway, David R. Crosslin, Sumit Mohan, Iuliana Ionita-Laza, Nicholas P. Tatonetti, Ali G. Gharavi, George Hripcsak, Chunhua Weng, Krzysztof Kiryluk
Publikováno v:
npj Digital Medicine, Vol 4, Iss 1, Pp 1-13 (2021)
Abstract Chronic Kidney Disease (CKD) represents a slowly progressive disorder that is typically silent until late stages, but early intervention can significantly delay its progression. We designed a portable and scalable electronic CKD phenotype to
Externí odkaz:
https://doaj.org/article/24b3c498eb59459db6ee0b4a55ddf3e3
Autor:
Phyllis M. Thangaraj, Benjamin R. Kummer, Tal Lorberbaum, Mitchell S. V. Elkind, Nicholas P. Tatonetti
Publikováno v:
BioData Mining, Vol 13, Iss 1, Pp 1-14 (2020)
Abstract Background Accurate identification of acute ischemic stroke (AIS) patient cohorts is essential for a wide range of clinical investigations. Automated phenotyping methods that leverage electronic health records (EHRs) represent a fundamentall
Externí odkaz:
https://doaj.org/article/55521d33ae5e4f7883eec599611d409a