Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Nicholas P. J. Brindle"'
Autor:
Deborah O. A. Alawo, Tariq A. Tahir, Marlies Fischer, Declan G. Bates, Svetlana R. Amirova, Nicholas P. J. Brindle
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Angiopoietin-1 (Angpt1) is a glycoprotein ligand important for maintaining the vascular system. It signals via a receptor tyrosine kinase expressed on the surface on endothelial cells, Tie2. This receptor can undergo regulated ectodomain cle
Externí odkaz:
https://doaj.org/article/d67adf71f1c94acdaa76476210bf82b7
Autor:
Neil Bate, Christos G. Savva, Peter C. E. Moody, Edward A. Brown, Sian E. Evans, Jonathan K. Ball, John W. R. Schwabe, Julian E. Sale, Nicholas P. J. Brindle
Publikováno v:
PLoS pathogens. 18(7)
Emerging SARS-CoV-2 variants are creating major challenges in the ongoing COVID-19 pandemic. Being able to predict mutations that could arise in SARS-CoV-2 leading to increased transmissibility or immune evasion would be extremely valuable in develop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d1da5381f98f865f0fa99a86f842472
https://pubmed.ncbi.nlm.nih.gov/35849637
https://pubmed.ncbi.nlm.nih.gov/35849637
Autor:
Nicholas P J Brindle
Publikováno v:
Eye. 9:167-172
Following transplantation endothelial cells lining an allograft come into contact with immune cells of the recipient. Activation of an immune response, by graft endothelial or other cells, will lead to local increases in cytokine production and cell-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5041c50149bb17721ac1e9280af3cc6
https://doi.org/10.1038/eye.1995.34
https://doi.org/10.1038/eye.1995.34
Autor:
Nicholas P. J. Brindle
Publikováno v:
Cardiovascular Research. 27:1162-1172
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a23022fc7929f69ccc760ad5528d19dd
https://doi.org/10.1093/cvr/27.7.1162
https://doi.org/10.1093/cvr/27.7.1162
Publikováno v:
Biochemical Journal. 280:99-104
The role of insulin in the regulation of plasma triacylglycerol is poorly understood. Conflicting actions of insulin on rat liver cells have been reported, insulin inhibiting triacylglycerol secretion in short incubations (less than 24 h) and stimula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5125ca7f696f4a62e56568e9993ca0ab
https://doi.org/10.1042/bj2800099
https://doi.org/10.1042/bj2800099
Publikováno v:
International journal of oncology. 31(4)
The receptor tyrosine kinase Tie1 is expressed primarily in vascular endothelial cells. The receptor has also been detected in epithelial tumours in breast, thyroid and gastric cancers and in tumour cell lines where it appears as a 45 kDa truncated r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d74e344fc33646e0b5b0c5fe1039e19
https://pubmed.ncbi.nlm.nih.gov/17786322
https://pubmed.ncbi.nlm.nih.gov/17786322
1. We studied the effect of two structurally-related, selective inhibitors of protein kinase C, Ro 31-8220 and Ro 31-7549, on the reinitiation of proliferation in quiescent first passage rabbit aortic smooth muscle cells in response to (a) the direct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::383c3e8368701439724469a9a3a98d84
https://europepmc.org/articles/PMC1510373/
https://europepmc.org/articles/PMC1510373/
Publikováno v:
Growth Factors and the Cardiovascular System ISBN: 9781461363545
Proliferation of vascular smooth muscle cells (VSMC) is a characteristic feature of repair following vascular injury and adaptation to increased intraluminal pressure such as occurs in arteriovenous fistulas and in pulmonary hypertension. The intimai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::630c29abd401f5da41c7c55608cb5faf
https://doi.org/10.1007/978-1-4615-3098-5_12
https://doi.org/10.1007/978-1-4615-3098-5_12
Publikováno v:
Biochemical Society Transactions. 26:S365-S365
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95227df089a55b6cffbaac233776c2dc
https://doi.org/10.1042/bst026s365
https://doi.org/10.1042/bst026s365
Publikováno v:
Biochemical Society Transactions. 21:436S-436S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d15cb8d8d960990745d1751d23c23525
https://doi.org/10.1042/bst021436s
https://doi.org/10.1042/bst021436s