Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Nicholas P. Ho"'
Autor:
Shyam H. Kamble, Samuel Obeng, Francisco León, Luis F. Restrepo, Tamara I. King, Erin C. Berthold, Siva Rama Raju Kanumuri, Lea R. Gamez-Jimenez, Victoria L.C. Pallares, Avi Patel, Nicholas P. Ho, Aidan Hampson, Christopher R. McCurdy, Lance R. McMahon, Jenny L. Wilkerson, Abhisheak Sharma, Takato Hiranita
Publikováno v:
J Pharmacol Exp Ther
Mitragynine, an opioidergic alkaloid present in Mitragyna speciosa (kratom), is metabolized by cytochrome P450 3A (CYP3A) to 7-hydroxymitragynine, a more potent opioid receptor agonist. The extent to which conversion to 7-hydroxymitragynine mediates
Autor:
Samuel Obeng, Francisco Leon, Avi Patel, Julio D. Zuarth Gonzalez, Lucas Chaves Da Silva, Luis F. Restrepo, Lea R. Gamez-Jimenez, Nicholas P. Ho, Maria P. Guerrero Calvache, Victoria L.C. Pallares, Justin A. Helmes, Sakura K. Shiomitsu, Paul L. Soto, Aidan J. Hampson, Christopher R. McCurdy, Lance R. McMahon, Jenny L. Wilkerson, Takato Hiranita
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 383:182-198
Publikováno v:
ASPET 2023 Annual Meeting Abstract - Central Nervous System Pharmacology - Neuropharmacology.
Autor:
Takato Hiranita, Julio Zuarth Gonzalez, Rohan C. Patel, Christian C. Mazpule‐Carrigan, Joelma Martins Rocha, Lea R. Gamez Jimenez, Nicholas P. Ho, Avi Patel, Samuel Obeng, Francisco Leon, Marco Mottinelli, Sushobhan Mukhopadhyay, Christopher R. McCurdy, Lance R. McMahon
Publikováno v:
The FASEB Journal. 36
Autor:
Victoria L.C. Pallares, Anna E. Pennington, Morgan L. Crowley, Avi Patel, Morgan E. Reeves, Carolina Lopera-Londoño, Marco Mottinelli, Nicholas P. Ho, Francisco León, John D. Fortner, Christopher R. McCurdy, Luis F. Restrepo, Victoria A. Taylor, Jenny L. Wilkerson, Lance R. McMahon, Samuel Obeng, Takato Hiranita, Tobias Braun, Lea R. Gamez-Jimenez, Morgan R. Williamson
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 376:410-427
Relationships between µ-opioid receptor (MOR) efficacy and effects of mitragynine and 7-hydroxymitragynine are not fully established. We assessed in vitro binding affinity and efficacy and discriminative stimulus effects together with antinociceptio
Autor:
Samuel, Obeng, Francisco, Leon, Avi, Patel, Julio D, Zuarth Gonzalez, Lucas, Chaves Da Silva, Luis F, Restrepo, Lea R, Gamez-Jimenez, Nicholas P, Ho, Maria P, Guerrero Calvache, Victoria L C, Pallares, Justin A, Helmes, Sakura K, Shiomitsu, Paul L, Soto, Christopher R, McCurdy, Lance R, McMahon, Jenny L, Wilkerson, Takato, Hiranita
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 383(3)
The primary kratom alkaloid mitragynine is proposed to act through multiple mechanisms, including actions at
Autor:
Maria P Guerrero Calvache, Samuel Obeng, Francisco Leon, Lea R Gamez‐Jimenez, Avi Patel, Nicholas P Ho, Morgan L Crowley, Victoria Pallares, Marco Mottinelli, Christopher R McCurdy, Lance R McMahon, Takato Hiranita
Publikováno v:
Alzheimer's & Dementia. 17
Autor:
Lea R. Gamez-Jimenez, Lance R. McMahon, Nicholas P. Ho, Julio Zuarth Gonzalez, Victoria L.C. Pallares, Amsha Thadisetti, Marco Mottinelli, Christopher R. McCurdy, Morgan L. Crowley, Manuel G. Alvarez, Takato Hiranita, Samuel Obeng, Avi Patel, Elizabeth Kern, Luis F. Restrepo, Francisco León
Publikováno v:
The FASEB Journal. 35
Autor:
Takato Hiranita, Julio Zuarth Gonzalez, Francisco León, Lance R. McMahon, Avi Patel, Marco Mottinelli, Christopher R. McCurdy, Lea R. Gamez Jimenez, Megan Patel, Nicholas P. Ho, Rohan Patel
Publikováno v:
The FASEB Journal. 35
Autor:
Manuel Alvarez, Julio Zuarth Gonzalez, Samuel Obeng, Francisco León, Elizabeth Kern, Nicholas P. Ho, Lance R. McMahon, Amsha Thadisetti, Marco Mottinelli, Christopher R. McCurdy, Lea R. Gamez-Jimenez, Avi Patel, Takato Hiranita
Publikováno v:
The FASEB Journal. 35