Zobrazeno 1 - 10
of 157
pro vyhledávání: '"Nicholas P. Cianciotto"'
Autor:
Saima Rehman, Anna Katarina Antonovic, Ian E. McIntire, Huaixin Zheng, Leanne Cleaver, Maria Baczynska, Carlton O. Adams, Theo Portlock, Katherine Richardson, Rosie Shaw, Alain Oregioni, Giulia Mastroianni, Sara B-M. Whittaker, Geoff Kelly, Christian D. Lorenz, Arianna Fornili, Nicholas P. Cianciotto, James A. Garnett
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Bacterial adhesion is a fundamental process which enables colonisation of niche environments and is key for infection. However, in Legionella pneumophila, the causative agent of Legionnaires’ disease, these processes are not well understoo
Externí odkaz:
https://doaj.org/article/dc482835699a4915aefeb24d5457763d
Autor:
Brandi L. Cobe, Supratim Dey, George Minasov, Nicole Inniss, Karla J. F. Satchell, Nicholas P. Cianciotto
Publikováno v:
mBio, Vol 15, Iss 7 (2024)
ABSTRACT Stenotrophomonas maltophilia expresses a type IV protein secretion system (T4SS) that promotes contact-dependent killing of other bacteria and does so partly by secreting the effector TfcB. Here, we report the structure of TfcB, comprising a
Externí odkaz:
https://doaj.org/article/f13e5ad2659c467c91ad0bbde944bfd9
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
S. maltophiliaS. maltophilia
Externí odkaz:
https://doaj.org/article/11076c3f347c4b37b2b99a1949cfd2b8
Autor:
Theo J. Portlock, Jessica Y. Tyson, Sarath C. Dantu, Saima Rehman, Richard C. White, Ian E. McIntire, Lee Sewell, Katherine Richardson, Rosie Shaw, Alessandro Pandini, Nicholas P. Cianciotto, James A. Garnett
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Legionella pneumophila is a Gram-negative bacterium that is able to replicate within a broad range of aquatic protozoan hosts. L. pneumophila is also an opportunistic human pathogen that can infect macrophages and epithelia in the lung and lead to Le
Externí odkaz:
https://doaj.org/article/80a9c622cdc743b4bd1fac2e9b093da5
Autor:
Richard C. White, Felizza F. Gunderson, Jessica Y. Tyson, Katherine H. Richardson, Theo J. Portlock, James A. Garnett, Nicholas P. Cianciotto
Publikováno v:
mBio, Vol 9, Iss 2 (2018)
ABSTRACT Legionella pneumophila genes encoding LapA, LapB, and PlaC were identified as the most highly upregulated type II secretion (T2S) genes during infection of Acanthamoeba castellanii, although these genes had been considered dispensable on the
Externí odkaz:
https://doaj.org/article/d75fb773bfc340ef90dc4a00bcee3ceb
Autor:
Hilary K. Truchan, Harry D. Christman, Richard C. White, Nakisha S. Rutledge, Nicholas P. Cianciotto
Publikováno v:
mBio, Vol 8, Iss 3 (2017)
ABSTRACT Legionella pneumophila replicates in macrophages in a host-derived phagosome, termed the Legionella-containing vacuole (LCV). While the translocation of type IV secretion (T4S) effectors into the macrophage cytosol is well established, the l
Externí odkaz:
https://doaj.org/article/98adedf29ed347a8ace8ee383d6903ae
Publikováno v:
BioTechniques, Vol 27, Iss 3, Pp 508-511 (1999)
Pairs of primers flanking known miniTn10 transposon insertion sites were used to confirm the presence of the transposon in DNA isolated from Legionella pneumophila mutants. It was expected that the polymerase chain reaction products derived from the
Externí odkaz:
https://doaj.org/article/b99a9fea80a640d7af03b3c4153a6f8f
Autor:
Swarnava Chaudhuri, Benjamin N. Gantner, Richard D. Ye, Nicholas P. Cianciotto, Nancy E. Freitag
Publikováno v:
mBio, Vol 4, Iss 2 (2013)
ABSTRACT Environmental pathogens survive and replicate within the outside environment while maintaining the capacity to infect mammalian hosts. For some microorganisms, mammalian infection may be a relatively rare event. Understanding how environment
Externí odkaz:
https://doaj.org/article/6f3df39f694e4ad1b08be711e308672c
Publikováno v:
mBio, Vol 4, Iss 2 (2013)
ABSTRACT Recent studies have shown that the clustered regularly interspaced palindromic repeats (CRISPR) array and its associated (cas) genes can play a key role in bacterial immunity against phage and plasmids. Upon analysis of the Legionella pneumo
Externí odkaz:
https://doaj.org/article/b41b20d1f46242659759d27f35342e55
A summary of the research and investigation in the field; covers clinical and diagnostic information, epidemiology, basic microbiology and pathogenesis, and environmental detection and control.