Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Nicholas P. Casey"'
Autor:
Nadia Mensali, Hakan Köksal, Sandy Joaquina, Patrik Wernhoff, Nicholas P. Casey, Paola Romecin, Carla Panisello, René Rodriguez, Lene Vimeux, Asta Juzeniene, Marit R. Myhre, Anne Fåne, Carolina Castilla Ramírez, Solrun Melkorka Maggadottir, Adil Doganay Duru, Anna-Maria Georgoudaki, Iwona Grad, Andrés Daniel Maturana, Gustav Gaudernack, Gunnar Kvalheim, Angel M. Carcaboso, Enrique de Alava, Emmanuel Donnadieu, Øyvind S. Bruland, Pablo Menendez, Else Marit Inderberg, Sébastien Wälchli
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Osteosarcoma (OS) remains a dismal malignancy in children and young adults, with poor outcome for metastatic and recurrent disease. Immunotherapies in OS are not as promising as in some other cancer types due to intra-tumor heterogeneity and
Externí odkaz:
https://doaj.org/article/aeb35d7698f54300a9d32846913690b0
Autor:
Gunnar Kvalheim, Kristina Lindemann, Ben Davidson, Line Bjorge, Else Marit Inderberg, Sébastien Wälchli, Emmet McCormack, Katrin Kleinmanns, David J Warren, Erik Rokkones, Martine Lode, Nicholas P Casey, Christopher Forcados, Pascal F Gelebart, Sandy Joaquina, Emmanuelle Benard, Fatemeh Kaveh, Benjamin Caulier, Christiane Helgestad Gjerde, Elvira García de Jalón, Marit Renee Myhre
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 4 (2024)
Background Ovarian cancer (OC) is the leading cause of death from gynecologic malignancies in the Western world. Contributing factors include a high frequency of late-stage diagnosis, the development of chemoresistance, and the evasion of host immune
Externí odkaz:
https://doaj.org/article/162ad2ed429c4bd1b84eb0e5bfee44ad
Autor:
Christopher Forcados, Sandy Joaquina, Nicholas Paul Casey, Benjamin Caulier, Sébastien Wälchli
Publikováno v:
Cells, Vol 11, Iss 9, p 1454 (2022)
The manufacture of efficacious CAR T cells represents a major challenge in cellular therapy. An important aspect of their quality concerns energy production and consumption, known as metabolism. T cells tend to adopt diverse metabolic profiles depend
Externí odkaz:
https://doaj.org/article/3e5115d1a4954d548fda248c30a65dce
Resource-Area-Dependence Analysis: Inferring animal resource needs from home-range and mapping data.
Autor:
Robert E Kenward, Eduardo M Arraut, Peter A Robertson, Sean S Walls, Nicholas M Casey, Nicholas J Aebischer
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0206354 (2018)
An animal's home-range can be expected to encompass the resources it requires for surviving or reproducing. Thus, animals inhabiting a heterogeneous landscape, where resource patches vary in size, shape and distribution, will naturally have home-rang
Externí odkaz:
https://doaj.org/article/a6733549a64a4b78b02afa656f136fcf
Autor:
Nicholas Paul Casey, Hiroshi Fujiwara, Kazushi Tanimoto, Sachiko Okamoto, Junichi Mineno, Kiyotaka Kuzushima, Hiroshi Shiku, Masaki Yasukawa
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156896 (2016)
Aurora Kinase A is a cancer-associated protein normally involved in the regulation of mitosis. Being over-expressed in a range of cancers, it is a suitable target for cell-based immunotherapy. Gene transfer of T-cell receptor sequences cognisant of H
Externí odkaz:
https://doaj.org/article/3fa8366c1dd44b3fbd331fb5adbfa52a
Autor:
Lynne Selwood, Nicholas P. Casey
Publikováno v:
Cells, tissues, organs. 173(1)
The aim of the present study was to investigate the role of the marsupial shell coat in embryonic development because it may be a potential target for immunocontraceptive control of the brushtail possum. Conceptuses from 52 female possums were collec
Publikováno v:
Molecular reproduction and development. 62(2)
Little is known of the composition of the outer egg coats. We aimed to quantify secretion during embryonic development, identify precursor secreting cells and investigate protein composition. The study was based on 259 egg coats and 14 reproductive t
Autor:
Carole Beck, Nicholas Paul Casey, Irene Persiconi, Neda Nejati Moharrami, Adam Sike, Yixin Jin, Jon Amund Kyte
Publikováno v:
Biomedicines, Vol 11, Iss 2, p 459 (2023)
Therapy employing T cells modified with chimeric antigen receptors (CARs) is effective in hematological malignancies but not yet in solid cancers. CAR T cell activity in solid tumors is limited by immunosuppressive factors, including transforming gro
Externí odkaz:
https://doaj.org/article/cc6b3e2ca1914ce4b4c0035c66af2581