Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Nicholas P. Carbone"'
Autor:
Hui Zhang, Laura K. Simpson, Nicholas P. Carbone, Michael F. Hirshman, Pasquale Nigro, Maria Vamvini, Laurie J. Goodyear, Roeland J.W. Middelbeek
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107226- (2023)
Summary: Physical activity is important for type 2 diabetes treatment, yet the underlying mechanisms for these beneficial effects of exercise are not fully understood. Here, we investigated the effects of exercise training on biphasic β-cell insulin
Externí odkaz:
https://doaj.org/article/be98f540f398432e8b078db8ce1f2cd0
Autor:
Pasquale Nigro, Maria Vamvini, Jiekun Yang, Tiziana Caputo, Li-Lun Ho, Nicholas P. Carbone, Danae Papadopoulos, Royce Conlin, Jie He, Michael F. Hirshman, Joseph D. White, Jacques Robidoux, Robert C. Hickner, Søren Nielsen, Bente K. Pedersen, Manolis Kellis, Roeland J.W. Middelbeek, Laurie J. Goodyear
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112392- (2023)
Summary: Inguinal white adipose tissue (iWAT) is essential for the beneficial effects of exercise training on metabolic health. The underlying mechanisms for these effects are not fully understood, and here, we test the hypothesis that exercise train
Externí odkaz:
https://doaj.org/article/577f9f4134734bcd932687cedaaa5648
Autor:
Pasquale Nigro, Maria Vamvini, Jiekun Yang, Tiziana Caputo, Li-Lun Ho, Danae Papadopoulos, Nicholas P. Carbone, Royce Conlin, Jie He, Michael F. Hirshman, Joseph D. White, Jacques Robidoux, Robert C. Hickner, Søren Nielsen, Bente K. Pedersen, Manolis Kellis, Roeland J. W. Middelbeek, Laurie J. Goodyear
Inguinal white adipose tissue (iWAT) is essential for the beneficial effects of exercise training on metabolic health. Extracellular matrix (ECM) composition, innervation, and vascularization are all important regulators of iWAT function, yet whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf8a07c73cd0abfe9efd1e2e129f1035
https://doi.org/10.1101/2022.08.09.503375
https://doi.org/10.1101/2022.08.09.503375
Publikováno v:
Diabetes. 71
Type 2 diabetes (T2D) is associated with β-cell dysfunction. Although exercise is considered beneficial in T2D, the effects of moderate intensity endurance exercise training on β-cell function in humans with T2D are not known. GWAS uncovered Ras-Re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a5787ac0dbbff9b22a0d6baec61c450
https://doi.org/10.2337/db22-244-or
https://doi.org/10.2337/db22-244-or
Autor:
Jiekun Yang, Maria Vamvini, Pasquale Nigro, Li-Lun Ho, Kyriakitsa Galani, Marcus Alvarez, Yosuke Tanigawa, Ashley Renfro, Nicholas P. Carbone, Markku Laakso, Leandro Z. Agudelo, Päivi Pajukanta, Michael F. Hirshman, Roeland J.W. Middelbeek, Kevin Grove, Laurie J. Goodyear, Manolis Kellis
Publikováno v:
Cell Metabolism. 34:1578-1593.e6
Exercise training is critical for the prevention and treatment of obesity, but its underlying mechanisms remain incompletely understood given the challenge of profiling heterogeneous effects across multiple tissues and cell types. Here, we address th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea0772338f5a7040c260366e52d957b4
https://doi.org/10.1016/j.cmet.2022.09.004
https://doi.org/10.1016/j.cmet.2022.09.004