Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Nicholas P Wayham"'
Autor:
Nicholas P Wayham, Ariel R Niedecken, Jan Fredrik Simons, Yao Y Chiang, Angélica V Medina-Cucurella, Rena A Mizrahi, Ellen K Wagner, Ashley Gras, Ilana Segal, Peyton Witte, Alexis Enstrom, Aristea Bountouvas, Sabrina M Nelson, Tess Weinberger, David Tan, Michael A Asensio, Alagu Subramanian, Yoong Wearn Lim, Adam S Adler, Sheila M Keating
Publikováno v:
The Journal of Infectious Diseases.
Emerging variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) possess mutations that prevent antibody therapeutics from maintaining antiviral binding and neutralizing efficacy. Monoclonal antibodies (mAbs) shown to neutralize Wuha
Autor:
Erica L Stone, Kyle P Carter, Ellen K Wagner, Michael A Asensio, Emily Benzie, Yao Yuan Chiang, Garry L Coles, Chelsea Edgar, Bishal K Gautam, Ashley Gras, Jackson Leong, Renee Leong, Vishal A Manickam, Rena A Mizrahi, Ariel R Niedecken, Jasmeen Saini, Savreet K Sandhu, Jan Fredrick Simons, Kacy Stadtmiller, Brendan Tinsley, LaRee Tracy, Nicholas P Wayham, Yoong Wearn Lim, Adam S Adler, David S Johnson
Publikováno v:
Cancer Immunology Research. 10:A32-A32
Anti-CTLA-4 antibodies such as ipilimumab were among the first immuno-oncology agents to show significantly improved outcomes for patients. However, existing anti-CTLA-4 therapies fail to induce a response in a majority of patients and can induce sev