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pro vyhledávání: '"Nicholas P Ruppe"'
Publikováno v:
PLoS Genetics, Vol 16, Iss 2, p e1008608 (2020)
DNA double-strand breaks (DSBs) are toxic forms of DNA damage that must be repaired to maintain genome integrity. Telomerase can act upon a DSB to create a de novo telomere, a process that interferes with normal repair and creates terminal deletions.
Externí odkaz:
https://doaj.org/article/f7c7607b01844026a0659c2e56e471f4
Interaction of yeast Rad51 and Rad52 relieves Rad52-mediated inhibition of de novo telomere addition
Publikováno v:
PLoS Genetics, Vol 16, Iss 2, p e1008608 (2020)
PLoS Genetics
PLoS Genetics
DNA double-strand breaks (DSBs) are toxic forms of DNA damage that must be repaired to maintain genome integrity. Telomerase can act upon a DSB to create a de novo telomere, a process that interferes with normal repair and creates terminal deletions.