Zobrazeno 1 - 10
of 321 146
pro vyhledávání: '"Nicholas P"'
Autor:
Joel Tarning, Borimas Hanboonkunupakarn, Richard M. Hoglund, Kesinee Chotivanich, Mavuto Mukaka, Sasithon Pukrittayakamee, Nicholas P. J. Day, Nicholas J. White, Arjen M. Dondorp, Podjanee Jittamala
Publikováno v:
Malaria Journal, Vol 23, Iss 1, Pp 1-12 (2024)
Abstract Background Parenteral artesunate is the first-line therapy for severe malaria. Artesunate, in its current formulation, must be prepared immediately before administration by first dissolving in sodium bicarbonate solution and then diluting in
Externí odkaz:
https://doaj.org/article/32dcc3ae17bc4758901d806889a6ad88
Autor:
Adarsh Subbaswamy, Berkman Sahiner, Nicholas Petrick, Vinay Pai, Roy Adams, Matthew C. Diamond, Suchi Saria
Publikováno v:
npj Digital Medicine, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract A fundamental goal of evaluating the performance of a clinical model is to ensure it performs well across a diverse intended patient population. A primary challenge is that the data used in model development and testing often consist of many
Externí odkaz:
https://doaj.org/article/0dbaf911a51241f4974a46bfb135b97b
Autor:
XinYue Wang, William J. Jowsey, Chen-Yi Cheung, Caitlan J. Smart, Hannah R. Klaus, Noon EJ Seeto, Natalie JE Waller, Michael T. Chrisp, Amanda L. Peterson, Boatema Ofori-Anyinam, Emily Strong, Brunda Nijagal, Nicholas P. West, Jason H. Yang, Peter C. Fineran, Gregory M. Cook, Simon A. Jackson, Matthew B. McNeil
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Drug-resistant strains of Mycobacterium tuberculosis are a major global health problem. Resistance to the front-line antibiotic isoniazid is often associated with mutations in the katG-encoded bifunctional catalase-peroxidase. We hypothesise
Externí odkaz:
https://doaj.org/article/138d2c76fe9b40538e5e763113a839ee
Autor:
Daniel C. Scott, Sagar Chittori, Nicholas Purser, Moeko T. King, Samuel A. Maiwald, Kelly Churion, Amanda Nourse, Chan Lee, Joao A. Paulo, Darcie J. Miller, Stephen J. Elledge, J. Wade Harper, Gary Kleiger, Brenda A. Schulman
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Specificity of the ubiquitin-proteasome system depends on E3 ligase-substrate interactions. Many such pairings depend on E3 ligases binding to peptide-like sequences - termed N- or C-degrons - at the termini of substrates. However, our knowl
Externí odkaz:
https://doaj.org/article/1085cb553def4be2ba1ef9f68687d295
Publikováno v:
Radiology Case Reports, Vol 19, Iss 11, Pp 5271-5275 (2024)
This case report describes the imaging findings of an older-aged male presenting with infectious respiratory symptoms. Evaluation with routine contrast-enhanced CT of the chest demonstrated pulmonary artery filling defects initially treated as a pulm
Externí odkaz:
https://doaj.org/article/56196be85bbd47efb6b7d40f1fc7ae69
Autor:
Stefanie Lerche, Isabel Wurster, Enza Maria Valente, Micol Avenali, Daniela Samaniego, Marta Martínez-Vicente, Jorge Hernández-Vara, Ariadna Laguna, Andrea Sturchio, Per Svenningsson, Nicholas P. France, Carrolee Barlow, Sethu Sankaranarayanan, Kathrin Brockmann
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-6 (2024)
Abstract Variants in GBA1 result in dysregulated sphingolipids. We investigated five CSF d18:1 sphingolipid species in a longitudinal multicenter cohort comprising people with Parkinson’s Disease and Dementia with Lewy bodies with and without GBA1
Externí odkaz:
https://doaj.org/article/0432f15037794f51a76f397dcdb3ce10
Publikováno v:
BMC Health Services Research, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Background In Australia, lived experience peer support workforces are expanding making it one of the fastest growing emerging disciplines in transdisciplinary mental health settings. This article provides insight for organisations on the con
Externí odkaz:
https://doaj.org/article/9d64e4f2235b472aa4af4e85b6433565
Autor:
Jenna Kefeli, Jacob Berkowitz, Jose M. Acitores Cortina, Kevin K. Tsang, Nicholas P. Tatonetti
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-7 (2024)
Abstract Cancer staging is an essential clinical attribute informing patient prognosis and clinical trial eligibility. However, it is not routinely recorded in structured electronic health records. Here, we present BB-TEN: Big Bird – TNM staging Ex
Externí odkaz:
https://doaj.org/article/375869de715546538fec10b70e5b6fee
Radiopaque FeMnN-Mo composite drawn filled tubing wires for braided absorbable neurovascular devices
Autor:
Adam J. Griebel, Petra Maier, Henry Summers, Benjamin Clausius, Isabella Kanasty, Weilue He, Nicholas Peterson, Carolyn Czerniak, Alexander A. Oliver, David F. Kallmes, Ramanathan Kadirvel, Jeremy E. Schaffer, Roger J. Guillory, II
Publikováno v:
Bioactive Materials, Vol 40, Iss , Pp 74-87 (2024)
Flow diverter devices are small stents used to divert blood flow away from aneurysms in the brain, stagnating flow and inducing intra-aneurysmal thrombosis which in time will prevent aneurysm rupture. Current devices are formed from thin (∼25 μm)
Externí odkaz:
https://doaj.org/article/aa49ed5649e54d62bb578d85ba7c5235
Publikováno v:
Journal of Hand Surgery Global Online, Vol 6, Iss 5, Pp 694-699 (2024)
Reconstruction of peripheral mixed motor/sensory nerves using autografts has remained the gold standard. Inconsistent and nonphysiologic results across nerve allograft studies, including successful and failed motor reinnervation, have limited the cur
Externí odkaz:
https://doaj.org/article/2dd4bf3f5bf145d08882e53d292bbecb