Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Nicholas Nagykery"'
Autor:
Lindsey M. Vansandt, Marie-Charlotte Meinsohn, Philippe Godin, Nicholas Nagykery, Natalie Sicher, Motohiro Kano, Aki Kashiwagi, Maeva Chauvin, Hatice D. Saatcioglu, Julie L. Barnes, Amy G. Miller, Amy K. Thompson, Helen L. Bateman, Elizabeth M. Donelan, Raquel González, Jackie Newsom, Guangping Gao, Patricia K. Donahoe, Dan Wang, William F. Swanson, David Pépin
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract Eighty percent of the estimated 600 million domestic cats in the world are free-roaming. These cats typically experience suboptimal welfare and inflict high levels of predation on wildlife. Additionally, euthanasia of healthy animals in over
Externí odkaz:
https://doaj.org/article/190d36565fa84c9e9cbd0f745505260e
Autor:
Hatice Duygu Saatcioglu, Motohiro Kano, Heiko Horn, Lihua Zhang, Wesley Samore, Nicholas Nagykery, Marie-Charlotte Meinsohn, Minsuk Hyun, Rana Suliman, Joy Poulo, Jennifer Hsu, Caitlin Sacha, Dan Wang, Guangping Gao, Kasper Lage, Esther Oliva, Mary E Morris Sabatini, Patricia K Donahoe, David Pépin
Publikováno v:
eLife, Vol 8 (2019)
The Mullerian ducts are the anlagen of the female reproductive tract, which regress in the male fetus in response to MIS. This process is driven by subluminal mesenchymal cells expressing Misr2, which trigger the regression of the adjacent Mullerian
Externí odkaz:
https://doaj.org/article/dc7ad2dba29a41beb65fb95ef1219743
Autor:
Yi Li, Lina Wei, Marie-Charlotte Meinsohn, Rana Suliman, Maeva Chauvin, Jim Berstler, Kate Hartland, Mark M. Jensen, Natalie A. Sicher, Nicholas Nagykery, Patricia K. Donahoe, David Pepin
Publikováno v:
Proceedings of the National Academy of Sciences. 119
We identified the anti-Mullerian hormone (also known as Müllerian inhibiting substance or MIS) as an inhibitory hormone that induces long-term contraception in mammals. The type II receptor to this hormone, AMHR2 (also known as MISR2), represents a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f525aa6d19587dadd09ff6ef2d6b3e0
https://doi.org/10.1073/pnas.2122512119
https://doi.org/10.1073/pnas.2122512119
Autor:
Kaitlin N. Hart, Thomas B. Thompson, William A. Stocker, Craig A. Harrison, David Pépin, Nicholas Nagykery, Patricia K. Donahoe, Kelly L. Walton
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Anti-Müllerian hormone (AMH) plays a crucial role in male sex differentiation and female reproductive development. As such, AMH is widely used as a biomarker for measuring a woman’s fertility, estimating onset of menopause, and has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e345a124a4e88eb7d8c097c5fb9066d0
https://pubmed.ncbi.nlm.nih.gov/34155118
https://pubmed.ncbi.nlm.nih.gov/34155118
Autor:
David Pépin, LiHua Zhang, Mary E. Sabatini, Jennifer Y. Hsu, Patricia K. Donahoe, Motohiro Kano, Nicholas Nagykery, Hatice D. Saatcioglu
Publikováno v:
Journal of the Endocrine Society
Müllerian-inhibiting substance (MIS), also known as anti-Müllerian hormone, is thought to be a negative regulator of primordial follicle activation. We have previously reported that treatment with exogenous MIS can induce complete ovarian suppressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ea5a7f039e6315772dac822bf7ac570
https://doi.org/10.1210/js.2019-00190
https://doi.org/10.1210/js.2019-00190
Autor:
Aki Kashiwagi, David Pépin, Ngoc Minh Phuong Nguyen, Maeva Chauvin, Guangping Gao, Esther Oliva, Heiko Horn, Motohiro Kano, Nicholas Nagykery, Wesley R Samore, Mary E. Morris, Marie-Charlotte Meinsohn, Patricia K. Donahoe, Dan Wang, Lina Wei, Hatice D. Saatcioglu, Yi Li
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance This study improves our understanding of the role of Müllerian inhibiting substance (MIS/AMH) in antagonizing primordial follicle activation. By applying scRNA-seq methods to neonatal mouse ovaries, we revealed transcriptional signature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5110d39f4be60cd0b3fa7f95278e9705
https://pubmed.ncbi.nlm.nih.gov/33980714
https://pubmed.ncbi.nlm.nih.gov/33980714
Autor:
LiHua Zhang, Heather R. Keys, Hatice D. Saatcioglu, Nicholas Nagykery, David M. Sabatini, Yi Li, David Pépin, Raghav Mohan, Nobuhiro Takahashi, Patricia K. Donahoe
Publikováno v:
Clinical Cancer Research. 26:A63-A63
Background: Epithelial ovarian cancers are the fifth leading cause of cancer-related deaths in American women, with a five-year overall survival rate for patients diagnosed at advanced stages of less than 30%. High-grade serous ovarian cancers (HGSOC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a77107fe71723e560159022f50f121c
https://doi.org/10.1158/1557-3265.ovca19-a63
https://doi.org/10.1158/1557-3265.ovca19-a63
Autor:
Heiko Horn, Minsuk Hyun, Marie-Charlotte Meinsohn, Patricia K. Donahoe, Kasper Lage, David Pépin, Caitlin R. Sacha, Wesley R Samore, Motohiro Kano, Nicholas Nagykery, Jennifer Y. Hsu, Joy Poulo, Dan Wang, Guangping Gao, Esther Oliva, LiHua Zhang, Mary E. Sabatini, Rana Suliman, Hatice D. Saatcioglu
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
The Mullerian ducts are the anlagen of the female reproductive tract, which regress in the male fetus in response to MIS. This process is driven by subluminal mesenchymal cells expressing Misr2, which trigger the regression of the adjacent Mullerian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e71d1e218df3f771e916f1f0c13a4dfc
https://doi.org/10.7554/elife.46349
https://doi.org/10.7554/elife.46349
Autor:
David Pépin, Jennifer Y. Hsu, Joy Poulo, Kasper Lage, Wesley R Samore, Esther Oliva, Minsuk Hyun, Guangping Gao, Dan Wang, LiHua Zhang, Mary E. Sabatini, Heiko Horn, Hatice D. Saatcioglu, Motohiro Kano, Marie-Charlotte Meinsohn, Rana Suliman, Nicholas Nagykery, Patricia K. Donahoe, Caitlin R. Sacha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::47dcb41419be23e03655880fc412403c
https://doi.org/10.7554/elife.46349.036
https://doi.org/10.7554/elife.46349.036
Autor:
Raghav Mohan, Motohiro Kano, Hatice D. Saatcioglu, Nicholas Nagykery, David Pepin, Nobuhiro Takahashi, Patricia K. Donahoe, Joy Poulo, LiHua Zhang
Publikováno v:
Clinical Cancer Research. 25:AP29-AP29
Mullerian inhibiting substance (MIS) has been shown to inhibit the growth of a stem-like population of ovarian cancer cells both in vivo and in vitro. We have previously shown that its receptor, MISRII, is expressed in a majority of ovarian serous ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ed0f5bfbdb572ca62836e6081dcec10
https://doi.org/10.1158/1557-3265.ovcasymp18-ap29
https://doi.org/10.1158/1557-3265.ovcasymp18-ap29