Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nicholas N. Shaw"'
Publikováno v:
Journal of Chemical Education. 98:167-174
Working with undergraduates in an organic synthesis research laboratory presents a unique set of challenges. An undergraduate research program must be designed to focus on teaching students to “thi...
Publikováno v:
Aminoglycoside Antibiotics
Autor:
Nicholas N. Shaw, Arthur Chlebowski, Nicholas G. Tolman, Margaret Ryan, Alexander D. M. Kokini, Jeffrey K. Marchant, Nelson F. Freeburg, Simon W. M. John, Krishnakumar Kizhatil
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose The molecular mechanisms controlling aqueous humor (AQH) outflow and IOP need much further definition. The mouse is a powerful system for characterizing the mechanistic basis of AQH outflow. To enhance outflow studies in mice, we developed a
Publikováno v:
Bioorganicmedicinal chemistry letters. 18(14)
A novel neomycin–methidium conjugate was synthesized. The covalent linkage of the aminoglycoside to an intercalator, a derivative of ethidium bromide, results in a new conjugate capable of selective recognition of the DNA:RNA hybrid duplex. Spectro
Autor:
Dev P. Arya, Nicholas N. Shaw
Publikováno v:
Biochimie. 90(7)
Targeting nucleic acids using small molecules routinely uses the end products in the conversion pathway of "DNA to RNA, RNA to protein". However, the intermediate processes in this path have not always been targeted. The DNA-RNA interaction, specific
Autor:
David Soulsby, Laura J. Anna, Anton S. Wallner, Janice Alexander, Jason Ashmore, Anthony Baker, Scott Chadwick, Laura Medhurst, Farzana Shahnaz, Nirmala Ramnarine, Giordano Paniconi, Judith C. Amburgey-Peters, Paul A. Bonvallet, Connie Gabel, Rosemarie Walker, Julia P. Baker, S. M. Dimick Gray, Sherri C. Young, Kyle T. Smith, James W. DeBlasio, Christian S. Hamann, Vernon R. Miller, Christopher R. Butler, Allen M. Schoffstall, Richard K. Shoemaker