Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Nicholas N. Dang"'
Isolation of L I domain mutants mediating firm cell adhesion using a novel flow-based sorting method
Autor:
Gregory P. Robbins, Daniel A. Hammer, Ranganath Parthasarathy, Eric T. Boder, Lauren R. Pepper, Nicholas N. Dang
Publikováno v:
Protein Engineering Design and Selection. 26:515-521
The inserted (I) domain of αLβ2 integrin (LFA-1) contains the entire binding site of the molecule. It mediates both rolling and firm adhesion of leukocytes at sites of inflammation depending on the activation state of the integrin. The affinity cha
Autor:
Lillian Chau, Qin Zhang, Boris Reizis, Yongwon Choi, Kyle Bittinger, Frederic D. Bushman, Daehee Han, Gary D. Wu, Matthew C. Walsh, Paloma Cejas, Youngmi Kim, Jihyun Kim, Hao Shen, Anthony L. DeFranco, Laurence A. Turka, Nicholas N. Dang, Laetitia Charrier-Hisamuddin
Publikováno v:
Immunity, vol 38, iss 6
The intracellular signaling molecule TRAF6 is critical for Toll-like receptor (TLR)-mediated activation of dendritic cells (DCs). We now report that DC-specific deletion of TRAF6 (TRAF6ΔDC) resulted, unexpectedly, in loss of mucosal tolerance, chara