Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Nicholas N Jarjour"'
Autor:
Anshu P Gounder, Christine C Yokoyama, Nicholas N Jarjour, Traci L Bricker, Brian T Edelson, Adrianus C M Boon
Publikováno v:
PLoS Pathogens, Vol 14, Iss 4, p e1007001 (2018)
Pro-inflammatory cytokinemia is a hallmark of highly pathogenic H5N1 influenza virus (IAV) disease yet little is known about the role of host proteins in modulating a pathogenic innate immune response. The host Interferon Induced Protein 35 (Ifi35) h
Externí odkaz:
https://doaj.org/article/fbf7620cce494db7af4bb838d1c65d9c
Autor:
Matthew M. Gubin, Brian T. Edelson, Ken Chen, Reshma Taneja, Josué E. Pineda, Anna M. Highsmith, Jeffrey P. Ward, Charmelle D. Williams, Ekaterina Esaulova, Sunita Keshari, Nicholas N. Jarjour, Qi Miao, Alexander S. Shavkunov, Avery J. Salmon
Immune checkpoint therapy (ICT) using antibody blockade of programmed cell death protein 1 (PD-1) or cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) can provoke T cell–dependent antitumor activity that generates durable clinical responses in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76db012299fcae59fe721ea91357eaff
https://doi.org/10.1158/2326-6066.c.6550554.v1
https://doi.org/10.1158/2326-6066.c.6550554.v1
Autor:
Matthew M. Gubin, Brian T. Edelson, Ken Chen, Reshma Taneja, Josué E. Pineda, Anna M. Highsmith, Jeffrey P. Ward, Charmelle D. Williams, Ekaterina Esaulova, Sunita Keshari, Nicholas N. Jarjour, Qi Miao, Alexander S. Shavkunov, Avery J. Salmon
Supplementary Figure from BHLHE40 Regulates the T-Cell Effector Function Required for Tumor Microenvironment Remodeling and Immune Checkpoint Therapy Efficacy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2eab028610fe4cfde3108c6638150e4c
https://doi.org/10.1158/2326-6066.22544160
https://doi.org/10.1158/2326-6066.22544160
Autor:
Nicholas N. Jarjour, Kelsey M. Wanhainen, Changwei Peng, Noah V. Gavil, Nicholas J. Maurice, Henrique Borges da Silva, Ryan J. Martinez, Talia S. Dalzell, Matthew A. Huggins, David Masopust, Sara E. Hamilton, Stephen C. Jameson
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Interleukin-15 (IL-15) is often considered a central regulator of memory CD8 + T cells, based primarily on studies of recirculating subsets. However, recent work identified IL-15–independent CD8 + T cell memory populations, including tissue-residen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd48cc0d24205f7b0ff03bb1eb4a5acd
https://doi.org/10.1073/pnas.2209021119
https://doi.org/10.1073/pnas.2209021119
Autor:
Chin-Wen Lai, Prachi Bagadia, Derek A. G. Barisas, Nicholas N. Jarjour, Rachel Wong, Takahiro Ohara, Brian D. Muegge, Qiuhe Lu, Shanshan Xiong, Brian T. Edelson, Kenneth M. Murphy, Thaddeus S. Stappenbeck
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 209(4)
The local microenvironment shapes macrophage differentiation in each tissue. We hypothesized that in the peritoneum, local factors in addition to retinoic acid can support GATA6-driven differentiation and function of peritoneal large cavity macrophag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::776df263759dc4df34d47f65cd554f3a
https://pubmed.ncbi.nlm.nih.gov/35868637
https://pubmed.ncbi.nlm.nih.gov/35868637
Publikováno v:
Trends Immunol
The basic helix-loop-helix transcription factor Bhlhe40 is emerging as a key regulator of immunity during infection, autoimmunity, and inflammatory conditions. We describe roles of Bhlhe40 in the circulating and tissue-resident arms of the immune sys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b792034c79ffbe0d39f4b07f79ec644
https://doi.org/10.1016/j.it.2020.09.002
https://doi.org/10.1016/j.it.2020.09.002
Autor:
Ming Zhao, Kaiqun Ren, Xiwen Xiong, Yue Xin, Yujie Zou, Jason C. Maynard, Angela Kim, Alexander P. Battist, Navya Koneripalli, Yusu Wang, Qianyue Chen, Ruyue Xin, Chenyan Yang, Rong Huang, Jiahui Yu, Zan Huang, Zengdi Zhang, Haiguang Wang, Daoyuan Wang, Yihui Xiao, Oscar C. Salgado, Nicholas N. Jarjour, Kristin A. Hogquist, Xavier S. Revelo, Alma L. Burlingame, Xiang Gao, Jakob von Moltke, Zhaoyu Lin, Hai-Bin Ruan
Publikováno v:
Immunity
The epithelium is an integral component of mucosal barrier and host immunity. Following helminth infection, the intestinal epithelial cells secrete "alarmin" cytokines, such as interleukin-25 (IL-25) and IL-33, to initiate the type 2 immune responses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a55872d8119a1575f1fd3cc2f388c52
https://pubmed.ncbi.nlm.nih.gov/35830826
https://pubmed.ncbi.nlm.nih.gov/35830826
Autor:
Reshma Taneja, Brian T. Edelson, Elizabeth A. Schwarzkopf, Joseph F. Urban, Tara R. Bradstreet, Irina Shchukina, Gwendalyn J. Randolph, Maxim N. Artyomov, Thaddeus S. Stappenbeck, Chih-Chung Lin, Stanley Ching-Cheng Huang, Melissa E. Cook, Nicholas N. Jarjour, Chin-Wen Lai
Publikováno v:
Nature immunology
Most tissue-resident macrophage populations develop during embryogenesis, self-renew in the steady state and expand during type 2 immunity. Whether shared mechanisms regulate the proliferation of macrophages in homeostasis and disease is unclear. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3097f32cd93ad2cf389e6d13b670bbd0
https://doi.org/10.1038/s41590-019-0382-5
https://doi.org/10.1038/s41590-019-0382-5
Autor:
Bernd H. Zinselmeyer, Brian Saunders, Audrey C. A. Cleuren, George J. Broze, Brian T. Edelson, Rafael S. Czepielewski, Steven P. Grover, Gwendalyn J. Randolph, Nicholas N. Jarjour, Emma C. Erlich, Nigel Mackman, Nan Zhang, Ekaterina Esaulova
Publikováno v:
The Journal of Experimental Medicine
Clotting factors made by resident peritoneal macrophages promote microbial trapping in fluid microenvironments where microbes might otherwise escape.
Macrophages resident in different organs express distinct genes, but understanding how this div
Macrophages resident in different organs express distinct genes, but understanding how this div
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c551c2a15e05b12791421438d3a7b24
http://europepmc.org/articles/PMC6547866
http://europepmc.org/articles/PMC6547866
Autor:
Avery J. Salmon, Alexander S. Shavkunov, Qi Miao, Nicholas N. Jarjour, Sunita Keshari, Ekaterina Esaulova, Charmelle D. Williams, Jeffrey P. Ward, Anna M. Highsmith, Josué E. Pineda, Reshma Taneja, Ken Chen, Brian T. Edelson, Matthew M. Gubin
Publikováno v:
Cancer Immunol Res
Immune checkpoint therapy (ICT) using antibody blockade of programmed cell death protein 1 (PD-1) or cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) can provoke T cell–dependent antitumor activity that generates durable clinical responses in s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49b0fa56584fc7bcc9409ca4ed40d1db
https://pubmed.ncbi.nlm.nih.gov/35181783
https://pubmed.ncbi.nlm.nih.gov/35181783