Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Nicholas Mourikis"'
Autor:
Michele Petruzzelli, Miriam Ferrer, Martijn J. Schuijs, Sam O. Kleeman, Nicholas Mourikis, Zoe Hall, David Perera, Shwethaa Raghunathan, Michele Vacca, Edoardo Gaude, Michael J. Lukey, Duncan I. Jodrell, Christian Frezza, Erwin F. Wagner, Ashok R. Venkitaraman, Timotheus Y. F. Halim, Tobias Janowitz
Publikováno v:
Cancers, Vol 14, Iss 4, p 963 (2022)
An elevated neutrophil–lymphocyte ratio negatively predicts the outcome of patients with cancer and is associated with cachexia, the terminal wasting syndrome. Here, using murine model systems of colorectal and pancreatic cancer we show that neutro
Externí odkaz:
https://doaj.org/article/7f4567f3741343deb91668ec9f55d942
Autor:
Miriam Ferrer, Nicholas Mourikis, Emma E. Davidson, Sam O. Kleeman, Marta Zaccaria, Jill Habel, Rachel Rubino, Thomas R. Flint, Claire M. Connell, Michael Lukey, Eileen P. White, Anthony P. Coll, Ashok R. Venkitaraman, Tobias Janowitz
Publikováno v:
bioRxiv
The dependency of cancer cells on glucose can be targeted with high-fat low-carbohydrate ketogenic diet (KD). However, hepatic ketogenesis is suppressed in IL-6 producing cancers, which prevents the utilization of this nutrient source as energy for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95f8cbe42ba74f721a9de0d3f28804df
https://europepmc.org/articles/PMC9949105/
https://europepmc.org/articles/PMC9949105/
Autor:
Miriam Ferrer, Nicholas Mourikis, Emma E. Davidson, Sam O. Kleeman, Marta Zaccaria, Jill Habel, Rachel Rubino, Thomas R. Flint, Claire M. Connell, Michael J. Lukey, Eileen P. White, Anthony P. Coll, Ashok R. Venkitaraman, Tobias Janowitz
Publikováno v:
Cancer Research. 83:1162-1162
The dependency of cancer cells on glucose can be targeted with high-fat low-carbohydrate ketogenic diet (KD). However, hepatic ketogenesis is suppressed in IL-6 producing cancers, which prevents the utilization of this nutrient source as energy for t
Autor:
Christina M Brennan, Sandeep Nadella, Xiang Zhao, Richard J Dima, Nicole Jordan-Martin, Breanna R Demestichas, Sam O Kleeman, Miriam Ferrer, Eva Carlotta von Gablenz, Nicholas Mourikis, Michael E Rubin, Harsha Adnani, Hassal Lee, Taehoon Ha, Soma Prum, Cheryl B Schleicher, Sharon S Fox, Michael G Ryan, Christina Pili, Gary Goldberg, James M Crawford, Sara Goodwin, Xiaoyue Zhang, Jonathan B Preall, Ana S H Costa, Joseph Conigliaro, Joseph R Masci, Jie Yang, David A Tuveson, Kevin J Tracey, Tobias Janowitz
Publikováno v:
Gut. 71(5)
ObjectiveWe assessed whether famotidine improved inflammation and symptomatic recovery in outpatients with mild to moderate COVID-19.DesignRandomised, double-blind, placebo-controlled, fully remote, phase 2 clinical trial (NCT04724720) enrolling symp
Autor:
Sam O. Kleeman, Breanna Demestichas, Nicholas Mourikis, Dominik Loiero, Miriam Ferrer, Sean Bankier, Yosef J.R.A. Riazat-Kesh, Hassal Lee, Dimitrios Chantzichristos, Claire Regan, Jonathan Preall, Sarthak Sinha, Nicole Rosin, Bryan Yipp, Luiz G.N. de Almeida, Jeff Biernaskie, Antoine Dufour, Pinkus Tober-Lau, Arno Ruusalepp, Johan L. M. Bjorkegren, Markus Ralser, Florian Kurth, Vadim Demechev, Todd Heywood, Qing Gao, Gudmundur Johannsson, Viktor H. Koelzer, Brian R. Walker, Hannah V. Meyer, Tobias Janowitz
The secreted protein Cystatin C (CyC) is a cysteine protease inhibitor of incompletely characterized biomedical function, used clinically for estimation of glomerular filtration rate. Plasma CyC is elevated in many patients, especially when they rece
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b15f807a2bceeb5faa7785099921576
https://doi.org/10.1101/2021.08.17.21261668
https://doi.org/10.1101/2021.08.17.21261668
Autor:
Michele Petruzzelli, Miriam Ferrer, Martijn J. Schuijs, Sam O. Kleeman, Nicholas Mourikis, Zoe Hall, David Perera, Shwethaa Raghunathan, Michele Vacca, Edoardo Gaude, Michael J. Lukey, Duncan I. Jodrell, Christian Frezza, Erwin F. Wagner, Ashok R. Venkitaraman, Timotheus Y. F. Halim, Tobias Janowitz
Publikováno v:
Cancers; Volume 14; Issue 4; Pages: 963
An elevated neutrophil–lymphocyte ratio negatively predicts the outcome of patients with cancer and is associated with cachexia, the terminal wasting syndrome. Here, using murine model systems of colorectal and pancreatic cancer we show that neutro