Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Nicholas Mitsios"'
Autor:
Okan Gultekin, Jordi Gonzalez-Molina, Elin Hardell, Lidia Moyano-Galceran, Nicholas Mitsios, Jan Mulder, Georgia Kokaraki, Anders Isaksson, Dhifaf Sarhan, Kaisa Lehti, Joseph W. Carlson
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-11 (2021)
Abstract Uterine sarcomas are rare but deadly malignancies without effective treatment. Immunotherapy is a promising new approach to treat these tumors but has shown heterogeneous effects in sarcoma patients. With the goal of identifying key factors
Externí odkaz:
https://doaj.org/article/eda4826495d543a98d261183c1886ac9
Autor:
Evelina Sjöstedt, Linn Fagerberg, Björn M Hallström, Anna Häggmark, Nicholas Mitsios, Peter Nilsson, Fredrik Pontén, Tomas Hökfelt, Mathias Uhlén, Jan Mulder
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130028 (2015)
The mammalian brain is a complex organ composed of many specialized cells, harboring sets of both common, widely distributed, as well as specialized and discretely localized proteins. Here we focus on the human brain, utilizing transcriptomics and pu
Externí odkaz:
https://doaj.org/article/616cf32f1faf4e85b52cdc1333da35d2
Autor:
Staffan Holmin, Jan Mulder, Fabian Arnberg, Emma Jussing, Thuy A Tran, Philip Little, Li Lu, Andreas Tue Ingemann Jensen, Nicholas Mitsios
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 41:617-629
PET hypoxia imaging can assess tissue viability in acute ischemic stroke (AIS). [18F]FMISO is an established tracer but requires substantial accumulation time, limiting its use in hyperacute AIS. [64Cu]CuATSM requires less accumulation time and has s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::563a2dec46527076f6cfbb787f165fa9
https://doi.org/10.1177/0271678x20923857
https://doi.org/10.1177/0271678x20923857
Autor:
Jan Mulder, Christopher J. Schmidt, Andrea Varrone, Christer Halldin, Balázs Gulyás, Ignacio Munoz-Sanjuan, Ladislav Mrzljak, Katarina Varnäs, Nicholas Mitsios, Marie Svedberg, Vahri Beaumont, Margaret M. Zaleska
Publikováno v:
Brain Research. 1711:140-145
Highly specific and sensitive biomarkers for pathologies related to dysfunctions in the basal ganglia circuit are of great value to assess therapeutic efficacy not only clinically to establish an early diagnosis, but also in terms of monitoring the e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a3664e55a5616ccc6b765cb33c90b48
https://doi.org/10.1016/j.brainres.2019.01.021
https://doi.org/10.1016/j.brainres.2019.01.021
Autor:
Pernilla Roswall, Jessica Svedlund, Shao Bo Jin, Ceren Mutgan, Hemming Johansson, Jonas Bergh, Jan Mulder, Janna Paulsson, Sarah Marie Wickberg, Arne Östman, Kristian Pietras, Derek C. Radisky, Artur Mezheyeuski, Fredrik Wärnberg, Mats Nilsson, Urban Lendahl, Per Hall, Carina Strell, Nicholas P. Tobin, Nicholas Mitsios
Publikováno v:
JNCI: Journal of the National Cancer Institute. 111:983-995
BackgroundA better definition of biomarkers and biological processes related to local recurrence and disease progression is highly warranted for ductal breast carcinoma in situ (DCIS). Stromal–epithelial interactions are likely of major importance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd075e261d4155a6ed2d9bb691f3ca29
https://doi.org/10.1093/jnci/djy234
https://doi.org/10.1093/jnci/djy234
Autor:
Dhifaf Sarhan, Jan Mulder, Okan Gultekin, Nicholas Mitsios, Lidia Moyano-Galceran, Joseph W. Carlson, Elin Hardell, Jordi Gonzalez-Molina, Georgia Kokaraki, Anders Isaksson, Kaisa Lehti
PurposeUterine sarcomas are rare but deadly malignancies without effective treatment. The goal of this study was to characterize and identify potential mechanisms underlying observed variations in the immune microenvironment of different sarcoma subt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a864862b9f44c6251fbda7c5551cd932
https://doi.org/10.1101/2021.03.26.437169
https://doi.org/10.1101/2021.03.26.437169
Autor:
Jan Mulder, Nicholas Mitsios, Jordi Gonzalez-Molina, Lidia Moyano-Galceran, Joseph W. Carlson, Kaisa Lehti, Dhifaf Sarhan, Georgia Kokaraki, Okan Gultekin, Anders Isaksson, Elin Hardell
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-11 (2021)
NPJ Precision Oncology
NPJ precision oncology
NPJ Precision Oncology
NPJ precision oncology
Uterine sarcomas are rare but deadly malignancies without effective treatment. Immunotherapy is a promising new approach to treat these tumors but has shown heterogeneous effects in sarcoma patients. With the goal of identifying key factors for impro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b6283059d68014f547d54efb63196f6
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-460086
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-460086
Autor:
Yutao Du, Jan Mulder, Ling Yang, Lin Lin, Wen Zhong, Evelina Sjöstedt, Kalle von Feilitzen, Adil Mardinoglu, Lars Bolund, Xun Xu, Zhanying Dong, Linn Fagerberg, Tomas Hökfelt, Jinrong Huang, Csaba Adori, Fredrik Edfors, Xin Liu, Mathias Uhlén, Jian Wang, Hui Jiang, Cheng Zhang, Cecilia Lindskog, Agnieszka Limiszewska, Feria Hikmet, Max J. Karlsson, Yonglun Luo, Huanming Yang, Fredrik Pontén, Per Oksvold, Nicholas Mitsios
Publikováno v:
Sjöstedt, E, Zhong, W, Fagerberg, L, Karlsson, M, Mitsios, N, Adori, C, Oksvold, P, Edfors, F, Limiszewska, A, Hikmet, F, Huang, J, Du, Y, Lin, L, Dong, Z, Yang, L, Liu, X, Jiang, H, Xu, X, Wang, J, Yang, H, Bolund, L, Mardinoglu, A, Zhang, C, von Feilitzen, K, Lindskog, C, Pontén, F, Luo, Y, Hökfelt, T, Uhlén, M & Mulder, J 2020, ' An atlas of the protein-coding genes in the human, pig, and mouse brain ', Science, vol. 367, no. 6482, 5947 . https://doi.org/10.1126/science.aay5947
Mapping the mammalian brain The diverse physiology of the brain is reflected in its complex organization at regional, cellular, and subcellular levels. Sjöstedt et al. combined data—both newly acquired and from other large-scale brain mapping proj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0d0410db4d15d17adb9e9594899a5d0
https://doi.org/10.1126/science.aay5947
https://doi.org/10.1126/science.aay5947
Autor:
Jan Mulder, Eva Lindholm Carlström, Mathias Uhlén, Nicholas Mitsios, Anna Månberg, David Just, Lars Feuk, Peter Nilsson, Grazyna Rajkowska, Craig A. Stockmeier, Janet L. Cunningham
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-12 (2020)
Translational Psychiatry
Translational Psychiatry
In recent years, studies have shown higher prevalence of autoantibodies in patients with schizophrenia compared to healthy individuals. This study applies an untargeted and a targeted affinity proteomics approach to explore and characterize the autoa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef48286d3993ef01518e389ee77e0a5b
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-428314
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-428314
Autor:
Daniel Andersson, Marcela Pekna, Jan Mulder, Roy Pekny, Nicholas Mitsios, Ulrika Wilhelmsson, Tibor Hortobágyi, Yolanda de Pablo, Milos Pekny, Anders Ståhlberg
Publikováno v:
Cerebral Cortex. 27:3360-3377
Microglia and astrocytes have been considered until now as cells with very distinct identities. Here, we assessed the heterogeneity within microglia/monocyte cell population in mouse hippocampus and determined their response to injury, by using singl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd4f5c46a6a6a42aefc3fedd07386791
https://doi.org/10.1093/cercor/bhx069
https://doi.org/10.1093/cercor/bhx069