Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Nicholas M. Tran"'
Autor:
Jin Li, Jongsu Choi, Xuesen Cheng, Justin Ma, Shahil Pema, Joshua R. Sanes, Graeme Mardon, Benjamin J. Frankfort, Nicholas M. Tran, Yumei Li, Rui Chen
Publikováno v:
iScience, Vol 27, Iss 6, Pp 109916- (2024)
Summary: Single-cell RNA sequencing (scRNA-seq) has advanced our understanding of cellular heterogeneity by characterizing cell types across tissues and species. While several mouse retinal scRNA-seq datasets exist, each dataset is either limited in
Externí odkaz:
https://doaj.org/article/65d6d83bef1f49cd8b7fecbf3affb4c8
Autor:
Inbal Benhar, Jiarui Ding, Wenjun Yan, Irene E. Whitney, Anne Jacobi, Malika Sud, Grace Burgin, Karthik Shekhar, Nicholas M. Tran, Chen Wang, Zhigang He, Joshua R. Sanes, Aviv Regev
Publikováno v:
Nature immunology, vol 24, iss 4
Non-neuronal cells are key to the complex cellular interplay that follows central nervous system insult. To understand this interplay, we generated a single-cell atlas of immune, glial and retinal pigment epithelial cells from adult mouse retina befo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d8a25e32c4f97c601714b4199c9b577
https://escholarship.org/uc/item/9zj7f36w
https://escholarship.org/uc/item/9zj7f36w
Autor:
Preethi Somasundaram, Madeline M. Farley, Melissa A. Rudy, David G. Stefanoff, Malay Shah, Puneetha Goli, Jenny Heo, Shufang Wang, Nicholas M. Tran, Trent A. Watkins
Publikováno v:
bioRxiv
Previously we showed that neurodegeneration initiated by axonal insults depends in part on the stress-responsive kinase Perk (Larhammar et al., 2017). Here we show that Perk acts primarily through Activating Transcription Factor-4 (Atf4) to stimulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29f4973c937ba61fb3452eb0cf50b0bc
https://doi.org/10.1101/2023.03.29.534798
https://doi.org/10.1101/2023.03.29.534798
Autor:
Anne Jacobi, Nicholas M. Tran
Publikováno v:
Methods in Molecular Biology ISBN: 9781071630112
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38a2fe1a497c845c7b99822e39c0e521
https://doi.org/10.1007/978-1-0716-3012-9_1
https://doi.org/10.1007/978-1-0716-3012-9_1
Autor:
Joshua R. Sanes, Wenjun Yan, Mallory A. Laboulaye, Irene E. Whitney, Nicholas M. Tran, Inbal Benhar
Publikováno v:
J Neurosci
Amacrine cells (ACs) are a diverse class of interneurons that modulate input from photoreceptors to retinal ganglion cells (RGCs), rendering each RGC type selectively sensitive to particular visual features, which are then relayed to the brain. While
Autor:
Anne Jacobi, Nicholas M. Tran, Wenjun Yan, Inbal Benhar, Feng Tian, Rebecca Schaffer, Zhigang He, Joshua R. Sanes
SUMMARYInjured neurons in the adult mammalian central nervous system often die and seldom regenerate axons. To uncover transcriptional pathways that could ameliorate these disappointing responses we analyzed three interventions that increase survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfc04229db3c373e551ca5e62f317935
https://doi.org/10.1101/2022.01.19.476970
https://doi.org/10.1101/2022.01.19.476970
Publikováno v:
PLoS Genetics, Vol 10, Iss 2, p e1004111 (2014)
Cone-rod homeobox (CRX) protein is a "paired-like" homeodomain transcription factor that is essential for regulating rod and cone photoreceptor transcription. Mutations in human CRX are associated with the dominant retinopathies Retinitis Pigmentosa
Externí odkaz:
https://doaj.org/article/70ee4e7ca77543bb9f07edb01c3141ad
Publikováno v:
Video Journal of Sports Medicine, Vol 4 (2024)
Background: Ulnar neuropathy at the elbow (UNE) is common, and treatment ranges from bracing and nonsteroidal anti-inflammatory drugs (NSAIDs) to surgical decompression. Prior to surgical intervention, some patients may opt to receive perineural inje
Externí odkaz:
https://doaj.org/article/3912de87df794a3fa6341090321b10fd
Autor:
Xingxing Wang, Marius Wollan, In-Jung Kim, Devon M. Chenette, Yuichi Sekine, Joshua R. Sanes, Yram Foli, Nicholas M. Tran, Stephen M. Strittmatter, Jane A. Lindborg, Kristin DeLuca, Ramakrishnan Kannan
Publikováno v:
Cell reports
SUMMARY Adult mammalian central nervous system (CNS) trauma interrupts neural networks and, because axonal regeneration is minimal, neurological deficits persist. Repair via axonal growth is limited by extracellular inhibitors and cell-autonomous fac
Autor:
Anne Jacobi, McKinzie E. Arnold, Wenjun Yan, Zhigang He, Dingchang Lin, Aviv Regev, Charles M. Lieber, Guosong Hong, Chen Wang, Inbal Benhar, Karthik Shekhar, Joshua Z. Levin, Joshua R. Sanes, Nicholas M. Tran, Irene E. Whitney, Jung Min Lee, Xian Adiconis
Publikováno v:
Neuron
PMC
PMC
© 2019 Elsevier Inc. Neuronal types in the central nervous system differ dramatically in their resilience to injury or other insults. Here we studied the selective resilience of mouse retinal ganglion cells (RGCs) following optic nerve crush (ONC),